KIF5A-dependent axonal transport deficiency disrupts autophagic flux in trimethyltin chloride-induced neurotoxicity by Mengyu Liu (2890397)

“…<p>Trimethyltin chloride (TMT) is widely used as a constituent of fungicides and plastic stabilizers in the industrial and agricultural fields, and is generally acknowledged to have potent neurotoxicity, especially in the hippocampus; however, the mechanism of induction of neurotoxicity by TMT remains elusive. Herein, we exposed Neuro-2a cells to different concentrations of TMT (2, 4, and 8 μM) for 24 h. …”

Data Sheet 1_Psychological Well-Being in Adults Across the COVID-19 Pandemic: A Two-Year Longitudinal Study.docx by Melanie Ehrler (9759152)

“…Decreasing or consistently low well-being was significantly associated with younger age, limited social support, caregiving responsibilities, concerns about COVID-19 infection, and stress due to pandemic-related changes.…”

Image_2_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…Further, the amplitudes of mAHP were significantly decreased in male BDNF^+/Met mice only, which were mediated by the downregulation of Kcnn2 encoding small conductance calcium-activated potassium channel 2 (SK2). …”

Image_1_A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex.TIF by Kaijie Ma (6065156)

“…Further, the amplitudes of mAHP were significantly decreased in male BDNF^+/Met mice only, which were mediated by the downregulation of Kcnn2 encoding small conductance calcium-activated potassium channel 2 (SK2). …”

Synthesis and biological evaluation of quinoxaline derivatives as ASK1 inhibitors by Xiaorui Han (1401655)

“…<p>Inhibiting apoptosis signal regulated kinase 1 (ASK1) is an attractive strategy for treating diseases such as non-alcoholic steatohepatitis and multiple sclerosis. Here, we report the discovery of a dibromo substituted quinoxaline fragment containing <b>26e</b> as an effective small-molecule inhibitor of ASK1, with an IC₅₀ value of 30.17 nM. …”

Table1_Berberine alleviates ETEC-induced intestinal inflammation and oxidative stress damage by optimizing intestinal microbial composition in a weaned piglet model.docx by Yue Wang (65477)

“…ETEC infection significantly upregulated the expression of genes coding for Nrf2, CAT, SOD1, GPX1, GST, NQO1, HO-1, GCLC, and GCLM in the small intestine of the animals (P<0.05). …”

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…<p dir="ltr"><b>I</b><b>NTRODUCTION</b></p><p dir="ltr">Trimethylamine N-oxide (TMAO) is a small organic molecule found at osmotically-significant concentrations in many marine animal taxa. …”

Data_Sheet_1_The functions and factors governing fungal communities and diversity in agricultural waters: insights into the ecosystem services aquatic mycobiota provide.pdf by Phillip Pham (407350)

“…</p>Discussion<p>Water physicochemical properties, including stream fungicide levels, explained a small proportion of the variation in mycobiota communities, underscoring the significance of unmeasured factors, alongside stochastic community assembly processes. …”

<b>SZC-6</b><b> Promotes Diabetic Wound Healing in Mice by Modulating M1/M2 Macrophage Ratio and Inhibiting MyD88/NF-κB Pathway</b> by 昂 轩 (20139579)

“…We also found that SZC-6 significantly reduced MyD88, p-IκBα, and p-P65 protein levels and inhibited the nuclear translocation of P65 in LPS-treated cells. …”

Image 1_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…One year later, visual acuity of III1 decreased significantly with KC aggravation and corneal opacification. …”

Presentation 1_CD26 as a potential therapeutic target for lung adenocarcinoma.pptx by Wolfgang Jungraithmayr (335920)

“…Here, we analyzed the prognostic significance of CD26 expression and its correlation with epithelial-to-mesenchymal transition (EMT) markers in a large series of patients with non-small cell lung cancer (NSCLC).…”

Table 1_CD26 as a potential therapeutic target for lung adenocarcinoma.docx by Wolfgang Jungraithmayr (335920)

“…Here, we analyzed the prognostic significance of CD26 expression and its correlation with epithelial-to-mesenchymal transition (EMT) markers in a large series of patients with non-small cell lung cancer (NSCLC).…”

Table1_Cover crops lower the dispersal of grapevine foliar pathogens from the ground and contribute to early-season disease management.docx by Gultekin Hasanaliyeva (17752296)

“…In small-scale experiments, we found that cover crops (namely horseradish Armoracia rusticana) were able to (i) reduce the numbers of airborne conidia of Botrytis cinerea (originating from an inoculum source above the soil) escaping the cover canopy by >85% with respect to the base soil and (ii) reduce the number of raindrops impacting the soil by 46%–74%, depending on the cover crop height and rain-originated splash droplets that escaped from the ground by 75%–95%, which reduced splash-borne inoculum. …”

Raw data WB.pdf by Grazia Serino (21164993)

“…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …”

Data_Sheet_1_Optimisation of Lactobacillus fermentation conditions and its application in the fermentation of salt-free sauerkraut.PDF by Wenlun Wang (18863641)

“…Bioproduction was optimal with a culture time of 66 h, starch/water ratio of 1.7% and inoculum of 0.02%, which gave approximately three-fold higher yield than the basal culture medium DeMan-Rogosa-Sharpe medium (MRS). The LAB was used in small-scale industrial experiments. The Dafang LAB significantly enhanced the sensory score of the salt-free sauerkraut products by about 32% compared to the control group. …”

Numerical data underlying the graphs. by Stephanie M. E. Jones (12883691)

“…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”

Sequence of oligonucleotides used in this study. by Stephanie M. E. Jones (12883691)

“…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”

<i>DANCR</i> regulated genes in SK-MEL-28 cells. by Stephanie M. E. Jones (12883691)

“…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”