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18401
Image 1_Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization.jpeg
Published 2025“…Inflammatory markers (p < 0.05) and migration ability of LPS-activated monocytes were significantly reduced after CTSS agonist. In addition, CTSS agonist decreased the pulmonary tissue monocyte/macrophages infiltration in septic mice.…”
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18402
Data Sheet 1_α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach.docx
Published 2025“…</p>Results<p>The results of the study demonstrated that α-MT significantly reduced the urinary excretion of albumin and creatinine, improved kidney function, and decreased renal fibrosis in db/db mice. …”
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18403
Design, synthesis and biological evaluation of marine naphthoquinone-naphthol derivatives as potential anticancer agents
Published 2024“…Further mechanistic studies revealed that compound <b>13</b> significantly induced cell apoptosis by increasing the expression levels of cleaved caspase-3 and reducing Bcl-2 proteins through downregulating the EGFR/PI3K/Akt signalling pathway, leading to the inhibition of proliferation in HCT116 and PC9 cells. …”
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18404
Supplementary Material for: A common variant in NID1 gene associated with the prognosis of heart failure
Published 2025“…Western blot analysis demonstrated that the protein level of NID1 was significantly higher in the rs3738530-T allele compared to the A allele (P < 0.05). …”
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18405
Table 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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18406
Image 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18407
Image 2_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.tif
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18408
Table 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18409
Image 1_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.jpeg
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18410
Supplementary file 1_The gut commensal Faecalibacterium hominis attenuates indole—AhR signaling and restores ASD—like behaviors with BTBR mice.docx
Published 2025“…Oral administration of 4P-15 significantly reduced the intestinal levels of indole, indole-3-propionic acid (IPA), and indole-3-acetic acid (IAA), as well as the level of IPA in brain. …”
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18411
Table 5_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.docx
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18412
Image 1_Integrative multi-omics analysis and experimental validation identify molecular subtypes, prognostic signature, and CA9 as a therapeutic target in oral squamous cell carcin...
Published 2025“…In vitro experiments validated CA9 as a promising therapeutic target, with its knockdown significantly inhibiting OSCC cell proliferation and migration.…”
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18413
Table 7_Comparative genomics and metabolomics reveal phytohormone production, nutrient acquisition, and osmotic stress tolerance in Azotobacter chroococcum W5.xlsx
Published 2025“…Wheat seed inoculation significantly enhanced germination metrics, seedling vigor, and altered carbohydrate metabolism in the seed endosperm. …”
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18414
LRIG1 and CDK6 expression in the lateral ventricular wall cells
Published 2025“…Although the <i>Cdk6</i> mRNA decreases significantly in the neuroblasts, the DCX+ neuroblasts still show a lot of td-sfGFP immunoreactivity.…”
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18415
Supplementary file 2_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx
Published 2025“…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …”
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18416
Supplementary file 1_Effects of Lactiplantibacillus plantarum DSM 33464 in children with elevated blood lead levels: a randomized, double-blind, placebo-controlled study.docx
Published 2025“…Introduction<p>Approximately one-third of the world’s children have elevated blood lead levels (BLLs), which may lead to often-irreversible decreased intelligence, behavioral difficulties, and learning problems. …”
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18417
Table 1_Alterations in sulcal depth and associated functional connectivity in schizophrenia with auditory verbal hallucinations.docx
Published 2025“…</p>Results<p>Schizophrenia patients with auditory verbal hallucinations exhibited significantly increased sulcal depth in left hemispheric regions including the lingual gyrus, cingulate gyrus, pericalcarine cortex, parahippocampal gyrus, superior frontal gyrus, cuneus, and precuneus, whereas decreased sulcal depth was observed in right hemispheric regions encompassing the superior parietal gyrus, superior frontal gyrus, lingual gyrus, lateral occipital cortex, fusiform gyrus, postcentral gyrus, middle frontal gyrus, precentral gyrus, inferior temporal gyrus, precuneus, and parahippocampal gyrus compared to schizophrenia patients without auditory verbal hallucinations. …”
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18418
Table 3_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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18419
Image 3_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”
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18420
Table 2_Integrated metagenomics and metabolomics analysis reveals dynamic changes of microbiota and metabolic profile during fermentation of cigar tobacco (Nicotiana tabacum L.) le...
Published 2025“…We observed a decreasing trend in total soluble sugars, starch, total nitrogen, and nicotine levels as fermentation progressed. …”