OMT by Jingmin Ou (19669426)

“…OMT was found to significantly increase the apoptosis rate of endothelial cells (ECs) treated with oxidised low-density lipoprotein (ox-LDL), as measured by caspase-3 activity assay and flow cytometry. qRT-PCR results showed that OMT treatment decreased the expression of miR-199a-5p in ECs.Transfection of miR-199a-5p mimics enhanced the apoptotic effect, whereas miR-199a-5p inhibitors attenuated apoptosis, suggesting that miR-199a-5p has a key regulatory role in EC apoptosis. …”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

DataSheet1_Physiological characteristics during the formation of aromatic components in xylem of Aquilaria sinensis induced by exogenous substances.docx by Shengjiang Pang (19455217)

“…The defense hormone contents of jasmonic acid, salicylic acid, aminocyclopropane-1-carboxylic acid, and abscisic acid obtained from the four induction treatments increased significantly. However, the concentrations of gibberellin and indoleacetic acid were decreased compared to the control group. …”

DataSheet2_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

DataSheet1_FOXO1-mediated autophagy regulation by miR-223 in sepsis-induced immunosuppression.ZIP by Guoan Xiang (383282)

“…</p>Results<p>We found that when the expression of miR-223 increased, FOXO1 expression decreased and autophagy decreased; whereas, when FOXO1 expression was inhibited, autophagy decreased significantly in different cell models after LPS induction.…”

Data Sheet 1_Metabolomics analysis of aqueous humor from patients with high-myopia complicated nuclear cataract.pdf by Qiuyi Huo (21398225)

“…</p>Conclusion<p>This work identified valuable metabolic biomarkers and pathways that may improve understanding HMnC pathogenesis. Here, we found that a decrease in glutathione might promote the occurrence of HMnC. …”

Data Sheet 2_Metabolomics analysis of aqueous humor from patients with high-myopia complicated nuclear cataract.pdf by Qiuyi Huo (21398225)

“…</p>Conclusion<p>This work identified valuable metabolic biomarkers and pathways that may improve understanding HMnC pathogenesis. Here, we found that a decrease in glutathione might promote the occurrence of HMnC. …”

DataSheet1_Clerodendranthus spicatus [Orthosiphon aristatus (Blume) Miq.] maintains uric acid homeostasis via regulating gut microbiota and restrains renal inflammation in hyperuri... by Yang Wang (5921)

“…Also known as C. spicatus, which has a significant therapeutic effect on hyperuricemia nephropathy (HN), however, the specific mechanism of its action is still unknown.…”

Data Sheet 1_Determining the influence of tree age on tea quality-related metabolites in Camellia tachangensis var. remotiserrata by integrating metabolomic and transcriptomic anal... by Zhuorong Shi (22589729)

“…Levels of relatively abundant phenolic acids (e.g., ferulic acid-4-O-glucoside, p-coumaric acid-4-O-glucoside) and flavonoids (e.g., luteolin-3’-O-glucoside, apigenin-4’-O-glucoside) decrease, while catechin content increases significantly, particularly epigallocatechin gallate derivatives. …”

Supplementary Material for: First European Experience of Shape-Sensing Robotic-assisted bronchoscopy: Learning Curve Analysis by figshare admin karger (2628495)

“…There is limited data on how quickly this new technology can be learned. Methods: This study presents a post-hoc analysis of learning curves from a single-centre prospective study in which PPN were diagnosed by ssRAB combined with standalone (non-integrated) mobile cone-beam computed tomography (mCBCT) by two experienced proceduralists both nascent to ssRAB and mCBCT. …”

Data Sheet 4_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Introduction<p>Diabetic nephropathy (DN) is a major complication of diabetes, with renal fibrosis leading to progressive renal function decline. …”

Data Sheet 2_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Introduction<p>Diabetic nephropathy (DN) is a major complication of diabetes, with renal fibrosis leading to progressive renal function decline. …”

Data Sheet 1_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Introduction<p>Diabetic nephropathy (DN) is a major complication of diabetes, with renal fibrosis leading to progressive renal function decline. …”

Data Sheet 3_Balanophora polysaccharide improves renal injury and fibrosis in db/db diabetic nephropathy mice via NLRP3 inflammasome mediated inflammation.pdf by Chaoxi Tian (22702289)

“…Introduction<p>Diabetic nephropathy (DN) is a major complication of diabetes, with renal fibrosis leading to progressive renal function decline. …”

Detection of Tn-antigen in breast and prostate cancer models by VVL-labeled red dye-doped nanoparticles by Alejandra Verhassel (19823895)

“…</p> <p><b>Conclusion:</b> VVL-labeled nanoparticles could provide a new tool for the detection of Tn-antigen-expressing breast and prostate cancer cells.…”

Clinical and biochemical determinants of length of stay, readmission and recurrence in patients admitted with diabetic ketoacidosis by Fateen Ata (12217764)

“…<p>The increasing prevalence of diabetic ketoacidosis (DKA) related admissions poses a significant burden on the healthcare systems globally. …”

Data Sheet 1_Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra.docx by Siyuan Liu (696701)

“…<p>In order to explore the molecular mechanisms of Populus simonii × P. nigra response to stress and screen for genes conferring resistance to Alternaria alternata, we carried out measurements of physiological and biochemical indices and transcriptomic sequence analysis of leaves of Populus simonii × P. nigra inoculated with A. alternata. The results showed that the variation trends of multiple hormone contents and enzyme activities were broadly similar at different time points, with H₂O₂, SA, JA, PPO, SOD, PAL and POD showing a trend of increasing and then decrease after inoculation with the pathogen. …”

Table 1_Integrative transcriptome and WGCNA analysis reveal key genes mainly in response to Alternaria alternata in Populus simonii × P. nigra.xlsx by Siyuan Liu (696701)

“…<p>In order to explore the molecular mechanisms of Populus simonii × P. nigra response to stress and screen for genes conferring resistance to Alternaria alternata, we carried out measurements of physiological and biochemical indices and transcriptomic sequence analysis of leaves of Populus simonii × P. nigra inoculated with A. alternata. The results showed that the variation trends of multiple hormone contents and enzyme activities were broadly similar at different time points, with H₂O₂, SA, JA, PPO, SOD, PAL and POD showing a trend of increasing and then decrease after inoculation with the pathogen. …”

Image 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…Conversely, this upregulation led to a significant increase in alternative splicing events of genes implicated in DKD, such as hnRNPA2B1, OSML, UGT2B7, TRIP6, and IRF3. …”