CK8 knockdown and ROCK1 inhibitor abolished rTsSPc-reduced TJs expression in Caco-2 monolayers by IFA. by Wen Wen Zheng (17721404)

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PAS staining of intestinal sections from <i>T. spiralis</i>-infected mice pretreated with DAS and Y27632. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of CK8 knockdown blocking the rTsSPc-activated pathway and -reduced TJs expression. by Wen Wen Zheng (17721404)

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IFA, GST pull-down and Co-IP assay of specific binding between rTsSPc and CK8. by Wen Wen Zheng (17721404)

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Transcription and expression levels of CK8 in Caco-2 cells after CK8 gene was knocked down. by Wen Wen Zheng (17721404)

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qPCR and Western blotting of activation of CK8 receptor and RhoA/ROCK1 pathway proteins in Caco-2 cells treated with rTsSPc and IIL ES antigens. by Wen Wen Zheng (17721404)

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CK8 knockdown and ROCK1 inhibitor suppressed rTsSPc-induced disruption of the Caco-2 monolayer and blocked rTsSPc-promoted IIL invasion. by Wen Wen Zheng (17721404)

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Intraperitoneal injection protocol for inhibitors (A), inhibitors DAS and Y27632 reduced intestinal permeability (B) and intestinal adult worm burden (C) of infected mice. by Wen Wen Zheng (17721404)

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HE staining showed that DAS and Y27632 alleviated intestinal inflammation in <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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The ROCK1 pathway inhibitor Y27632 prevented rTsSPc from activating the ROCK1 pathway and reducing TJs expression. by Wen Wen Zheng (17721404)

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qPCR (A-D) and ELISA (E-H) detection of inflammatory cytokines in intestine of <i>T. spiralis</i>-infected mice. by Wen Wen Zheng (17721404)

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National (A) Medicare prescription rates per thousand Part D enrollees and (B) Medicare spending for clozapine gradually decreased for 2015-2020. by Luke R. Cavanah (19022435)

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High-priority areas in methodology and reporting that could be improved. by Brian Critelli (20775838)

Modeling the relationship between cancer level in hemolymph and MarBTN in tank eDNA. by Rachael M. Giersch (22331947)

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S1 Data - by Richard Junior Zapata Dongo (17912565)

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Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

“…Despite FDA approval for two irreversible inhibitors that target the inactive state of KRas^G12C, significant unmet clinical need still exists, and the susceptibility of non-G12C mutants to inactive-state inhibition remains unclear. …”

Table 1_Elevated CO2 decreases micronutrient Zn but not Fe in vegetables – evidence from a meta-analysis.docx by Xiaolin Wang (303612)

“…As expected, we found a significant increase (27%, 95% CI: 14–41%) in vegetable biomass production under elevated CO₂ levels. …”

The sagittal view of T2-weighted Magnetic Resonance Imaging represented a mild decrease in spinal cord diameter without any other lesions at first admission. by Hossein Pourmontaseri (19329565)

Comparison of serum VEGF-A165 concentrations pre-bevacizumab administration in patients with increased VEGF-A post-bevacizumab administration and those with decreased VEGF-A. by Masashi Okawa (8951294)

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Starvation improves locomotory capacity and decreases the number of α-synuclein-YFP aggregates of transgenic <i>C. elegans</i> through LMP-1 dependent mechanism. by María Gallardo-Campos (22170919)