Supplementary Material for: Preliminary efficacy, tolerability, and safety analysis of Darolutamide for metastatic castration‑resistant prostate cancer: a single-center, open-label... by Yu J. (3610580)

“…The median time to PSA50 in the Darolutamide group was 1.5 months (95%CI 0.2619- 0.9545), significantly lower than that in the placebo group (3.0 months [95%CI 1.048- 3.818], p= 0.0259); The median time to PSA90 in the experimental group was 4 months (95%CI 0.3094- 1.437), 2 months shorter than that in the placebo group (6.0 months [95%CI 0.6961- 3.232]).With the median follow-up of 6 months, , the median decrease in serum PSA was -81.8% (range -60.4 to -99.9%) in the Darolutamide group and -69.4% (range -50.3 to -89.6%) in the placebo group. …”

Data Sheet 1_Impact of meteorological factors on influenza incidence in Wuxi from 2014 to 2019: a time series and comprehensive analysis.docx by Menglan He (3768739)

“…For a unit increase in weekly average pressure, temperature, wind speed, relative humidity, precipitation, and sunshine duration, the risk of influenza increased by 7.37%, decreased by 8.39%, decreased by 33.83%, increased by 6.44% when relative humidity was >68.86%, increased by 19.91% when precipitation was ≤ 6.13 mm, and decreased by 11.41% when sunshine duration was ≤ 6.30 h, respectively. …”

Data Sheet 1_Association between life’s crucial 9 and severe abdominal aortic calcification in U.S. Adults: the mediating role of the systemic inflammatory response index.docx by Kaifeng Tang (5993231)

“…Mediation analysis revealed that the SIRI significantly influenced the linkage between LC9 and SAAC, accounting for 5.8% of the mediation effect, with a statistically significant p-value (P < 0.001).…”

Supplementary Material for: Association of MTHFR gene with type 2 diabetes mellitus: A case-control study and meta-analysis by figshare admin karger (2628495)

“…Results: In case-control study at the C677T(rs1801133), we found that compared with the AA genotype, GG + GA genotype was associated with an increased risk of T2DM (OR=1.605; 95% CI: 1.229–2.095; P=0.001); compared with the GG/GA genotype, AA genotype was associated with a decreased risk of T2DM (OR=0.620; 95% CI: 0.450–0.855; P=0.004; OR=0.625; 95% CI: 0.470–0.830; P=0.001). …”

Table 1_Immune checkpoint proteins are associated with persistently high liver stiffness after successful HCV treatment in people with HIV: a retrospective study.docx by Rubén Martín-Escolano (17411991)

“…Although LSM values showed a decreasing trend over the years following successful HCV treatment, this trend was not statistically significant due to substantial variability among PWH. …”

Supplementary file 1_Effectiveness and impact of intravenous magnesium sulfate in spinal surgery systematic review and meta-analysis.docx by Zhaoguo Jin (21563024)

“…Magnesium sulfate administration significantly reduced pain scores at 24 h (MD −0.18, 95% CI: −0.34 to −0.02) and decreased opioid consumption (SMD −0.34, 95% CI: −1.07 to −0.35). …”

Causal associations between kidney function and aortic valve stenosis: a bidirectional Mendelian randomization analysis by Wanqian Pan (18147420)

“…In addition, the evidence did not support a significant causal association of AVS on kidney function.…”

Data from: Population structure varies among four western North American bumble bee species by Elizabeth Sakulich (22077908)

“…Although we expected range-wide genetic differentiation for species with more narrow niche requirements, we found evidence of this differentiation for all four study species, with western populations experiencing significant genetic structure relative to inland populations. …”

Automated matching and visualisation of magnetic flux leakage data in shale gas pipeline based on ICP and DBSCAN algorithm by Leyao Gu (17897654)

“…The results indicate that the average distance error of matched defects between two datasets decreased by 72.5%, and the overlap rate increased by 20%. …”

Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx by Ahmed Alsafar (21716735)

“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”

Data Sheet 4_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Ma... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

Data Sheet 3_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Ma... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

Table 1_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

Table 2_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

Data Sheet 2_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Ma... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

<p></p><p></p><p dir="ltr"><b>Trends in GP dispensing of thickeners in the NHS England, 2019-24</b></p> by ARLENE MCCURTIN (22819052)

“…Thickened liquids is primarily an intervention for older people although there was a significant decreasing trend in dispensed thickener items in adult populations. …”

Data Sheet 1_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Ma... by Cameron R. S. Thompson (20622296)

“…The connectivity exhibited strong seasonal patterns, with peak connectivity occurring during spring and early summer, aligning with the sand lance feeding period on C. finmarchicus. We found significant interannual variability, influenced by changes in the strength of the MCC and circulation patterns in the western Gulf of Maine. …”

Table 4_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential... by Daniel Leduc (9191783)

“…These spatially consistent patterns reflect the influence of methane seepage, which appears limited to the inner 150-200 m radius of each area, on nematode abundance via input of chemosynthetic food sources. We found significant differences in nematode community structure among all three areas, with most of the heterogeneity in community structure between the shallow Urutī South area and deeper Maungaroa and Glendhu areas, and differences among nematode communities of high, medium and low abundance associated with site-specific gradients in methane seepage. …”

Table 1_Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential... by Daniel Leduc (9191783)

“…These spatially consistent patterns reflect the influence of methane seepage, which appears limited to the inner 150-200 m radius of each area, on nematode abundance via input of chemosynthetic food sources. We found significant differences in nematode community structure among all three areas, with most of the heterogeneity in community structure between the shallow Urutī South area and deeper Maungaroa and Glendhu areas, and differences among nematode communities of high, medium and low abundance associated with site-specific gradients in methane seepage. …”

Table 1_The role of eosinophils and their activation state in hypereosinophilia-associated heart disease.pdf by Usman Sunusi (22274329)

“…The proportion of cells expressing surface CD274 increased on both neutrophils and eosinophils, particularly in mice that showed inflammation by histology. There was no significant increase in expression of CD101. Finally, we assessed whether activation markers can be induced on eosinophils in vitro. …”