Data Sheet 2_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.docx by Guilin Ren (18720749)

“…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …”

Table 6_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx by Guilin Ren (18720749)

“…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …”

Table 1_Elucidating the impact of organic amendments on soil bacterial communities and strawberry yield in North Carolina.xlsx by Tika B. Adhikari (9310247)

“…S. A. The main objective of the study was to examine the effects of reduced rates of dried molasses (5.60 t/ha) and mustard meal (2.24 t/ha), a half-rate combination of both, a positive control (Pic Clor 60), and a negative control (no fumigated and no amended) on soil bacterial communities and strawberry yield. …”

Supplemental file for Training alters cytokine and soluble receptor responses by Jeremy Ducharme (20174820)

“…Following 1-hour of cycling at their respiratory compensation point, untrained men (n=5) exhibited a significant increase in pro-inflammatory cytokines, including IL-6, TNF-α, IL-1β, CCL2, and VEGFA. …”

Table 5_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xls by Guilin Ren (18720749)

“…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …”

Rht1 functions in cell cycle progression and modulates fluconazole susceptibility. by Ci Fu (148006)

“…<p><b>A)</b><i><i>Candida albicans</i></i> strains were sub-cultured to an OD₆₀₀ of 0.2 in YPD and grown at 30 °C for 4 h. …”

Table 1_Vitamin D3 promotes white fat beige through IL-27/P38MAPK/PGC-1α pathway.docx by Yanqiu Zhou (2172931)

“…Meanwhile, there was a significant increase in mRNA and protein expression for VDR, IL-27R, P38MAPK, and PGC-1α. …”

Data Sheet 1_Global burden of inflammatory bowel disease in the elderly: trends from 1990 to 2021 and projections to 2051.docx by Ying Liu (18461)

“…The age-standardized incidence rate (ASIR) rose from 8.01 to 8.77 per 100,000, while the age-standardized prevalence rate (ASPR) slightly decreased from 118.14 to 117.29 per 100,000. Death number increased from 14,400 to 33,490, but the age-standardized mortality rate decreased from 3.21 to 2.84 per 100,000. …”

<b>Contrasting strategies, shared risk: 12-yr nitrogen addition compromises hydraulic safety in young and mature trees via distinct pathways</b> by Shijie Ning (17757825)

“…We found that, in young trees, N50 decreased soluble sugars in leaves, twigs, and branches, but increased in roots, suggesting a preferential belowground allocation, whereas N20 responses were limited. …”

Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Image 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.tif by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Table_1_Olfactory dysfunction as an early pathogenic indicator in C. elegans models of Alzheimer's and polyglutamine diseases.xlsx by Weikang Xue (19768329)

“…We found that the ER unfolded protein response (UPR) is significantly activated in worms expressing Aβ1-42. Activation of the AMPK pathway alleviates olfactory defects and reduces fibrillar Aβ in these worms. …”

Data Sheet 1_Long-term nitrogen fertilization alters the partitioning of amino acids between citrus leaves and fruits.docx by Yuanlai Zhao (20548445)

“…As fruits entered the swelling stage, a significant positive correlation emerged between fruiting branch leaves and fruit total N content (R²=0.68), while the R² for leaves on non-fruiting branches dropped to 0.47, indicating a shift in N supply towards leaves on fruiting branches. …”

Sustainable separation of Xe from the noble gas mixture of Ar, Kr, and Xe using cryogenic distillation and gas hydrates hybrid methods by Saeideh Babaee (16908064)

“…From all the simulated processes, a hydrate-hybrid process was found to be the best-performing configuration, achieving the desired separation of xenon with significant energy savings. …”

Table1_Intranasal dexmedetomidine sedation for EEG in children with autism spectrum disorder.xlsx by Arianna De Laurentiis (19829892)

“…No significant adverse events were reported in either period. …”

Supplementary file 1_Effect of liraglutide on the dysglycemia, inflammation, and gut microbiota in prediabetic KKay mice.xlsx by Ying Zhang (40767)

“…<p>Prediabetes is a significant risk factor for type 2 diabetes mellitus (T2DM). …”

Oral L-Arginine Treatment Attenuates<i>Cryptococcus neoformans</i>Extrapulmonary Dissemination and Disease Progression by Adithap Hansakon (21708473)

“…We found significant depletion of serum L-arginine and its downstream metabolites, accompanied by increased arginase activity in infected tissues, indicating a disrupted metabolic balance. …”

QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>A sustained zero-order drug release was obtained for both the formulations.…”

Supplementary file 1_Characterization of the gut microbiota in people with different levels of obesity.docx by Ergan Li (22142026)

“…Purpose<p>With the evolution of dietary habits, obesity has emerged as a significant global health issue. Numerous studies have demonstrated a close association between obesity and gut microbiota; however, the specific contribution of gut microbiota to varying degrees of obesity remains inadequately understood. …”

Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation. by Stefanos Giannakopoulos (15628394)

“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”