P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…P4HA3 and Ki-67 were decreased in the knockdown groups by siRNA compared to the NC group. …”

Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Introduction<p>Estradiol has been shown to enhance anti-viral immunity and protect against HSV-2 infection. Previously, we reported that intranasal immunization with attenuated HSV-2 (TK-) in the presence of estradiol (E2) showed enhanced Th17 responses that led to increased anti-viral Th1 immunity in HSV-2 post-challenge. …”

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. by DIMITRIOS KIMOGLOU (20499350)

“…<br>Chronic stress disrupts the apoptotic process and contributes to<br>tumorigenesis. In particular, we seek to illustrate the epigenetic influence of stress on genes that control apoptosis, as well as the significance of the HPA axis as a therapeutic target for restoring cellular equilibrium. …”

Evolutionarily conserved and functionally important amino acids in Artemis. by Ziwen Huang (17562948)

“…<i>P</i> values were analyzed with Student <i>t</i> test. ns, not significant.</p>…”

Data Sheet 1_Prevalence and predictors of parental willingness to vaccinate daughters against human papillomavirus in Sub-Saharan Africa: a systematic review and meta-analysis.docx by Daniel Asmelash (17989939)

“…These findings underscore the critical role of parental willingness in shaping policies and initiatives aimed at increasing HPV vaccination rates and reduce the incidence of cervical cancer.…”

Image 2_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.jpeg by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 6_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.tif by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 5_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.tif by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 3_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.tif by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 1_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.tif by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 1_Neural growth patterns: how random and aligned fibers guide 3D cell organization and pseudospheroid formation.tif by Jana Hlinkova (22364014)

“…Pseudospheroids formed on both substrates, that differed in perimeter (348.5 µm on random vs. 450.5 µm on aligned fibers, p < 0.05), with no significant difference in thickness (38.4 ± 7.7 µm vs. 43.2 ± 5.5 µm). mRNA expression of connexin 43 and β3-tubulin increased significantly from day 1 to day 7 on random fibers. …”

Data Sheet 1_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.docx by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Image 4_Dendritic cell-derived MYD88 potentiates as a biomarker for immune regulation in hepatocellular carcinoma and may predict a better immunological result.tif by Zheming Liu (485827)

“…</p>Results<p>Our pan-cancer data analysis further highlights the significant impact of MYD88 on clinical outcomes in HCC. …”

Data Sheet 1_Advanced lung cancer inflammation index and its predictive value for all-cause and cardiovascular mortality among osteoarthritis patients: a NHANES-based study from 20... by Guiyou Wu (9226967)

“…Background<p>Globally, the occurrence of osteoarthritis (OA) is increasing, and the intensity of the condition is frequently determined by the level of inflammation and nutritional status in a person. …”

Figure 5 from Functional Profiling of p53 and RB Cell Cycle Regulatory Proficiency Suggests Mechanism-Driven Molecular Stratification in Endometrial Carcinoma by Zelei Yang (18491142)

“…<p>Aurora kinase B inhibitor sensitive endometrial carcinoma cells show more rapidly decreasing percentages of mitotic cells than resistant models in the setting of nocodazole-induced microtubule instability. …”

SEAwise Report on the impacts of fisheries on stocks and landings under SEAwise EBFM by Dorleta Garcia (12315201)

“…The ecosystem model generally showed less optimistic outcomes under climate change, with significant decreases in biomass and catches in both the Celtic and North Seas. …”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Ybx1 regulation of its target mRNAs is m⁵C-depdendent (Related to Fig 5). by Jian Zhang (1682)

“…<p><b>(A)</b> RT-qPCR confirmed the decreased expression levels of Ybx1 target mRNAs in neural stem cells with Ybx1 knockdown using siRNA. …”

Table 1_COVID-19 pandemic increased ESKAPEEc bloodstream infections and amplified carbapenem resistance in Chinese children: a multicenter surveillance study (2016–2023).xls by Xiaoqiang Li (612879)

“…Between 2016–2019 and 2020–2023, resistance to ceftazidime and gentamicin decreased in Escherichia coli and Klebsiella pneumoniae while resistance to imipenem and meropenem increased. …”