بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
point increase » unit increase (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
point increase » unit increase (توسيع البحث)
-
18961
Table 5_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx
منشور في 2025"…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …"
-
18962
Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of...
منشور في 2025"…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …"
-
18963
Table 1_Spatio-temporal patterns and determinants of persistent catastrophic health expenditure in China: evidence from the China Family Panel Studies.docx
منشور في 2025"…Background<p>The escalating out-of-pocket medical expenses pose a significant threat to the financial stability of households worldwide. …"
-
18964
Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx
منشور في 2025"…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I<sup>2</sup> = 99%, p < 0.001) was observed across studies.…"
-
18965
Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx
منشور في 2025"…The overall TB resistance rates were significantly higher in the main urban areas. During the study period, the proportion of mono-resistance tuberculosis (MR-TB), multidrug-resistant tuberculosis (MDR-TB) and polydrug-resistant tuberculosis (PDR-TB) decreased by 59.2% (12.9–5.3%), 40.3% (12.4–7.4%), and 68.3% (6.9–2.2%), respectively. …"
-
18966
Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls
منشور في 2025"…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …"
-
18967
Image 1_Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial.j...
منشور في 2025"…However, the increases in these inflammatory markers were significantly greater in Group C than in Group T (p < 0.05). …"
-
18968
Table 2_Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.xlsx
منشور في 2025"…Disproportionality analysis revealed that Abemaciclib was significantly increased signal of venous thromboembolism (ROR = 2.57 [2.24-2.96]), whereas cardiac arrhythmia (ROR = 2.51 [2.13-2.96]) and torsade de pointes/QT prolongation (ROR = 5.7 [5-6.5]) were showed significantly disproportionate for ribociclib. …"
-
18969
Supplementary Material for: Association of umbilical cord blood serotonin levels with neurodevelopmental outcomes
منشور في 2025"…Cord blood 5-HT was significantly associated with the Mullen Composite Score, and follow-up analyses revealed a significant association between cord blood 5-HT and fine motor skills. …"
-
18970
Table 5_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"
-
18971
Table 1_Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.xlsx
منشور في 2025"…Disproportionality analysis revealed that Abemaciclib was significantly increased signal of venous thromboembolism (ROR = 2.57 [2.24-2.96]), whereas cardiac arrhythmia (ROR = 2.51 [2.13-2.96]) and torsade de pointes/QT prolongation (ROR = 5.7 [5-6.5]) were showed significantly disproportionate for ribociclib. …"
-
18972
Table 4_Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.xlsx
منشور في 2025"…Disproportionality analysis revealed that Abemaciclib was significantly increased signal of venous thromboembolism (ROR = 2.57 [2.24-2.96]), whereas cardiac arrhythmia (ROR = 2.51 [2.13-2.96]) and torsade de pointes/QT prolongation (ROR = 5.7 [5-6.5]) were showed significantly disproportionate for ribociclib. …"
-
18973
Table 3_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"
-
18974
Table 1_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"
-
18975
Table 3_Emerging cardiovascular toxicity associated with CDK4/6 inhibitors: real-world insights from the FDA adverse event reporting system.xlsx
منشور في 2025"…Disproportionality analysis revealed that Abemaciclib was significantly increased signal of venous thromboembolism (ROR = 2.57 [2.24-2.96]), whereas cardiac arrhythmia (ROR = 2.51 [2.13-2.96]) and torsade de pointes/QT prolongation (ROR = 5.7 [5-6.5]) were showed significantly disproportionate for ribociclib. …"
-
18976
Table 2_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"
-
18977
Table 1_Impact of individualized tidal volume strategies on intraoperative lung protection and inflammatory markers in laparoscopic cholecystectomy: a randomized controlled trial.d...
منشور في 2025"…However, the increases in these inflammatory markers were significantly greater in Group C than in Group T (p < 0.05). …"
-
18978
Data Sheet 1_Level of discharge readiness and influencing factors in ischaemic stroke patients: a descriptive, cross-sectional study.doc
منشور في 2025"…Statistical analyses were performed using SPSS 26.0, with significant results visualised in GraphPad Prism 9.0. …"
-
18979
Table 6_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"
-
18980
Table 4_Microbiota–sphingolipid pathway in generalized epilepsy: evidence from Mendelian randomization and clinical metabolomics.xlsx
منشور في 2025"…In contrast, Gamma-proteobacteria and Oxalobacter demonstrated bidirectional mediation: via glutamine conjugate of C<sub>6</sub>H<sub>10</sub>O<sub>2</sub>(2) and cerotoylcarnitine (C<sub>26</sub>) (P = 0.026 and P = 0.033, respectively); while these pathways were protective in mediation, higher abundances were associated with increased risk of generalized epilepsy. Notably, no significant mediators were identified for epilepsy or focal epilepsy. …"