بدائل البحث:
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
role decrease » rate decreased (توسيع البحث), road decreased (توسيع البحث), note decreased (توسيع البحث)
fold decrease » fold increase (توسيع البحث), fold increased (توسيع البحث), fold increases (توسيع البحث)
significant decrease » significant increase (توسيع البحث), significantly increased (توسيع البحث)
role decrease » rate decreased (توسيع البحث), road decreased (توسيع البحث), note decreased (توسيع البحث)
fold decrease » fold increase (توسيع البحث), fold increased (توسيع البحث), fold increases (توسيع البحث)
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Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isoste...
منشور في 2025"…Considering this: (1) [Fe(PPP4pSe)<sub>2</sub>]<sup>+</sup> demonstrated increased reduction relative to [Fe(PPP4pT)<sub>2</sub>]<sup>+</sup> with glutathione and l-cysteine, while l-ascorbate led to comparable reduction; (2) glutathione led to complete dissociation of [Zn(PPP4pSe)<sub>2</sub>], while incomplete dissociation of [Zn(PPP4pT)<sub>2</sub>] occurred; and (3) [Cu(PPP4pSe)Cl] demonstrated complete coordinate sphere substitution with glutathione, l-cysteine, and l-ascorbate, whereas [Cu(PPP4pT)Cl] demonstrated partial substitution. The role of glutathione in all three latter reactions is significant, given the greater reactivity of the selenosemicarbazone, and glutathione’s key role in selenosemicarbazone and thiosemicarbazone anticancer activity.…"
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Advantages of Novel Anti-cancer Selenosemicarbazones: Preferential Reactivity of Their Fe(III), Cu(II), and Zn(II) Complexes with Key Physiological Reductants/Ligands Versus Isoste...
منشور في 2025"…Considering this: (1) [Fe(PPP4pSe)<sub>2</sub>]<sup>+</sup> demonstrated increased reduction relative to [Fe(PPP4pT)<sub>2</sub>]<sup>+</sup> with glutathione and l-cysteine, while l-ascorbate led to comparable reduction; (2) glutathione led to complete dissociation of [Zn(PPP4pSe)<sub>2</sub>], while incomplete dissociation of [Zn(PPP4pT)<sub>2</sub>] occurred; and (3) [Cu(PPP4pSe)Cl] demonstrated complete coordinate sphere substitution with glutathione, l-cysteine, and l-ascorbate, whereas [Cu(PPP4pT)Cl] demonstrated partial substitution. The role of glutathione in all three latter reactions is significant, given the greater reactivity of the selenosemicarbazone, and glutathione’s key role in selenosemicarbazone and thiosemicarbazone anticancer activity.…"
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Raw data.
منشور في 2025"…Blocking CD36 function with SSO further decreased viral infectivity, demonstrating the critical role of lipid uptake in HSV-1 life cycle. …"
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