بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
rate decreased » rate increased (توسيع البحث)
small decrease » small increased (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
rate decreased » rate increased (توسيع البحث)
small decrease » small increased (توسيع البحث)
-
20341
Image 4_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif
منشور في 2025"…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …"
-
20342
Figure 2 from Distant Metastases of Breast Cancer Resemble Primary Tumors in Cancer Cell Composition but Differ in Immune Cell Phenotypes
منشور في 2025"…<b>D,</b> Tumor cell phenotypic cluster enrichment in each metastatic patient group compared with average metastasis composition by differential abundance testing. Circles display significantly enriched (red) or decreased (blue; FDR < 0.05; multiple testing correction with the Benjamin–Hochberg method) results, with size indicating the log-transformed fold change.…"
-
20343
Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff
منشور في 2025"…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
-
20344
Assembly process of machine recognition form.
منشور في 2025"…Following model updates with measured data, the accumulated prediction error rapidly decreases. The proposed prediction method for shape errors during pushing exhibits high accuracy and versatility in similar projects, significantly reducing time spent on manual error handling and minimizing computational inaccuracies.…"
-
20345
Data Sheet 1_Spatiotemporal dynamics and influencing factors of native and invasive saltmarshes in a rapidly silting bay during 1985–2023.docx
منشور في 2025"…Results showed that native saltmarshes significantly decreased from 632.24 ha to complete disappearance, while S. alterniflora expanded from zero to 2872.90 ha in Yueqing Bay during 1985-2023. …"
-
20346
Negative Activation Volume in Hydrated BaZr<sub>0.8</sub>Y<sub>0.2</sub>O<sub>3−δ</sub> Proton Conductor at Room Temperature (Supporting Information)
منشور في 2025"…The bulk resistance of the material decreases as the pressure increases, with a decrement ratio from −0.6 to −2.3 % per 60 MPa variation in pressure. …"
-
20347
Image 3_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif
منشور في 2025"…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
-
20348
Unpowered dust removal system field physical map.
منشور في 2025"…Results indicate that installing a return pipe significantly reduces dust overflow caused by impact airflow during blanking. …"
-
20349
Incremental investment and maintenance costs.
منشور في 2025"…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …"
-
20350
Data set_v2.
منشور في 2025"…Experiencing a career plateau can result in negative work outcomes, including decreased job satisfaction and reduced motivation. …"
-
20351
Image 1_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif
منشور في 2025"…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …"
-
20352
Table 1_Impact of feed availability on growth performance and amino acid utilization of cobia (Rachycentron canadum) at elevated temperature.docx
منشور في 2024"…</p>Discussion<p>After six weeks, a 24-hour post-prandial analysis showed selective retention of some amino acids in muscle and plasma, but significantly higher retention in the liver at the higher temperature. …"
-
20353
Supplementary file 1_Intracerebroventricular calycosin attenuates cerebral ischemia-reperfusion injury in rats via HMGB1-dependent pyroptosis inhibition.jpeg
منشور في 2025"…</p>Results and Discussion<p>Calycosin significantly reduced neurological impairments and brain infarction in a dose-dependent manner, alleviated neuronal damage and decreased the expression of pyroptosis-related markers, including NLRP3, GSDMD, HMGB1, IL-1β, IL-18, and caspase-1. …"
-
20354
Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf
منشور في 2025"…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"
-
20355
Annual system costs and benefits.
منشور في 2025"…The results show that the system can effectively recover waste heat from the DC, significantly reducing cooling electricity consumption during the heating season and decreasing original heating steam consumption by about 25%. …"
-
20356
Data Sheet 1_Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.pdf
منشور في 2025"…Both AMK and PAMK significantly reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities compared to control. …"
-
20357
Data_Sheet_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx
منشور في 2024"…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …"
-
20358
Image 4_Viral encephalitis and seizures cause rapid depletion of neuronal progenitor cells and alter neurogenesis in the adult mouse dentate gyrus.tif
منشور في 2025"…They resumed proliferation at 14 dpi, but, did not recover to CTR levels, and displayed aberrant migration patterns. (2) The number of proliferating NSCs significantly decreased within the dorsal DG of TMEV mice at 14 dpi compared to CTR, while (3) a heightened population of proliferating astrocytes was observed. …"
-
20359
<b>Glucose</b><b>-6-Phosphatase Catalytic Subunit 3 Enhances Host Resistance to Porcine Epidemic Diarrhea Virus Through Regulating </b><b>Glycolysis/Gluconeogenesis</b>
منشور في 2025"…Notably, Glucose-6-Phosphatase Catalytic Subunit 3 (<i>G6PC3</i>) expression was significantly higher in Chinese Min piglets than in Yorkshire piglets. …"
-
20360
Image 2_Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites i...
منشور في 2024"…</p>Results<p>Results indicated that dietary RES and (or) HMB supplementation significantly improved the phenotype (mucosal thickness and villus width), SCFAs concentrations, and digestive enzymes (lipase, cellulase, and α-amylase) (p < 0.05). …"