Data Sheet 2_Qinggan Yipi capsule ameliorates hepatic fibrosis in rats by down-regulating the TGF-β1/Smad2/3 signaling pathway and improving gut microbiota imbalance.pdf حسب Wenjing Xue (2880686)

"…GO and KEGG analyses indicated that QgYp significantly affects TGF-β signaling pathway. In addition, the results of qPCR and Western blot analysis from both in vitro and in vivo experiments indicated that QgYp significantly downregulated the expression of proteins and mRNA associated with the TGF-β1/Smad2/3 pathway. …"

Supplementary Material for: Does oXiris Matter? A Comparative Outcome Study in CRRT-Treated Septic ICU Patients حسب figshare admin karger (2628495)

"…Inflammatory markers (CRP, PCT) remained elevated in oXiris patients through day 5, while hemodynamic stabilization (lactate decline, norepinephrine reduction) was more pronounced. Platelet counts decreased in both groups without recovery. Conclusions: Our study demonstrated that patients with sepsis treated using the oXiris filter exhibited significantly higher ICU survival rates, despite higher mechanical ventilation duration and ICU length of stay. …"

Image 4_N1-methylnicotinamide promotes age-related cochlear damage via the overexpression of SIRT1.tif حسب Toru Miwa (8528715)

"…Auditory brainstem response (ABR) thresholds were significantly elevated, and distortion-product otoacoustic emissions (DPOAE) indicated outer hair cell dysfunction. …"

Data Sheet 4_Causality of genetically determined serum metabolites on lower back pain or/and sciatica: a comprehensive Mendelian randomized study.pdf حسب Yi-Ming Ren (555968)

"…Among them, 8 serum metabolites decreased risk of sciatica or/and lower back pain significantly (P < 0.05), and 14 serum metabolites increased risk of sciatica or/and lower back pain significantly (P < 0.05). …"

Table 1_Relationship between high-density lipoprotein cholesterol levels and nutritional risk screening-assessment-intervention: a multicenter cross-sectional study.pdf حسب Qian Li (114642)

"…Additionally, patients with nausea and vomiting, pancreatic insufficiency, severe infection, fever, and hypoalbuminemia decreased HDL-C levels by 0.156 mmol/L, 1.465 mmol/L, 0.403 mmol/L, 0.301 mmol/L, and 0.250 mmol/L, respectively. …"

Data Sheet 1_Congrong Shujing Granules ameliorates mitochondrial associated membranes to against MPP+-induced neurological damage in the cellular model of Parkinson’s disease.pdf حسب Chutian Zhang (10732350)

"…The serum effectively mitigated damage within the MAMs region and reduced both the mitochondrial-Ca²⁺ fluorescence intensity and the expression of the IP₃R-VDAC-MCU complex in MPP⁺-induced neuronal cells. Additionally, it significantly decreased the levels of ROS, the decline in MMP, and apoptosis rates in these cells.…"

Data Sheet 1_Systematic pharmacology-based strategy to investigate the mechanism of beta-sitosterol for the treatment of rheumarthritis.xlsx حسب Xiaodong Wang (66801)

"…The experimental results showed that β-sitosterol could significantly inhibit the excessive proliferation of MH7A cells (p< 0.05). …"

Table 3_Interactions between the intestinal microbiome and host genes in regulating vibriosis resistance in Cynoglossus semilaevis.xlsx حسب Weiwei Zheng (140828)

"…</p>Results<p>Obvious histopathological differences were observed between the resistant and susceptible groups in terms of inflammatory cells infiltration, and tissue dissociation of mucosal layer. 16S rRNA sequencing analysis indicated that Vibrio increased but Stenotrophomonas, Chryseobacterium, Delftia, and Salinivibrio decreased in the susceptible group. Compared to the control group, 1,986 differentially expressed genes (DEGs) were detected in the susceptible group, significantly more than the 310 DEGs found in the resistant group. …"

Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025 حسب Alexandre Berthier (16876311)

"…</p><h3>Impact and implications</h3><p dir="ltr">While the health significance of transient insulin resistance is well established, the molecular processes that occur after such episodes are poorly understood. …"

