Multicomponent physical exercise program among community-dwelling older adults who are users of home care services: a quasi-experimental pilot study by Aida Ruiz-Fernández (22822586)

“…Group-by-time analyses suggested improvements in the MPEP group for the Short Physical Performance Battery (η²ₚ=0.154) and Fried Frailty Scale (η²ₚ=0.164). Frailty decreased on both scales (OR = 0.142 and 0.125). No further significant effects were observed.…”

Table 1_Effectiveness and safety of hydrogen inhalation therapy as an additional treatment for hypertension in real-world practice: a retrospective, observational study in China.do... by Hongxiang Ji (11235519)

“…</p>Conclusion<p>The HI therapy is related to significant amelioration in BP levels with acceptable safety profile in Chinese hypertensive adults after 24 weeks of treatment, building a clinical ground for further research to evaluate the antihypertensive effect of HI therapy.…”

Data Sheet 1_Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-anal... by Yong Tian (1461202)

“…There was no statistically significant decrease in CD8⁺ cells. For inflammation, lower-dose Tα1 could significantly reduce C-reactive protein (CRP) levels (mg/L) (MD=-30.12, 95%CI [-35.75, -24.49], P<0.00001), while higher-dose Tα1 showed no statistically significant difference (MD=-3.83, 95%CI [-12.14, 4.49], P=0.37). …”

Data Sheet 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.csv by Zehao Jin (11408687)

“…Significant socioeconomic disparities were observed, with low-to-middle SDI regions bearing a disproportionate share (75.0%) of the global high non-optimal temperature-related mortality burden. …”

Table 1_Abnormal subthalamic nucleus functional connectivity and machine learning classification in Parkinson’s disease: a multisite functional magnetic resonance imaging study.doc... by Bin Qin (544949)

“…Introduction<p>Parkinson’s disease (PD) is a progressive neurodegenerative disorder imposing a significant global burden, characterized by motor dysfunction linked to aberrant basal ganglia activity. …”

The acutely infected population at an endemic equilibrium, for different <i>α</i> values. by Meriem Boukaabar (19704258)

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

Data_Sheet_1_Joint association of serum sodium and frailty with mild cognitive impairment among hospitalized older adults with chronic diseases: a cross-sectional study.docx by Zhaozhao Hui (10221125)

“…</p>Conclusion<p>Both lower and higher serum sodium impose a significantly higher risk for MCI in older adults with frailty. …”

Presentation1_Systematic review of Buzhong Yiqi method in alleviating cancer-related fatigue: a meta-analysis and exploratory network pharmacology approach.PPTX by Ji Zeng (4336561)

“…Conversely, PFS, TCM syndrome score, and adverse reaction assessments significantly decreased. The primary active ingredients in its core drugs may exert a positive therapeutic effect on CRF by targeting molecules such as AKT1, IL6, IL1B, PTGS2, CASP3, ESR1, and BCL2, as well as through signaling pathways including TNF, IL17, TLR, NF-κB, and C-type lectin receptor.…”

Table 1_Immune checkpoint proteins are associated with persistently high liver stiffness after successful HCV treatment in people with HIV: a retrospective study.docx by Rubén Martín-Escolano (17411991)

“…Although LSM values showed a decreasing trend over the years following successful HCV treatment, this trend was not statistically significant due to substantial variability among PWH. …”

Data Sheet 1_Variations in mood states among Brazilian air force pilots: a crossover analysis between operational and aerobatic flight missions.xlsx by Wilian de Jesus Santana (22673252)

“…</p>Results<p>OM flights were associated with a statistically significant increase in depression scores post-flight (p = 0.031), alongside a non-significant trend toward decreased tension (p = 0.098). …”

<i>MMP-1</i> OE restores <i>5HT</i>_<i>2A</i><i>R</i>-deficient experience-dependent pruning. by Vanessa Kay Miller (19775496)

“…<i>MMP-1</i> OE restores synaptic pruning with a significant decrease of innervation volume in response to the EB odorant experience (blue, <i>n</i> = 10/condition, <i>p</i>-value = 4.43 × 10⁻¹³), which is nearly identical to the control. …”

Table 1_Impact of comorbid burden on global left cardiac function and prediction models for myocardial function damage: a cardiac magnetic resonance feature-tracking study.docx by XiaoFeng Qu (20718092)

“…</p>Results<p>After adjustment, the left atrial (LA) reservoir strain (p = 0.011) and conduit strain (p < 0.001) were significantly lower in patients with a comorbid burden ≥2. …”

Data Sheet 1_From demyelination to neurodegeneration in multiple sclerosis: reassessing the role of visual evoked potential P100-N145 amplitudes: a missing piece of the puzzle?.zip by Nurhan Kaya Tutar (22327474)

“…</p>Results<p>EDSS progression was observed in 17.8% of patients. A longitudinal decrease in P100–N145 amplitude from baseline to follow-up was significantly associated with EDSS progression (OR: 1.511, 95% CI, p < 0.001). …”

Supplementary file 1_The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018.docx by Ying Wang (11406)

“…</p>Conclusion<p>There is a significant negative correlation between LC9 and infertility, with BRI playing a partial mediating role. …”

Data Sheet 1_The association of diabetic retinopathy and diabetic kidney disease in patients with type 2 diabetes mellitus: a prospective observational research study.pdf by Yutong Wu (3130584)

“…As DR severity increased, the levels of three DKD indicators presented a significant upward trend compared to those in the control group, except for Hcy in the PDR subgroup. …”

Table 1_A species of Coprococcus is related to BMI in patients who underwent malabsorptive bariatric surgery and its abundance is modified by magnesium and thiamin intake.docx by Fernando Suárez-Sánchez (7552866)

“…The Shannon and Simpson diversity indices decreased significantly after surgery (p < 0.001). …”

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf by Zhen Wang (72451)

“…The prevalence of abnormal blood glucose markers—FBG, 2h OGTT, and HbA1C—significantly decreased within each intervention group after short-term intervention and 6 months of follow-up. …”

Data Sheet 1_Enhancing tofacitinib’s therapeutic efficacy in murine arthritis with a synbiotic formulation comprising Bacillus megaterium DSM 32963 and an Omega-3 fatty acid lysine... by Annette Zehrer (21422849)

“…The ldTofa+Syn combination also led to a notable reduction in C-reactive protein (CRP) and markers of NETosis in joint tissue, with a significant decrease in neutrophil chemokine CXCL1 observed only in synbiotic-containing groups. …”