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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
year increase » linear increase (Expand Search), may increase (Expand Search)
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19001
Table 1_Inflammatory parameters mediates the relationship between dietary index for gut microbiota and frailty in middle-aged and older adults in the United States: findings from a...
Published 2025“…RCS showed that the risk of frailty decreased linearly with increasing DI-GM levels. Mediation analysis indicated significant effects for leukocyte count, neutrophil count, NLR, and SIRI, with mediation proportions of 5.7, 7.9, 4.4, and 5.5%, respectively (all p < 0.001).…”
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19002
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19003
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19004
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19005
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19006
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19007
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19008
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19009
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19010
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19011
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19012
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19013
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19014
First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity
Published 2024“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D<sub>3</sub>, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”
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19015
Data Sheet 1_Global burden of inflammatory bowel disease in the elderly: trends from 1990 to 2021 and projections to 2051.docx
Published 2024“…Death number increased from 14,400 to 33,490, but the age-standardized mortality rate decreased from 3.21 to 2.84 per 100,000. …”
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19016
Supplementary file 1_Mechanism of soil microbial community degradation under long-term tomato monoculture in greenhouse.docx
Published 2025“…Results demonstrated a significant increase in fungal abundance and diversity in >10 years samples, alongside reduced bacterial richness. …”
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19017
Presentation 1_Global, regional, and national burden of cardiovascular disease attributable to high body mass index from 1990 to 2021 and projection to 2045.pptx
Published 2025“…Over the study period, the overall CVD burden attributable to HBMI decreased significantly, while the burden of atrial fibrillation and flutter increased. …”
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19018
Table 2_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…</p>Results<p>The global ASMR of PAH decreased from 0.35 (per 100,000 population) in 1990 to 0.27 (per 100,000 population) in 2021, with an annual percentage change of −0.82, while number of deaths increased from 14,842 in 1990 to 22,021 in 2021, an increase of 48.37%. …”
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19019
Table 1_Mortality and trends of pulmonary arterial hypertension, 1990–2021: a population-based study.docx
Published 2025“…</p>Results<p>The global ASMR of PAH decreased from 0.35 (per 100,000 population) in 1990 to 0.27 (per 100,000 population) in 2021, with an annual percentage change of −0.82, while number of deaths increased from 14,842 in 1990 to 22,021 in 2021, an increase of 48.37%. …”
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19020
Table 1_Global, regional, and national burden of four major neurological diseases in women from 1990 to 2021.xlsx
Published 2025“…</p>Results<p>In 2021, an estimated 6191564.2, 572999.9, 1536118.7, and 39191.7 new cases of female AD and other dementias, Parkinson’s disease, multiple sclerosis, and idiopathic epilepsy were reported globally, with a significant increase in age-standardized incidence rate (ASIR) from 1990 to 2021. …”