<b>Metabolic Perturbations and Ectopic Fat Deposition in Low Birthweight Subjects</b><b>– Effects of a 4 Week Carbohydrate Overfeeding Challenge</b> by Charlotte Brøns (261017)

“…<p dir="ltr">Low birthweight (LBW) is a risk factor for type-2 diabetes (T2D). We hypothesized that 4-weeks carbohydrate overfeeding (COF) with +25% energy would unmask key T2D perturbations among 22 non-obese LBW men, including 5 with screen-detected metabolic dysfunction–associated steatotic liver disease (MASLD), compared with 21 healthy normal birthweight (NBW) controls. …”

Refractive Profiles in Children Receiving School-Based Eye Exams Following Vision Screening from a Large School-Based Vision Program in 2016 to 2022 by Andrew M. Nguyen (20176426)

“…The odds of hyperopia, astigmatism, and anisometropia decreased with higher grade level.</p> <p>Over 80% of students who failed vision screening at a large school-based vision program had CSRE, and over 60% had RAR. …”

Data Sheet 1_Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease.pdf by Yan Wu (70890)

“…The results showed that at 12 months of age, the hemizygous Tg-SwDI mice spent significantly more time in non-rapid eye movement (NREM) sleep (44.6 ± 2.4% in Tg-SwDI versus 35.9 ± 2.5% in WT) and had a much shorter average length of wake bout during the dark (active) phase (148.5 ± 8.7 s in the Tg-SwDI versus 203.6 ± 13.0 s in WT). …”

Table 1_Characteristics and trends of unintentional injuries among children and adolescents in Kunshan, China: a hospital-based retrospective study, 2018–2023.docx by Li Shen (110858)

“…Unintentional injury cases decreased significantly during COVID-19 (2020–2022). …”

Table 1_Impact of dual residual risk of cholesterol and inflammation on adult male sex hormones: a cross-sectional study from NHANES.docx by Yang Zhou (65942)

“…Notably, hs-CRP exhibited a non-linear correlation with TT, SHBG, and FT, with distinct inflection points. …”

Table 1_Sex-specific association between triglyceride-glucose index and all-cause mortality in patients with osteoporotic fractures: a retrospective cohort study.docx by Shao-han Guo (19690687)

“…However, in males, there was a non-linear correlation, where patients in the uppermost TyG-I tertile showed a substantially decreased mortality risk relative to those in the lowest tertile (HR: 0.53, 95% CI: 0.30–0.92, p = 0.02). …”

Data Sheet 1_Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence.docx by Omkar B. Ijare (22274167)

“…Importantly, alanine detection via magnetic resonance spectroscopy offers promising potential for non-invasive glioma diagnostics. Furthermore, targeting cholesterol esterification pathways using Acyl-CoA:cholesterol acyltransferase inhibitors could provide a novel therapeutic approach, especially for low-grade astrocytomas with high risk of malignant progression and recurrence.…”

Table 1_Differential brain activity in patients with disorders of consciousness: a 3-month rs-fMRI study using amplitude of low-frequency fluctuation.docx by Xuewei Qin (20426600)

“…</p>Results<p>Patients with TBI showed increased ALFF in the thalamus and anterior cingulate cortex, whereas the middle occipital lobe showed decreased ALFF. In the non-TBI group, a higher ALFF was noted in the precuneus, with a reduced ALFF in the occipital and temporal lobes. …”

Data_Sheet_1_Association of systemic immune-inflammation index with malnutrition among Chinese hospitalized patients: a nationwide, multicenter, cross-sectional study.docx by Mengyuan Chen (5633153)

“…Q₁, OR = 1.83, 95%CI: 1.67–2.00). However, a significant reduction in prevalence was observed when SII was in the second quartile (Q₂ vs. …”

Table 1_Differences in the dynamic balance function of healthy elementary school students and university students observed with and without the use of a sensor-integrated gamificat... by Yasuaki Kusumoto (2634931)

“…The results of multiple comparison tests indicated different responses between groups attributable to sensor game use. No significant differences in the Y-Balance test items with or without the use of the sensor game for the dominant and non-dominant legs were observed in the university student group. …”

Image 2_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…Compared with the non-diabetic group, the diabetic group had a higher incidence of complications in acute respiratory distress syndrome (ARDS), shock, acute heart injury, acute kidney injury and more regularly used oxygen therapy, invasive ventilation, non-invasive ventilation, continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) treatment. …”

Image 3_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…Compared with the non-diabetic group, the diabetic group had a higher incidence of complications in acute respiratory distress syndrome (ARDS), shock, acute heart injury, acute kidney injury and more regularly used oxygen therapy, invasive ventilation, non-invasive ventilation, continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) treatment. …”

Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif by Kai Liu (159026)

“…Compared with the non-diabetic group, the diabetic group had a higher incidence of complications in acute respiratory distress syndrome (ARDS), shock, acute heart injury, acute kidney injury and more regularly used oxygen therapy, invasive ventilation, non-invasive ventilation, continuous renal replacement therapy (CRRT), extracorporeal membrane oxygenation (ECMO) treatment. …”

Image 1_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

Image 2_L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China.tiff by Yanqin Li (499034)

“…Below this threshold, each 10-unit increase in TyG-BMI was associated with a 6% decrease in self-rated mental health risk (adjusted hazard ratio [aHR] = 0.94, 95% confidence interval [CI]: 0.90–0.99). …”

Table 1_Ultrasonographic assessment of optic nerve sheath diameter on the affected and unaffected sides as a predictor of clinical deterioration at discharge in patients with large... by Changlan Li (704841)

“…Ultrasonographic optic nerve sheath diameter (ONSD) measurement provides a non-invasive method for estimating intracranial pressure. …”

Data Sheet 1_Biomarker-based risk assessment of dietary intervention in patients with coronary artery disease during cardiac rehabilitation—a quasi-experimental study.pdf by Mona Kotewitsch (12479136)

“…Total cholesterol, LDL, and triglyceride levels also decreased in all groups during CR without significant differences (p ≥ 0.3957). …”

Data Sheet 1_Acceptance of sexual attraction and its link to psychological distress and sexual offending among pedohebephilic clients: results from a preliminary analysis.pdf by Anna Konrad (20620994)

“…In a subsample of 197 pedohebephilic individuals (n = 197), correlations with recent sexual behavior were minimal. …”

Table 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.docx by Lauren Stewart Stafford (17937497)

“…</p>Results<p>Following SOCS1-KIR pretreatment, cell proliferation significantly decreased in control, but not ERU-derived PBMCs. …”

Supplementary Material for: Comparing malposition and complications associated with Ultrasound-guided versus Radiography-guided central catheter tip-position in neonates: A Systema... by figshare admin karger (2628495)

“…Ultrasound-guided catheter tip-position significantly reduced malposition rates (3 RCTs, N=181, RR 0.51, CI 95% 0.37 to 0.70; 4 NRSs, N=1110, RR 0.25, CI 95% 0.11 to 0.57) and decreased the need for X-rays (2 RCTs, N=112, MD -1.22, CI 95% -2.32 to -0.11; 2 NRSs, N=401, MD -0.31, CI 95% -0.47 to -0.15). …”