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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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13221
Video 2_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi
Published 2025“…Background<p>Guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) has been demonstrated to significantly reduce morbidity and mortality. However, many patients, especially those with advanced HFrEF, are unable to tolerate optimal GDMT due to hypotension. …”
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13222
Video 1_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi
Published 2025“…Background<p>Guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) has been demonstrated to significantly reduce morbidity and mortality. However, many patients, especially those with advanced HFrEF, are unable to tolerate optimal GDMT due to hypotension. …”
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13223
Table 1_Blood urea nitrogen-to-albumin ratio as a new prognostic indicator of 1-year all-cause mortality in patients with IPF.docx
Published 2025“…The Kaplan–Meier survival curve showed that the 1-year cumulative survival rate of IPF patients with a BAR ≥0.12 was significantly decreased compared with the patients with a BAR <0.12. …”
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13224
Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx
Published 2025“…Introduction<p>Ovarian Cancer remains a significant global health concern, with high mortality rates, largely due to late-stage diagnosis and limited treatment options. …”
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13225
Data Sheet 1_A novel bivariate nomogram for predicting sequela vaginal lesions after surgery in patients with HPV-associated cervical cancer.docx
Published 2025“…Ovarian preservation (OP) during hysterectomy and adenocarcinoma histology were found to be protective from further vaginal lesions, while elder age, FIGO stage II, and positive vaginal incision margin were significant risk factors. As for persistent HPV infection, both single and multiple genotype remarkably increased the risk of vaginal lesions, and a α-9 HPV infection (OR = 18.20) brought higher risk than non-α-9 HPV (OR = 11.76). …”
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13226
Video 3_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi
Published 2025“…Background<p>Guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) has been demonstrated to significantly reduce morbidity and mortality. However, many patients, especially those with advanced HFrEF, are unable to tolerate optimal GDMT due to hypotension. …”
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13227
Experimental protocol and behavioral evidence of perceptual learning.
Published 2025“…The shaded area represents the standard error of the mean. Significant clusters for the main effect of PRE/post training, as determined by cluster mass permutation two-tailed tests, are indicated with rectangles (p < 0.05 and p < 0.1). …”
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13228
DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi...
Published 2024“…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …”
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13229
Data Sheet 3_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.docx
Published 2025“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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13230
Table 1_Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study.docx
Published 2025“…Involvement of human serum albumin (HSA) could be a possible reason behind the inconsistency. We prospectively examined the associations between urinary enterolignans and the risk of overall and cause-specific mortality among US adults and evaluated the impact of adjusting for HSA by comparing the results before and after its inclusion as a covariate.…”
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13231
Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf
Published 2025“…After one month, the longest diameter of the left upper lung nodule decreased from 19 mm to 12 mm, and there was a notable reduction in the right hilar and mediastinal lymph nodes. …”
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13232
Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx
Published 2025“…The prevalence of depressive symptoms decreased with the adoption of more favorable lifestyle categories, with the lowest likelihood observed among individuals with a favorable lifestyle (0.35 [0.30–0.41]). …”
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13233
Data Sheet 2_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip
Published 2025“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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13234
Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx
Published 2025“…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …”
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13235
Data Sheet 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip
Published 2025“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”
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13236
Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova...
Published 2025“…Case Presentations Case 1: 89-year-old male with a retinal detachment post cataract surgery. He had subsequent surgical repair but continued to have poor and worsening vision and developed constitutional symptoms including weight loss and decreased appetite. …”
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13237
Table 1_Efficacy and safety of cadonilimab combined with AG chemotherapy in patients with unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma: a retrospect...
Published 2025“…</p>Results<p>The disease control rate (DCR) reached 85.7%, and the objective response rate (ORR) was 14.3%; the median progression-free survival (mPFS) was 7.87 months, and the median overall survival (mOS) was 11.45 months. Among patients with a decrease in CA19-9, the median overall survival was significantly prolonged (12.92 vs 8.89 months, P = 0.027); patients with a platelet-lymphocyte ratio (PLR) ≤ 165.62 had a significantly better mOS (12.37 vs 8.74 months, P = 0.025). …”
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13238
Knockouts of <i>gpr-3</i> lack cAMP signaling response to melatonin.
Published 2025“…One-way ANOVA revealed statistically significant decrease of cAMP in response to melatonin treatment in N380-1 when compared to N380-2 (p = 0.036). …”
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13239
Table 2_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”
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13240
Table 5_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx
Published 2025“…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …”