Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis by Tiantian Wang (1688881)

“…In dextran sodium sulfate-induced mouse colitis, FHND5032 markedly reduced the disease activity index, restored colon length, preserved mucosal architecture, and repaired intestinal barrier integrity. …”

Development of a User-Friendly Dynamic Culture System for Decellularized Scaffold-Based Tissue Engineering by Shujuan Fan (8380047)

“…Compared to static controls, constructs cultured in our platform exhibited a > 5-fold increase in proliferating (Ki67+) cells and a 32-fold decrease in apoptotic (TUNEL+) cells. Hepatic functions were also significantly enhanced, with increased urea production and markedly higher expression of albumin (∼1.5-fold) and the key metabolic enzymes UGT1 (∼1.4-fold) and CYP2D6 (∼2.7-fold). …”

This figure illustrates the impact of <i>Lactobacillus reuteri</i> supplementation on cytokine concentrations in a mouse model of colitis induced by dextran sulfate sodium (DSS). by Mohsen Nazari (6299819)

Image 5_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Image 2_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Table 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.docx by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Image 3_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Image 4_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Image 1_Profiling of fecal analytes as a potential biomarker in rheumatoid arthritis.tif by Zhiyi Wang (328693)

“…This study is designed to identify a novel biomarker panel combining fecal cytokine profiles with gut barrier biomarkers to discriminate RA patients with varying disease progression.…”

Table 1_Enrichment of short-chain fatty acid-producing bacteria by pH-responsive sodium alginate and chitosan-encapsulated quercetin.docx by Qianyu Bai (21992984)

“…Compared to the DSS group, the SA-Q-CS MPs treatment group showed significant improvements, with the Disease Activity Index (DAI) and histopathological scores reduced by more than 66.9%, pro-inflammatory factor levels decreased by 65%, antioxidant levels increased over sevenfold, and tight junction protein expression elevated by more than threefold. …”

Stepped-Wedge Trial Diagram. by Sugy Choi (800862)

SPIRIT diagram for the QM2 Study. by Sugy Choi (800862)

USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology. by Amy N. Nelson (21763146)

Supplementary file 1_Benzophenone-3 remodels gut microbiota diet-dependently to exacerbate non-alcoholic fatty liver disease in zebrafish.docx by Junyan Tao (131992)

“…Co-exposure to BP3 and HFD significantly worsened hepatic steatosis, as evidenced by increased triglyceride levels, lipid droplets accumulation, and oxidative damage (elevated hepatic MDA levels and decreased hepatic CAT activity). …”

Table 2_Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling.xlsx by Lulu Tang (2664904)

“…Introduction<p>Individuals with Wilson's disease (WD) exhibit liver fibrosis, a basic pathological change that was recently demonstrated to be dynamic and reversible. …”

Table 1_Gandouling ameliorates Wilson’s disease-associated liver fibrosis in mice with associated faecal microbiome and metabolome remodeling.xlsx by Lulu Tang (2664904)

“…Introduction<p>Individuals with Wilson's disease (WD) exhibit liver fibrosis, a basic pathological change that was recently demonstrated to be dynamic and reversible. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

Stepped wedge cluster randomized trial design. by Antonio Marty Quispe (12574259)

Study group background characteristics. by Zicheng Hu (3825313)

“…This relationship changed markedly with the development of <b><i>HAD</i></b> and the underlying direct neuropathic parenchymal CNS infection, i.e., <b><i>HIVE</i></b>, in which the CSF HIV-1 RNA concentrations reached high levels, and the differences between it and the blood viral load decreased. …”