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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
marked decrease » marked increase (Expand Search)
dalys increased » also increased (Expand Search), cases increased (Expand Search)
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1
Projected global leukemia burden, 1990-2050.
Published 2025“…Conclusion: Although there has been a marked decrease in global leukemia incidence, mortality, and DALYs over the past 31 years, the rise in new cases due to population growth suggests an increasing overall disease burden by 2050. …”
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2
Correlation between HDI and EAPC.
Published 2025“…Conclusion: Although there has been a marked decrease in global leukemia incidence, mortality, and DALYs over the past 31 years, the rise in new cases due to population growth suggests an increasing overall disease burden by 2050. …”
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3
Global leukemia incidence and EAPC, 1990-2021.
Published 2025“…Conclusion: Although there has been a marked decrease in global leukemia incidence, mortality, and DALYs over the past 31 years, the rise in new cases due to population growth suggests an increasing overall disease burden by 2050. …”
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4
Table 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.docx
Published 2025“…The analysis identified marked sex-specific disparities, characterized by a 41.6% (risk ratio: 1.416, 95% CI not provided) higher mortality risk in males relative to females and a male-to-female DALYs ratio of 1.667. …”
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Data Sheet 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.csv
Published 2025“…The analysis identified marked sex-specific disparities, characterized by a 41.6% (risk ratio: 1.416, 95% CI not provided) higher mortality risk in males relative to females and a male-to-female DALYs ratio of 1.667. …”
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6
Table 2_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”
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Table 1_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”
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Table 3_The global burden of pediatric infective endocarditis (5–14 years): epidemiological patterns from 1990 to 2021 and projected trajectories.pdf
Published 2025“…Marked disparities persisted, with high-SDI regions, notably China, achieving the greatest reductions in burden, while sub-Saharan Africa and Eastern Europe exhibited stagnant or increasing rates. …”
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9
Image 1_Global burden trends and future predictions of ischemic heart disease attributable to air pollution in people aged 60 years and older, 1990–2021.jpeg
Published 2025“…Studies have shown that air pollution (AP) exacerbates the risk of cardiovascular diseases, particularly IHD, posing significant health threats to older adults and increasing disease burden. …”
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10
Supplementary Material for: Global, regional, and national epidemiology of Idiopathic Childhood Epilepsy from 1990 to 2021
Published 2025“…Regionally, Southern Latin America saw the largest increase in incidence (EAPC, 0.49), and Eastern Europe observed the most significant mortality decrease (EAPC, -4.65). …”
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11
Table 1_Epidemiological study of thyroid cancer at global, regional, and national levels from 1990 to 2021: an analysis derived from the Global Burden of Disease Study 2021.docx
Published 2025“…</p>Conclusion<p>Over the past three decades, the age-standardized prevalence rate of thyroid cancer has increased, while the age-standardized mortality rate and DALY rate have decreased. …”
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Data Sheet 1_Global, regional, and national epidemiology of otitis media in children from 1990 to 2021.docx
Published 2025“…Key risk factors identified include secondhand smoke, particulate matter pollution, low birth weight, and short gestation. Additionally, a significant inverse association was found between the SDI and the burden of OM, with age-standardized DALY rates decreasing markedly as SDI increased.…”
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Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of...
Published 2025“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”
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14
Supplementary file 1_Global trends in childhood urinary tract infections, 1990–2021: results from the GBD study.docx
Published 2025“…However, this trend reversed over the past decade, with a marked increase in incidence rates. Significant disparities in incidence rates were observed across population groups globally, stratified by sex, age, geographical location, and socioeconomic status. …”
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Data Sheet 1_Global, regional, and national burden of sudden infant death syndrome, 1990–2021: a comprehensive analysis of GBD 2021 data with insights into the impact during the CO...
Published 2025“…Mortality and DALYs rates decreased by 59% from 1990 to 2021, with marked regional differences. …”
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Data Sheet 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
Published 2025“…</p>Results<p>Globally, the incidence of IBD among children and adolescents remained stable (EAPC = −0.03%, 95% CI: −0.44–0.38), although marked regional disparities were observed. The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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Data Sheet 3_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
Published 2025“…</p>Results<p>Globally, the incidence of IBD among children and adolescents remained stable (EAPC = −0.03%, 95% CI: −0.44–0.38), although marked regional disparities were observed. The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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Supplementary file 1_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.docx
Published 2025“…</p>Results<p>Globally, the incidence of IBD among children and adolescents remained stable (EAPC = −0.03%, 95% CI: −0.44–0.38), although marked regional disparities were observed. The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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Data Sheet 4_Global burden of inflammatory bowel disease in children and adolescents, 1990–2021: trends, age-specific patterns and future projections.zip
Published 2025“…</p>Results<p>Globally, the incidence of IBD among children and adolescents remained stable (EAPC = −0.03%, 95% CI: −0.44–0.38), although marked regional disparities were observed. The incidence rates were stable or declined in high-income countries (e.g., high-income North America: EAPC = −1.07, 95% CI: −1.82–−0.32), whereas industrializing regions showed significant increases (e.g., East Asia: EAPC = 2.01, 95% CI: 1.02–3.19). …”
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20
Data Sheet 1_Global, regional, and national burden of hyperglycemia-associated colorectal cancer, 1990-2021: a systemic analysis for the Global Burden of Disease study.zip
Published 2025“…Projections suggest stable death rates but increasing YLDs, DALYs, and YLLs through 2040.</p>Conclusion<p>Hyperglycemia-associated CRC imposes an escalating global burden, marked by persistent health inequalities and rising long-term disabilities. …”