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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
reduction decrease » reduction decreased (Expand Search), reduction reuse (Expand Search), production increases (Expand Search)
reduction rate » detection rate (Expand Search)
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19441
Data Sheet 1_Association of advanced lung cancer inflammation index with all-cause and cardiovascular mortality in US patients with asthma.pdf
Published 2025“…Background<p>Asthma poses a significant global health challenge, representing a chronic respiratory disorder marked by airway inflammation. …”
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19442
Table 1_Next-generation sequencing of mitochondrial DNA reveals pathogenic variants and protective haplogroup D4 in esophageal cancer.xlsx
Published 2025“…Notably, mitochondrial haplogroup D4 was significantly associated with a decreased risk of developing EC. …”
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19443
Data Sheet 1_Multi-compartment immune cell profiling highlights the prognostic relevance of CD127+ CD8+ T cells for patients with high-grade serous ovarian cancer.docx
Published 2025“…In addition, immune cell subsets varied significantly in their differentiation and phenotypic marker expression. …”
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19444
Image 1_Metformin enhances alpelisib sensitivity in HER2+ breast cancer by suppressing cancer stemness and oncogenic signaling.tif
Published 2025“…Combination treatment induced significant G0/G1 cell-cycle arrest, reduced ALDH1⁺ populations, and decreased tumorsphere formation. …”
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19445
Table 4_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.xls
Published 2025“…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…”
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19446
Image 2_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg
Published 2024“…In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …”
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19447
Image 1_Application and validation of the machine learning-based multimodal radiomics model for preoperative prediction of lateral lymph node metastasis in papillary thyroid carcin...
Published 2025“…Current diagnostic methods show significant limitations, with occult LLNM rates of 41.0%-51.7% requiring secondary surgeries. …”
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19448
Data Sheet 1_Visual attention during non-immersive virtual reality balance training in older adults with mild to moderate cognitive impairment: an eye-tracking study.pdf
Published 2025“…Clinical tests revealed a slight increase, though results were not statistically significant in balance and walking speed (p = 0.063). …”
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19449
Table_4_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.docx
Published 2025“…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …”
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19450
Table1_Hypoxia-induced PD-L1 expression and modulation of muscle stem cell allograft rejection.pdf
Published 2024“…In vivo, these preconditioned MuSCs led to decreased infiltration of CD4<sup>+</sup> and CD8<sup>+</sup> T cells in implanted limb muscles of mouse models. …”
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19451
Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4
Published 2025“…Bet1L knockdown decreased motor neuron size in the lumbar spinal cord, which innervated the siRNA-injected hindlimb. …”
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19452
Table 2_High intake of n-6 polyunsaturated fatty acid exacerbates non-alcoholic steatohepatitis by the involvement of multiple metabolic pathways.docx
Published 2025“…Correlational analysis revealed significant associations between these pathways and inflammatory/oxidative markers. …”
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19453
Image1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.tif
Published 2025“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”
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19454
Table 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx
Published 2025“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”
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19455
Data Sheet 6_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.pdf
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
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19456
Table 4_Global, regional, and national burden of musculoskeletal disorders, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2035.doc
Published 2025“…Frontier analysis revealed significant gaps between current burdens and achievable benchmarks, particularly in high-SDI regions, while some low-SDI regions demonstrated effective management despite limited resources. …”
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19457
Soil plant available silicon from a bamboo forest on karst mountain in southwest China differs between wet and dry seasons
Published 2025“…The soil water-soluble Si and organic matter showed no significant difference between wet and dry seasons. …”
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19458
Data Sheet 1_Radiomics reveals the biological basis for non-small cell lung cancer prognostic stratification by reflecting tumor immune microenvironment heterogeneity.docx
Published 2025“…Immune microenvironment profiling showed significantly reduced immune scores and decreased proportions of naive B cells in high-risk patients, indicating impaired immune activity. …”
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19459
Analysis diagram of Ecological carrying system.
Published 2025“…Our results indicate significant changes in land types within the TGRR from 1986 to 2020, with decreases in arable land, forest land, and grassland, while water bodies, building land, and unused land increased. …”
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19460
Table 1_Altered brain functional network connectivity and topology in type 2 diabetes mellitus.doc
Published 2025“…</p>Discussion<p>This study demonstrated significant abnormalities in connectivity and topology of large-scale brain functional networks in T2DM patients. …”