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18961
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi...
Published 2025“…</p> <p>Type 2 diabetes (T2D) is a chronic metabolic disease that affects 1 in 10 people worldwide, and cancer is now recognized as a common and severe complication of T2D. …”
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18962
DataSheet_1_Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile.docx
Published 2025“…Our results show that SARS-CoV-2 infection during the third trimester of pregnancy induces a robust antibody and cytokine response at delivery and causes a significant reduction of the SARS-CoV-2-specific IgGs transplacental transfer, with a stronger negative effect when the infection is closer to delivery.…”
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18963
Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls
Published 2025“…Background<p>Diabetic nephropathy (DN) is a major complication of diabetes, contributing significantly to end - stage renal disease. …”
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18964
Table1_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p...
Published 2024“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
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18965
Table2_Clinical efficacy of Fufang Yinhua Jiedu (FFYH) granules in mild COVID-19 and its anti-SARS-CoV-2 mechanism by blocking autophagy through inhibiting the AKT/mTOR signaling p...
Published 2024“…</p>Conclusion<p>Our results indicate that FFYH not only has good anti-viral activity against SARS-CoV-2 but also has significant efficacy against COVID-19, indicating that FFYH may be a novel complementary option for treating COVID-19.…”
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18966
Table 1_TCF3 downregulation alleviates renal fibrosis via PI3K/Akt/mTOR pathway inhibition and autophagy restoration in diabetic nephropathy.docx
Published 2025“…Both the DN rat model and HG-stimulated HK-2 cells exhibited enhanced EMT markers, with significantly increased α-SMA and vimentin expression (p < 0.001), and decreased E-cadherin levels (p < 0.001). …”
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18967
Changes in functional connectivity between NREM and REM – comparison of in vivo experimental and in silico modeling data.
Published 2025“…However, animals that underwent CFC exhibited a significant increase in the number of cell pairs that strengthen functional connectivity (during REM), as compared to baseline (K-S test comparing baseline and CFC <i>p</i> = 6.0102e-126). …”
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18968
Table 1_An empirical study on the evolution and driving factors of energy-related carbon emissions in the Yangtze River Economic Belt.xlsx
Published 2025“…The energy mix has improved, with coal’s share decreasing from 77% to 69%, while natural gas and electricity’s combined share grew from 1% to 4%. …”
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18969
Figure 2 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma
Published 2025“…<p>PD-1 blockade is minimally effective in AB12 and AE17O mouse mesothelioma tumors before or after TI. <b>A,</b> In subcutaneous AB12 mouse mesothelioma tumors, TI significantly decreased the median tumor growth time to 400 mm<sup>3</sup> from 7 days compared with 9 days in untreated TC (<i>P</i> = 0.025). …”
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18970
Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Published 2025“…<b>F,</b> Distribution of regression coefficients for linear mixed-effects models fit for each of 14,120 genes and each of the variables included in the model, with a total number of genes significantly (FDR < 0.05) associated with a variable highlighted at the top. …”
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18971
Data collected from pregnant women for the analysis of placental anemia, placental malaria, Cytokines and birth anthropometric indices
Published 2025“…Pathologies associated with PM seems to be the effect of a change in immune status from antibody-mediated immune response to cell-mediated immune response resulting into excess inflammation, oxidative stress, apoptosis, and decreased heat shock protein expression [4]. …”
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18972
USUV replicates in STAT1-sufficient peripheral tissues leading to spleen and liver pathology.
Published 2025“…<b>(G)</b> H&E staining of spleen tissue collected from mock or USUV-infected mice with a 200 µm scale bar. Decreased red pulp due to massive immune cell infiltration was observed in Vav-Cre/<i>Stat1</i><sup>fl/fl</sup> and <i>Stat1</i><sup>-/-</sup> mice. …”
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18973
Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer”
Published 2025“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”
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18974
Digitized maps of vascular plant species distributions in Denmark in the early 20th century
Published 2025“…<p dir="ltr"><b>Historic data are essential for quantifying changes in biodiversity and drivers thereof. A large part of such legacy data are stored undigitized in archives at e.g., natural history museums, and make up significant untapped resources for insights into past biodiversity patterns. …”
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18975
Table1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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18976
Improved estimation of soil organic carbon stock in subtropical cropland of Southern China based on digital soil mapping and multi-sources data
Published 2025“…Soil properties, soil management practices, and lithological factors affect SOCD mainly through direct way while terrain, climate, and biota mainly via indirect way. Additionally, the mean value of SOCD significantly decreased from 3.23 in the 1980s to 2.95 kg m<sup>−2</sup> in the 2010s. …”
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18977
DataSheet1_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.docx
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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18978
Table2_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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18979
Table4_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”
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18980
Table3_The long-term prognostic implications of free triiodothyronine to free thyroxine ratio in patients with obstructive sleep apnea and acute coronary syndrome.jpg
Published 2024“…The FT3/FT4 ratio between OSA and non-OSA patients was not significantly different. During 2.8 (1.4, 3.5) years follow up, the risk of MACCE increased with the decreasing FT3/FT4 tertiles in patients with OSA (tertile3 as reference, tertile2: hazard ratio (HR) 1.26, 95% CI: 0.85-1.86, P = 0.255; tertile1: 1.60, 95% CI 1.11-2.32; P = 0.013). …”