CCND1 promoted chemoresistance in CRC. by Dequan Wang (6007007)

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Correlation between the amount of physical activity recorded PLUS CYCLE^® and video-observed activity. by Akihiro Ohnishi (10989900)

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Expression and diagnostic value of the 8 hub genes in the GSE190635 validation dataset. by Wei He (131453)

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Gene set enrichment analysis (GSEA) of the DEGs. by Wei He (131453)

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ALKL1196M –ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

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Identification of DEGs and DESRGs of AD in the GSE52093 dataset. by Wei He (131453)

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ALK^wt–ABT199 interactions. by Richard Junior Zapata Dongo (17912565)

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ALK inhibitors (Positive control) and ABT199 (Proposed binding) in complex with the ALK active side. by Richard Junior Zapata Dongo (17912565)

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Visualization of immune cell infiltration between AD and control group. by Wei He (131453)

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BCL2 protein keeps their expression in different conditions treatment nevertheless each EML4-ALK cell modells exhibit variable expression. by Richard Junior Zapata Dongo (17912565)

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Combination therapy exhibited apoptosis in Ba/F3 EML4-ALKmutant cell models. by Richard Junior Zapata Dongo (17912565)

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miR-1247-3p was downregulated in CRC resistant cells. by Dequan Wang (6007007)

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The binding energy values of ATP, ALK inhibitors and ABT-199 to ALK were obtained from AlphaFold and modeled protein structures. by Richard Junior Zapata Dongo (17912565)

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Downregulation of miR-1247-3p inhibited apoptosis and reduced chemosensitivity in cells. by Dequan Wang (6007007)

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Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. by Richard Junior Zapata Dongo (17912565)

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miR-1247-3p was downregulated in tissues of patients with CRC and was associated with prognosis and drug resistance. by Dequan Wang (6007007)

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Overexpression of miR-1247-3p promoted apoptosis and inhibited resistance in drug-resistant cells. by Dequan Wang (6007007)

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Amino acids interactions and binding energy describe that ABT-199 binds to ALK^Mutant. by Richard Junior Zapata Dongo (17912565)

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BCL2 antiapoptotic protein exhibits heterogeneous expression in Ba/F3 EML4-ALK^mutants. by Richard Junior Zapata Dongo (17912565)

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Ba/F3 EML4-ALK^mutants exhibit variable dose-response to ABT-199 treatment. by Richard Junior Zapata Dongo (17912565)

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