A Novel Type of PSMA-Targeting Ligands via β‑Branched Aromatic α‑Amino Acid Modification, Bearing Enhanced Tumor Targeting and Reduced Renal Toxicity by Zong-Xiao Liu (22177765)

“…<i>In vivo</i> PET/CT imaging and biodistribution analysis revealed that β-branched aromatic α-amino acids modified PSMA radioligands could maintain or even improve tumor targeting while exhibiting a more rapid renal clearance rate than [⁶⁸Ga]Ga-<b>PSMA-617</b>. With average renal uptake of less than 10%ID/g, as opposed to 25%ID/g for [⁶⁸Ga]Ga-<b>PSMA-617</b>, this substantial decrease in renal accumulation translates to a significantly improved safety profile by minimizing nephrotoxic risks. …”

The change of disease burden of CRD by sex in Fujian, 1990-2021. by Yanrong Yin (14292683)

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The change of disease burden of CRD by age groups in Fujian, 1990-2021. by Yanrong Yin (14292683)

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The change of disease burden of CRD by categories in Fujian, 1990-2021. by Yanrong Yin (14292683)

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The proportion of attributable risk factors of DALYs of CRD in Fujian, 1990-2021. by Yanrong Yin (14292683)

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The change of attribute risk factors of DALYs in CRD in Fujian, 1990-2021. by Yanrong Yin (14292683)

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The change of disease burden of CRD in different region, 1990-2021. by Yanrong Yin (14292683)

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Sex differences and percentage change trends in smoking-attributable RA burden from 1990 to 2021. by Kaibin Lin (9911049)

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Minimal dataset for the study. by Kaibin Lin (9911049)

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Burden of RA attributable to smoking in 2021 across 204 countries and territories. by Kaibin Lin (9911049)

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Sex and age differences in smoking-attributable RA burden in 2021. by Kaibin Lin (9911049)

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Smoking-Attributable RA Burden from 2000 to 2021: Global Temporal Trends and Regional Differences in Smoking Prevalence and Burden Indicators. by Kaibin Lin (9911049)

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Relationship between SDI and smoking-attributable RA burden. by Kaibin Lin (9911049)

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Average of % peptides counts for different classes of proteins at different germination time points and significant p-value indicated as compared to soaked sample (*p< 0.05, **p<0.01, ***p<0.001) for garbanzo trypsinised with shades of green showing increase and red showing decrease with respect to soaked. by Indrani Bera (804948)

“…<p>Average of % peptides counts for different classes of proteins at different germination time points and significant p-value indicated as compared to soaked sample (*p< 0.05, **p<0.01, ***p<0.001) for garbanzo trypsinised with shades of green showing increase and red showing decrease with respect to soaked.…”

CBCHCV rawdata. This file contains the raw dataset used in the analysis of decreased levels of inflammatory markers in patients with hepatitis C virus (HCV) infection. The dataset... by Lu Han (151620)

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DataSheet1_Pharmacological inhibition of receptor protein tyrosine phosphatase β/ζ decreases Aβ plaques and neuroinflammation in the hippocampus of APP/PS1 mice.docx by Teresa Fontán-Baselga (20392470)

“…In addition, we observed a significant decrease in the number and size of astrocytes in both sexes and in the number of microglial cells in a sex-dependent manner. …”

Cardiac performance and hemolymph distribution are significantly reduced upon valve malformation. by Christian Meyer (6035)

Autophagy significantly influences the apoptotic levels of RGCs in glaucomatous mouse eyes. by Hongmei Qian (538647)

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Disease burden trends of leukemia and lymphoma analyzed by joinpoint regression analysis in mainland China. by Yu Fu (16582)

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Disease burden trends of multiple myeloma and other hematological neoplasms analyzed by joinpoint regression analysis in mainland China. by Yu Fu (16582)

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