Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf by Fisal Tantoush (20936264)

“…<p>Chronic lymphocytic leukaemia (CLL) is an uncurable haematological malignancy and is associated with significant infection morbidity. Bruton’s tyrosine-kinase inhibitors (e.g., ibrutinib) have improved disease outcomes, but severe infections and poor immunization responses afflict patients. …”

Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx by Lin Zhang (8926)

“…Notably, we observed significant changes in immune cell populations, including reductions in macrophages (510 to 58 cells), NK cells (445 to 91 cells), and granulocytes (1597 to 1 cells). …”

Table 1_Altered Th17/Treg balance and therapeutic targeting of RORγ in primary focal hyperhidrosis.docx by Min Lin (17652)

“…</p>Results<p>PFH patients exhibited a disrupted Th17/Treg balance, with increased Th17 and decreased Treg cells across all subtypes compared to controls. …”

Raw data by Jiaxin Wang (21706805)

“…The results of this study indicate that compared to the model group, the content of regulatory enzymes and main products (mainly GCK) of the glycolytic pathway significantly decreased after administration of Rb1, and the key enzyme ACC for fatty acid synthesis also significantly decreased.…”

DataSheet2_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.xlsx by Yuqing Lu (1282527)

“…D-mannose treatment significantly reduced inflammation by decreasing the expression of proinflammatory cytokines and inflammation mediators. …”

DataSheet1_D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis.pdf by Yuqing Lu (1282527)

“…D-mannose treatment significantly reduced inflammation by decreasing the expression of proinflammatory cytokines and inflammation mediators. …”

PMS repressed ferroptosis in T2DM mice. by Hongmin Zhao (20710544)

“…<p>(a,b) TUNEL staining results demonstrated that the number of cell death in the pancreas of T2DM mice was significantly decreased following PMS intervention. …”

N6-methyladenosine modification of THBS1 induced by affluent WTAP promotes Graves’ ophthalmopathy progression through glycolysis to affect Th17/Treg balance by Lin-na Li (20442989)

“…WTAP was significantly upregulated in CD4⁺ T cells of GO, and WTAP silencing significantly reduced m6A abundance and expression of THBS1. …”

Susceptibility of RUNX1 promoter rs2071029 polymorphism to adjuvant chemotherapy-induced neutropenia in CRC by Xikai Luo (21520875)

“…RUNX1 promoter SNP rs2071029T had a decreased risk of severe CIN compared with rs2071029C. …”

Effects of DERL3 overexpression or knockdown on proliferation of ccRCC cells. by Chengtao Niu (21212827)

“…<p>(A, B, C): Plate cloning experiments confirmed that overexpression of DERL3 significantly increased the number of ccRCC colonies, while knocking down DERL3 expression reduced the number of ccRCC colonies; (D, E): MTT experiments showed that the Optical Density in the DERL3 overexpression group was significantly increased, while that in the DERL3 knockdown group was significantly decreased; (***p<0.001).…”

Table 1_Changes in the energy metabolism of the gills of Litopenaeus vannamei under carbonate alkalinity stress and recovery conditions.doc by Meng Xiao (591353)

“…In detail, after CA stress, carbohydrate metabolism related indexes, the pyruvate (PYR) content showed increases, as did the relative expression of the hk, pk, and pdh genes, while the glucose (GLU) and lactate (LAC) content and the expression of the idh gene were slightly decreased; lipid metabolism related indexes, such as the triglycerides (TG) content and the expression of the ampk gene were slightly increased, and the expressions of the srebp, acc, and fas genes were increased significantly; tricarboxylic acid (TCA) cycle related indexes, such as the expressions of the cs, odh, and sdh genes were up-regulated, whereas the expressions of the mdh and idh genes were significantly down-regulated, the expression of the fh gene was slightly decreased in regulation; electron transfer chain related indexes, such as the expressions of the ndh, cytc, coi, cco, and atph genes were significantly increased. …”

Baseline characteristics of the four groups. by Chao Yang (174810)

“…When the HAR was at a low level, mortality within 28 days after ICU admission decreased significantly as the HAR increased. …”

Flow of included patients through the trial. by Chao Yang (174810)

“…When the HAR was at a low level, mortality within 28 days after ICU admission decreased significantly as the HAR increased. …”

Cox proportional hazards modeling. by Chao Yang (174810)

“…When the HAR was at a low level, mortality within 28 days after ICU admission decreased significantly as the HAR increased. …”

Lesioning silent neurons reveals functional role. by Thomas S. Wierda (22404198)

“…Mixed-selective neurons, however, lead to a decreased accuracy when lesioned.</p> <p>(TIFF)</p>…”

Supplementary file 1_First exposure to second-generation antipsychotics alters gut microbiota and metabolic profiles in patients with glucose-lipid metabolism disorders.docx by Yuexia Wu (10755903)

“…</p>Results<p>Firstly, Gut microbial diversity differed significantly between groups. At genus level, the abundances of Escherichia and Bifidobacterium were increased significantly in the post-medication patients, while the abundances of Faecalibacterium and Blautia were decreased. …”

Supplementary Material for: Exploring the ability of novel choroidal biomarkers in predicting treatment outcomes of polypoidal choroidal vasculopathy by Zhang Y. (2828780)

“…The greater change of central macular thickness (CMT) was significantly correlated with increased CMT (P=0.030), decreased CT (P=0.042) and decreased CVI (p=0.038) at baseline. …”

Figure 2 from Mathematical Modeling Unveils Optimization Strategies for Targeted Radionuclide Therapy of Blood Cancers by Maxim Kuznetsov (20201548)

“…<b>C,</b> Dependence of minimal single curative dose, <i>A</i>_<i>cur</i>, on relative significance of self-damage, <i>k</i>_<i>s</i>. …”

Data Sheet 1_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.zip by Quan Lin (5958)

“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”

Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…SQOR knockdown resulted in decreased cell viability, decreased migration ability and increased MDA level under hypoxic Ersatin induced conditions. …”