Image 7_MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma.jpeg by Yan Jiang (12139)

“…Background<p>Lung adenocarcinoma (LUAD) represents the most common form of lung cancer, contributing to significant global mortality. Metabolic reprogramming in tumor cells has been increasingly recognized as a hallmark of tumorigenesis, contributing to an immunosuppressive microenvironment. …”

Table1_APP-CD74 axis mediates endothelial cell-macrophage communication to promote kidney injury and fibrosis.XLSX by Bin Liu (5899)

“…Additionally, APP and CD74 expression were significantly increased in the UUO and IRI mouse models. …”

Data Sheet 1_Association between the age-to-serum albumin ratio and all-cause mortality in patients with acute myocardial infarction: a retrospective cohort study.pdf by Xue-Cheng Song (22679321)

“…Restricted cubic splines illustrated a significant J-shaped dose-response relationship between the A2A Index and all-cause mortality risk (P-nonlinearity < 0.001). …”

Image 5_MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma.jpeg by Yan Jiang (12139)

“…Background<p>Lung adenocarcinoma (LUAD) represents the most common form of lung cancer, contributing to significant global mortality. Metabolic reprogramming in tumor cells has been increasingly recognized as a hallmark of tumorigenesis, contributing to an immunosuppressive microenvironment. …”

Video 2_Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype.avi by Dorottya Horváth (14253557)

“…</p>Results<p>NPR1 expression was significantly higher in moLCs compared to iDCs, and treatment with ANP and BNP enhanced moLC differentiation, increasing CD207, CD1a, and HLA-DQ expression, while other tested neuropeptides (calcitonin gene-related peptide [CGRP], neurotensin) had no significant effect. …”

Video 3_Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype.avi by Dorottya Horváth (14253557)

“…</p>Results<p>NPR1 expression was significantly higher in moLCs compared to iDCs, and treatment with ANP and BNP enhanced moLC differentiation, increasing CD207, CD1a, and HLA-DQ expression, while other tested neuropeptides (calcitonin gene-related peptide [CGRP], neurotensin) had no significant effect. …”

Expression of <i>SHH</i> in the FEZ after RCAS-virus infection to induce overexpression and knockdown of <i>PBX1</i> and <i>PBX3.</i> by Chan Hee Mok (11247669)

“…Statistical significance was determined at P-value < 0.05; *, P < 0.05; **, P < 0.01; ****, P < 0.0001; ns, not significant.…”

Identifying cyst initiation candidate genes through mRNA sequencing <i>Pkd2</i> mouse kidneys at pre-cystic and early cystic time points. by Abigail O. Smith (11883787)

“…Colored dots indicate FDR <0.05, red indicates increased and blue decreased in Experimental vs Control. Plot was cropped for better visualization. (*) Data point moved for better visualization: Pkd2 [Log2(FC) = -1.13, -Log10(FDR) = 93.97], Cdkl1 [Log2(FC) = 0.42, -Log10(FDR) = 26.30]. …”

Data Sheet 1_Administration of anticoagulation strategies for portal vein thrombosis in cirrhosis: network meta-analysis.docx by Hui-Jun Li (1480486)

“…Warfarin and TIPS were recommended for reducing the frequency of bleeding events, while LMWH plus warfarin and DOACs proved to be most effective in decreasing the rate of major bleeding events. Warfarin, heparin plus DOACs plus warfarin, and DOACs demonstrated the most significant reduction in mortality rates, highlighting its potential as an effective intervention. …”

Table_1_Psychological wellbeing among carers of children and adolescents with physical disabilities in North-Eastern Tanzania—a cross-sectional survey study.docx by Elia Asanterabi Swai (15337336)

“…Notably, poor psychological wellbeing was significantly associated with symptoms of anxiety and depression. …”

Table_1_Effect of progesterone concentration on hCG trigger day on clinical outcomes after high-quality single blastocyst transfer in GnRH antagonist cycles.docx by Nan Jia (118883)

“…And the pregnancy rate decreased by 25% (95% CI: 0.51, 1.09) for frozen cycles, although there was no statistically significant (p = 0.1273). …”

DataSheet1_Drought induces opposite changes in organ carbon and soil organic carbon to increase resistance on moso bamboo.pdf by Xiaogai Ge (594675)

“…In the control treatments, SC of leaves were significantly positively correlated with ROC, NSC of branches were positively correlated with ROC and MBC, NSC of roots were significantly positively correlated with SOC.…”

Data Sheet 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.pdf by Peerapon Kiatkittikul (22801874)

“…Healthy control also showed globally increased [¹⁸F]SMBT-1 uptake. There was no significant correlation between the degree of [¹⁸F]FDOPA uptake and [¹⁸F]SMBT-1 uptake in any brain region.…”

Table 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.doc by Chanchan Xiao (9522614)

“…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”

Table 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.xlsx by Lei Xiang (528500)

“…Introduction<p>Oxyresveratrol (ORes) exhibits significant anticancer activity, particularly against breast cancer. …”

Image 1_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tiff by Keyi Yu (8958845)

“…The AAPC of the ASIR, ASPR, and ASDR in China was 0.7434%, 0.8765%, and 0.8827%, respectively, significantly outpacing the global AAPC of 0.2204%, 0.2220%, and 0.2426%, respectively. …”

Data Sheet 8_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.pdf by Erman Wu (19021269)

“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”

Data_Sheet_1_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data_Sheet_2_Genetically predicted serum metabolites mediate the association between inflammatory proteins and polycystic ovary syndrome: a Mendelian randomization study.CSV by Ming-Jie Jia (18267391)

“…</p>Results<p>The IVW method revealed that the inflammatory proteins IFN-γ (p-value = 0.037, OR = 1.396, 95% CI = 1.020–1.910) and CCL7 (p-value = 0.033, OR = 1.294, 95% CI = 1.021–1.641) were associated with an increased risk of PCOS, while IL-6 (p-value = 0.015, OR = 0.678, 95% CI = 0.495–0.929) and MMP-10 (p-value = 0.025, OR = 0.753, 95% CI = 0.587–0.967) were associated with a decreased risk. No significant evidence suggested an effect of genetically predicted PCOS on inflammatory proteins. …”

Data Sheet 1_Oxyresveratrol as a novel ferroptosis inducer exhibits anticancer activity against breast cancer via the EGFR/PI3K/AKT/GPX4 signalling axis.pdf by Lei Xiang (528500)

“…Introduction<p>Oxyresveratrol (ORes) exhibits significant anticancer activity, particularly against breast cancer. …”