eIF3d1 phosphorylation but not cap-binding is required for CySC self-renewal. حسب Ruoxu Wang (9312306)

"…(<b>B</b>) Number of Zfh1⁺ Eya⁻ CySCs in testes in which wild-type (eIF3d1^WT), phospho-mimetic (eIF3d1^DD) or phospho-dead (eIF3d1^NN) eIF3d1 was over-expressed. Phospho-dead eIF3d1 expression results in a significant decrease in CySC numbers (<i>N</i> ≥ 18 testes, * <i>P</i> < 0.05, ns <i>P</i> = 0.1150 (eIF3d1^WT) or <i>P</i> > 0.9999 (eIF3d1^DD), Kruskal-Wallis test). …"