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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
small decrease » small increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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17521
Table 6_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xlsx
Published 2025“…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …”
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17522
Supplemental file for Training alters cytokine and soluble receptor responses
Published 2025“…Following 1-hour of cycling at their respiratory compensation point, untrained men (n=5) exhibited a significant increase in pro-inflammatory cytokines, including IL-6, TNF-α, IL-1β, CCL2, and VEGFA. …”
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17523
Table 5_Pachymic acid alleviates metabolic dysfunction-associated steatotic liver disease by inhibiting ferroptosis through PPARα.xls
Published 2025“…Introduction<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by excessive lipid deposition in hepatocytes without a history of significant alcohol consumption. Pachymic acid (Pac), a bioactive triterpenoid from Poria cocos, has shown promise in treating MASLD due to its antioxidant and anti-inflammatory capabilities. …”
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17524
Data Sheet 1_Global burden of inflammatory bowel disease in the elderly: trends from 1990 to 2021 and projections to 2051.docx
Published 2024“…The age-standardized incidence rate (ASIR) rose from 8.01 to 8.77 per 100,000, while the age-standardized prevalence rate (ASPR) slightly decreased from 118.14 to 117.29 per 100,000. Death number increased from 14,400 to 33,490, but the age-standardized mortality rate decreased from 3.21 to 2.84 per 100,000. …”
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17525
<b>Contrasting strategies, shared risk: 12-yr nitrogen addition compromises hydraulic safety in young and mature trees via distinct pathways</b>
Published 2025“…We found that, in young trees, N50 decreased soluble sugars in leaves, twigs, and branches, but increased in roots, suggesting a preferential belowground allocation, whereas N20 responses were limited. …”
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17526
Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx
Published 2025“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”
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17527
Image 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.tif
Published 2025“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”
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17528
Table_1_Olfactory dysfunction as an early pathogenic indicator in C. elegans models of Alzheimer's and polyglutamine diseases.xlsx
Published 2024“…We found that the ER unfolded protein response (UPR) is significantly activated in worms expressing Aβ1-42. Activation of the AMPK pathway alleviates olfactory defects and reduces fibrillar Aβ in these worms. …”
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17529
Data Sheet 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.pdf
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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17530
Data Sheet 1_Long-term nitrogen fertilization alters the partitioning of amino acids between citrus leaves and fruits.docx
Published 2025“…As fruits entered the swelling stage, a significant positive correlation emerged between fruiting branch leaves and fruit total N content (R²=0.68), while the R² for leaves on non-fruiting branches dropped to 0.47, indicating a shift in N supply towards leaves on fruiting branches. …”
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17531
Table 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.xlsx
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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17532
Sustainable separation of Xe from the noble gas mixture of Ar, Kr, and Xe using cryogenic distillation and gas hydrates hybrid methods
Published 2025“…From all the simulated processes, a hydrate-hybrid process was found to be the best-performing configuration, achieving the desired separation of xenon with significant energy savings. …”
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17533
Table1_Intranasal dexmedetomidine sedation for EEG in children with autism spectrum disorder.xlsx
Published 2024“…No significant adverse events were reported in either period. …”
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17534
Supplementary file 1_Effect of liraglutide on the dysglycemia, inflammation, and gut microbiota in prediabetic KKay mice.xlsx
Published 2025“…<p>Prediabetes is a significant risk factor for type 2 diabetes mellitus (T2DM). …”
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17535
Video 3_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4
Published 2024“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”
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17536
Oral L-Arginine Treatment Attenuates<i>Cryptococcus neoformans</i>Extrapulmonary Dissemination and Disease Progression
Published 2025“…We found significant depletion of serum L-arginine and its downstream metabolites, accompanied by increased arginase activity in infected tissues, indicating a disrupted metabolic balance. …”
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17537
QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells
Published 2024“…</p> <p>A sustained zero-order drug release was obtained for both the formulations.…”
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17538
Supplementary file 1_Characterization of the gut microbiota in people with different levels of obesity.docx
Published 2025“…Purpose<p>With the evolution of dietary habits, obesity has emerged as a significant global health issue. Numerous studies have demonstrated a close association between obesity and gut microbiota; however, the specific contribution of gut microbiota to varying degrees of obesity remains inadequately understood. …”
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17539
Sustained increase in the levels of pro-inflammatory cytokine and chemokine in the testis correlate with systemic inflammation.
Published 2025“…Pearson coefficient >0.6 was considered a significant correlation.</p>…”
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17540
Image 1_NGF/ERK signaling-mediated epigenetic regulation of neuropathic pain in the cerebrospinal fluid-contacting nucleus.tif
Published 2025“…Statistical analysis was performed, with significance set at a p-value of < 0.05.</p>Results<p>CI induced significant upregulation of NGF in the CSF-CN. …”