DAS and Y27632 down-regulated the mRNA and protein expression of CK8-RhoA/ROCK1 pathway and up-regulated TJs expression in intestines of infected mice. حسب Wen Wen Zheng (17721404)

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qPCR analysis of CK8 knockdown affecting Clauding-1 mRNA expression. حسب Wen Wen Zheng (17721404)

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Molecular-docking simulation of the TsSPc–CK8 complex in Caco-2 cells. حسب Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. حسب Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. حسب Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. حسب Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. حسب Wen Wen Zheng (17721404)

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Transcription and expression levels of CK8 in Caco-2 cells after CK8 gene was knocked down. حسب Wen Wen Zheng (17721404)

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qPCR and Western blotting of activation of CK8 receptor and RhoA/ROCK1 pathway proteins in Caco-2 cells treated with rTsSPc and IIL ES antigens. حسب Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. حسب Wen Wen Zheng (17721404)

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Intraperitoneal injection protocol for inhibitors (A), inhibitors DAS and Y27632 reduced intestinal permeability (B) and intestinal adult worm burden (C) of infected mice. حسب Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. حسب Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. حسب Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. حسب Wen Wen Zheng (17721404)

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Study variables. حسب Amit Timilsina (15203538)

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Descriptive statistics. حسب Amit Timilsina (15203538)

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Robustness analysis: Increase control variables. حسب Jianqing Zhou (112889)

Summary of significant single-arm time effect. حسب Wensheng Xiao (16557866)

Autophagy significantly increases RGCs loss. حسب Hongmei Qian (538647)

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Autophagy significantly increases RGCs loss. حسب Hongmei Qian (538647)

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