Data Sheet 1_Breaking the cancer code: a novel DNA minicircle to disable STAT3 in ovarian cancer cells SKOV3.docx by Adina-Gabriela Vasilescu (22236073)

“…Introduction<p>Ovarian Cancer remains a significant global health concern, with high mortality rates, largely due to late-stage diagnosis and limited treatment options. …”

Data Sheet 1_A novel bivariate nomogram for predicting sequela vaginal lesions after surgery in patients with HPV-associated cervical cancer.docx by Yueheng Liu (9228588)

“…Ovarian preservation (OP) during hysterectomy and adenocarcinoma histology were found to be protective from further vaginal lesions, while elder age, FIGO stage II, and positive vaginal incision margin were significant risk factors. As for persistent HPV infection, both single and multiple genotype remarkably increased the risk of vaginal lesions, and a α-9 HPV infection (OR = 18.20) brought higher risk than non-α-9 HPV (OR = 11.76). …”

Video 3_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi by Lina Feng (509270)

“…Background<p>Guideline-directed medical therapy (GDMT) for heart failure (HF) with reduced ejection fraction (HFrEF) has been demonstrated to significantly reduce morbidity and mortality. However, many patients, especially those with advanced HFrEF, are unable to tolerate optimal GDMT due to hypotension. …”

DataSheet1_Causal effects of serum calcium, phosphate, and 25-hydroxyvitamin D on kidney function: a genetic correlation, pleiotropic analysis, and Mendelian randomization study.zi... by Yanjun Liang (4394089)

“…Similarly, serum P was associated with a decrease in eGFRcrea (beta −0.01, P-value 2.0E−04; beta −0.005, P-value 2.0E−03) and an increase in BUN (beta 0.02, P-value 3.0E−03; beta 0.02, P-value 7.5E−07). …”

Data Sheet 3_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.docx by Li Cui (37567)

“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Table 1_Associations of urinary enterolignans and risk of overall and cause-specific mortality with or without serum albumin adjustment: a prospective cohort study.docx by Zisuo Sun (22310437)

“…Involvement of human serum albumin (HSA) could be a possible reason behind the inconsistency. We prospectively examined the associations between urinary enterolignans and the risk of overall and cause-specific mortality among US adults and evaluated the impact of adjusting for HSA by comparing the results before and after its inclusion as a covariate.…”

Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf by Yifan Yang (170387)

“…After one month, the longest diameter of the left upper lung nodule decreased from 19 mm to 12 mm, and there was a notable reduction in the right hilar and mediastinal lymph nodes. …”

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…The prevalence of depressive symptoms decreased with the adoption of more favorable lifestyle categories, with the lowest likelihood observed among individuals with a favorable lifestyle (0.35 [0.30–0.41]). …”

Data Sheet 2_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip by Li Cui (37567)

“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Table 1_Global, regional, and national disease burden and economic costs of cervical cancer (1991–2021): a multidimensional data synthesis analysis.docx by Yidi Ma (9507153)

“…Objectives<p>Cervical cancer remains a significant global health concern, particularly in less developed regions. …”

Data Sheet 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.zip by Li Cui (37567)

“…Data extraction and quality assessment were independently conducted by two researchers, and Bayesian network meta-analysis was performed using R software.</p>Results<p>A total of 128 RCTs were included. ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova... by figshare admin karger (2628495)

“…Case Presentations Case 1: 89-year-old male with a retinal detachment post cataract surgery. He had subsequent surgical repair but continued to have poor and worsening vision and developed constitutional symptoms including weight loss and decreased appetite. …”

Table 1_Efficacy and safety of cadonilimab combined with AG chemotherapy in patients with unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma: a retrospect... by Wenke Qin (20390989)

“…</p>Results<p>The disease control rate (DCR) reached 85.7%, and the objective response rate (ORR) was 14.3%; the median progression-free survival (mPFS) was 7.87 months, and the median overall survival (mOS) was 11.45 months. Among patients with a decrease in CA19-9, the median overall survival was significantly prolonged (12.92 vs 8.89 months, P = 0.027); patients with a platelet-lymphocyte ratio (PLR) ≤ 165.62 had a significantly better mOS (12.37 vs 8.74 months, P = 0.025). …”

Knockouts of <i>gpr-3</i> lack cAMP signaling response to melatonin. by Cathryn S. D. Maienza (20629929)

“…One-way ANOVA revealed statistically significant decrease of cAMP in response to melatonin treatment in N380-1 when compared to N380-2 (p = 0.036). …”

PDS and CEP inhibited DDX60-mediated promotion of CCHFV replication. by Yutong Sui (11151669)

Table 1_Association between excessive screen time and falls, with additional risk from insufficient sleep duration in children and adolescents, a large cross-sectional study in Chi... by Runquan Zhang (20393850)

“…After adjusting for relevant covariates, the associations remained significant (aOR: 1.30, 95% CI: 1.08–1.56, p = 0.006; aOR: 1.43, 95% CI: 1.10–1.87, p = 0.008).…”

Table 1_Association between eating behavior patterns and the therapeutic efficacy of GLP-1 receptor agonists in individuals with type 2 diabetes: a multicenter prospective observat... by Yuya Koide (22261300)

“…</p>Results<p>GLP-1RA therapy significantly reduced HbA1c, body weight, and body fat percentage at 12 months. …”

Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx by Elia Asanterabi Swai (15337336)

“…Introduction<p>Caring for physically disabled children, particularly in contexts where resources are often insufficient or absent, exposes primary carers to significant psychological strain. The lack of structured mechanisms to address this psychological burden poses a considerable threat to the wellbeing of both carers and the children with disabilities under their care. …”

Data Sheet 1_Disease spectrum of patients with hospital-acquired multidrug-resistant organism infections in the intensive care unit: a retrospective study.doc by Xiaowu Wang (167537)

“…</p>Conclusion<p>Our data show the mortality rate of hospital-acquired MDRO infections decreased during COVID-19 and increased after restrictions eased. …”

Table1_Radiotherapy plus lenvatinib versus radiotherapy plus sorafenib for hepatocellular carcinoma with portal vein tumor thrombus: a retrospective study.docx by Min Zhang (111999)

“…The most common adverse events were myelosuppression, decreased liver function, fatigue, diarrhea, nausea, and vomiting. …”