Image 2_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

"…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"

Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction حسب Yangyi Huang (11859382)

"…</p> <p>The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.…"

Image 1_Modulation of the hepatic RANK-RANKL-OPG axis by combined C5 and CD14 inhibition in a long-term polytrauma model.jpeg حسب Yang Li (7082)

"…Compared to the Nail group, AST serum concentrations were significantly decreased in the Nail+Therapy group after 72 h (p<0.05). …"

Table 1_Effects of perinatal nutrition supplementation and early weaning on serum biochemistry, metabolomics, and reproduction in yaks.docx حسب Kaiyuan Shang (20453966)

"…Lipid transportation molecules apolipoprotein B100 and very low-density lipoprotein of SF and SW yaks were significantly increased along with the decreased lipid mobilization products non-esterified fatty acid and β-hydroxybutyric acid when compared to GF yaks at −15 and 30 d. …"

Understanding discrepancies in soil moisture from SMAP and AMSR2: insights into performance and dry-down behavior حسب Zhiqing Peng (21424474)

"…The analysis shows that SMAP outperforms AMSR2 overall, although the sensing capabilities of both payloads decline with increasing vegetation water content (VWC). Further analysis of global SM dry-down patterns reveals minimal differences in the magnitude of SM dry-down between the two payloads, but slightly larger differences in the effective wilting point. …"

Table 2_Indirect improvement of pepino (Solanum muricatum) productivity via nitrogen fertilizer-mediated microbial and enzymatic stimulation.docx حسب Bingbing Su (16886131)

"…N150 boosted the relative abundance of Bacillus (45.15%), Arthrobacter (72.67%), Sphingomonas (57.55%), and enriched the Mesorhizobium. N75 had slightly positive effects on core genera and nitrogen cycling microorganism. …"

Table 1_Indirect improvement of pepino (Solanum muricatum) productivity via nitrogen fertilizer-mediated microbial and enzymatic stimulation.docx حسب Bingbing Su (16886131)

"…N150 boosted the relative abundance of Bacillus (45.15%), Arthrobacter (72.67%), Sphingomonas (57.55%), and enriched the Mesorhizobium. N75 had slightly positive effects on core genera and nitrogen cycling microorganism. …"

Table 3_Indirect improvement of pepino (Solanum muricatum) productivity via nitrogen fertilizer-mediated microbial and enzymatic stimulation.xlsx حسب Bingbing Su (16886131)

"…N150 boosted the relative abundance of Bacillus (45.15%), Arthrobacter (72.67%), Sphingomonas (57.55%), and enriched the Mesorhizobium. N75 had slightly positive effects on core genera and nitrogen cycling microorganism. …"

Characterisation of conidial length and ascospore production in <i>ΔFgknr4</i> and complemented strains. حسب Erika Kroll (20537020)

"…<p><b>A.</b> Decreased conidial length observed in <i>ΔFgknr4</i>. …"

Data Sheet 1_Dendritic cells in the human vaginal mucosa can direct CD4+ T cell responses by expressing surface OX40L.pdf حسب HyeMee Joo (175770)

"…Neutralizing OX40L with anti-OX40L antibody significantly decreased the frequency of Th2-type CD4⁺ T cells with a reduction of CD4⁺ T cell proliferation, while increasing the frequency of IL - 10-producing CD4⁺ T cell responses. …"

Data Sheet 1_Circulating extracellular vesicles and neutrophil extracellular traps contribute to endothelial dysfunction in preeclampsia.pdf حسب Alex Ramos (16267028)

"…</p>Results<p>VWF, VCAM-1, and ROS expression was significantly higher in cells exposed to PE sera vs. control (12.3 ± 8.1, 3.6 ± 2.3, and 1.8 ± 0.2, respectively, p < 0.05), though significantly lower in cells exposed to depleted PE (dPE) sera (6.1 ± 2.7, 0.7 ± 0.6, and 1.2 ± 0.1, respectively, vs. control, p < 0.05). …"