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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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14561
Antioxidants gene expressions in two tissues suspected to be involved in Decompression Sickness (DCS) triggering, in DCS resistant rats_Data
Published 2025“…At the opposite, in the liver, we observed a decreased expression in both group of genes (except for <i>Pgc1α</i>), related to a selection effect.…”
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14562
Table 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx
Published 2025“…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…”
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14563
Data Sheet 1_Global, regional, and national burden of fracture of vertebral column, 1990–2021: analysis of data from the global burden of disease study 2021.docx
Published 2025“…Background<p>Fractures of the vertebral column, encompassing various spinal injuries, represent a significant public health burden worldwide. These injuries can lead to long-term disability, reduced quality of life, and substantial healthcare costs.…”
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14564
Data Sheet 1_Investigation of the physiological and molecular regulatory mechanism of soluble sugar metabolism in Lavandula angustifolia Mill. under cold stress.docx
Published 2025“…<p>Lavender (Lavandula angustifolia Mill.) is a valuable aromatic plant with significant commercial importance. However, cold stress–one of the primary abiotic factors impacting sugar metabolism–adversely affects its agricultural productivity in Northeast China. …”
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14565
Data Sheet 1_Enhancing chronic low back pain management: an initial neuroimaging study of a mobile interoceptive attention training.pdf
Published 2024“…</p>Results<p>MyP led to significant decreases in PEG scores overall. Furthermore, MyP responders exhibited increased pain-related activation in key brain regions, including the contralateral posterior insula, bilateral ventral anterior insula, ventral anterior cingulate, dorsolateral prefrontal cortex, and nucleus accumbens. …”
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14566
<i>Neisseria</i> species on the tonsillar surface predicts favorable clinical outcomes in patients with Immunoglobulin A nephropathy who underwent tonsillectomy
Published 2025“…However, there were no significant differences in the clinical course, except for renal survival rates, between patients with and without <i>Neisseria</i> sp. at the tonsillar center. …”
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14567
<b>Canagliflozin-induced adaptive metabolism in bone</b>
Published 2025“…Significant metabolic adaptations to CANA were evident as early as 1.5 months post-treatment, specifically in male mice. …”
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14568
Table 1_Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome.docx
Published 2025“…The impact of age was significant, with OBS benefits only observed in those aged 40 and older.…”
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14569
Climate is more influential to vegetation green-up than factors that contribute to erosion following high-severity wildfire
Published 2025“…In <a>highly erodible</a> scenarios, when accounting for growing season climate, coefficient of variation for year-of-fire precipitation, total precipitation, and soil erodibility decreased greenness in the fifth year. While the effects of year-of-fire factors related to erosion were significant, they were small, and the variability explained by growing season vapor pressure deficit and growing season precipitation were significantly greater.…”
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14570
Glial 5-HT<sub>2a</sub> receptors are necessary and rate limiting for experience-dependent synaptic glomeruli pruning.
Published 2024“…All the individual data points are shown with mean ± SEM. Significance is indicated as <i>p</i> < 0.0001 (****) and <i>p</i> > 0.05 (not significant, ns). …”
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14571
Cell surface sialic acid is not required for SARS-CoV-2 spike glycoprotein binding.
Published 2024“…Statistical significance was assessed by two-way ANOVA (****p<0.0001; ns, not significant).…”
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14572
Data Sheet 1_Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics.docx
Published 2025“…</p>Results<p>ATM treatment (160 mg/kg) observably ameliorated insulin resistance (IR), hyperglycemia, hyperlipemia and pathological injury in the liver and pancreas. In addition, ATM significantly decreased the expression of TNF-α, IL-1β, IL-6, NF-κB and IL-17A, and significantly increased the level of IL-10 in diabetic mice. 16S rRNA sequencing and targeted GC-MS metabolomics result indicated that ATM restored gut microbiota dysbiosis based on increasing beneficial bacteria Lactobacillus and reducing pathogenic bacteria Helicobacter and Prevotella leading to the accumulation of propionic and valeric acids and the reduction of lipopolysaccharides (LPS) release, intestinal inflammation and intestinal barrier damage. …”
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14573
Table 1_Effect of Ebenatide on glycemic metabolism and body fat in patients with type 2 diabetes mellitus.docx
Published 2025“…</p>Results<p>The Ebenatide group showed significantly lower in hemoglobin A1c (HbA1c), mean blood glucose (MBG), time above range (TAR) and standard deviation (SD), along with improvement of time in range (TIR) at Week 24 and Week 52 compared to baseline (P<0.05). …”
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14574
Soil carbon, nitrogen, and phosphorus stoichiometry in subtropical forests of Zhejiang, China
Published 2025“…<p dir="ltr"><a href="" target="_blank">Soil carbon (C), nitrogen (N), and phosphorus (P) stoichiometry in regional forests has garnered significant attention, yet reported distribution patterns and variation often show discrepancies and even contradictions. …”
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14575
Inc exhibits key properties of a Cul3 adaptor in neurons in vivo.
Published 2025“…Neuronal <i>Cul3</i> RNAi decreases <i>Cul3</i> transcript levels but does not significantly alter those of <i>inc</i>. …”
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14576
Interactive effects of temperature and food ration on growth and mercury concentration in eastern brook trout
Published 2025“…Across a range of temperatures (16 – 24°C), Brook Trout growth rate decreased, and Hg concentration increased with temperature. …”
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14577
Table 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.xlsx
Published 2025“…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …”
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14578
Data Sheet 1_Lipopolysaccharide affects metabolic processes and energy homeostasis in the corpus luteum.xlsx
Published 2025“…The analysis showed that these proteins are involved in processes such as glucose metabolism, the tricarboxylic acid cycle (TCA), detoxification processes as well as steroid biosynthesis in the CL. Moreover, we demonstrated that LPS decreases glucose levels and increases progesterone levels in the CL.…”
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14579
Efficient Optimization of Plasma Radiation Detector Configurations using Imperfect Inference Models
Published 2025“…Among other diagnostics, several detectors are placed with significant standoff from the fusion target to capture the x-rays emitted by the fusion plasma, which can be used to infer some of its properties. …”
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14580
Image 1_Foxr1 deletion causes microcephaly and leads to cortical and hippocampal hypoplasia.tif
Published 2025“…Cortical thinning is primarily driven by a significant reduction in layer 2/3 neurons, linked to impaired generation of later-born neurons. …”