Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
non decrease » nn decrease (Expand Search), point decrease (Expand Search), note decreased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
non decrease » nn decrease (Expand Search), point decrease (Expand Search), note decreased (Expand Search)
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Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation.
Published 2025“…(<b>C</b>) Quantification of relative (normalized to average control in each experiment) gMFIs of TMRM (<i>n</i> = 5 per group) and MitoTracker Deep Red (<i>n</i> = 8 for control mixed BM chimera mice and 10 for <i>Foxp3</i><sup>Cre</sup><i>Atg14</i><sup>fl/fl</sup> mixed BM chimera mice) in TCRβ<sup>+</sup>CD4<sup>+ </sup>Foxp3-YFP<sup>+</sup>CD44<sup>low</sup>CD62L<sup>high</sup> cTregs and TCRβ<sup>+</sup>CD4<sup>+ </sup>Foxp3-YFP<sup>+</sup>CD44<sup>high</sup>CD62L<sup>low</sup> eTregs derived from the spleen of control or <i>Foxp3</i><sup>Cre</sup><i>Atg14</i><sup>fl/fl</sup> mixed BM chimera mice, as determined by flow cytometry analysis. gMFI, geometric mean fluorescence intensity. (<b>D</b>) Quantification of the relative frequencies (normalized to average control in each experiment) of FVD<sup> +</sup> non-viable CD44<sup>low</sup>CD62L<sup>high</sup> cTregs and CD44<sup>high</sup>CD62L<sup>low</sup> eTregs among total TCRβ<sup>+</sup>CD4<sup>+ </sup>Foxp3<sup> +</sup> Tregs (all pre-gated on CD45.2<sup> +</sup> cells) derived from the spleen of control (<i>n</i> = 10) or <i>Foxp3</i><sup>Cre</sup><i>Atg14</i><sup>fl/fl</sup> (<i>n</i> = 9) mixed BM chimera mice. …”
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CONSORT diagram.
Published 2024“…Statistically significant (<i>p</i><0.01) decreases in emotional loneliness and depressive symptoms were observed following the intervention. …”
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GWAS analysis using Cluster 3 data (shown in S1 Fig).
Published 2024“…(C) The corresponding non-synonymous (circles) amino acid changes that associate with increased or decreased viral copies. …”
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GWAS analysis using Cluster 4 data (shown in S1 Fig).
Published 2024“…(C) The corresponding synonymous (triangles) and non-synonymous (circles) amino acid changes that associate with increased or decreased viral copies. …”