Search alternatives:
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
larger decrease » marked decrease (Expand Search)
range increase » large increases (Expand Search), rapid increase (Expand Search), rate increased (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
larger decrease » marked decrease (Expand Search)
range increase » large increases (Expand Search), rapid increase (Expand Search), rate increased (Expand Search)
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2121
Including non-sigmoidal melting curves in peptide-level TPP-TR datasets largely increases the number of discoveries.
Published 2024“…(A) Considering non-conventional melting curves in the analysis makes it possible to include almost twice (1.78) as many phospho-peptides compared to the published melting point (<i>T</i><sub><i>m</i></sub>) analysis. (B) By increasing the phospho-peptides coverage, GPMelt captures about five times more (4.9) mono-phosphorylated peptides than the published <i>T</i><sub><i>m</i></sub> analysis, and captures phosphosites associated with significantly higher functional scores than non-captured phosphosites (one-sided Wilcoxon signed-rank test). …”
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