Data Sheet 1_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.pdf حسب Chaofeng Niu (17746406)

"…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …"

Table 1_Structural and functional characterization of gut microbiota in dyslipidemic patients from high-altitude Tibetan pastoral areas.xlsx حسب Juanjuan Chen (127202)

"…</p>Results<p>Compared with HCs, dyslipidemic patients showed a significant reduction in gut microbial diversity. Specifically, the abundance of beneficial species—including Faecalibacterium prausnitzii, Bifidobacterium adolescentis, Bifidobacterium longum, Bifidobacterium bifidum, and Parabacteroides distasonis—was significantly decreased, while opportunistic pathogens such as Veillonella parvula, V. tobetsuensis, Streptococcus oralis, and Streptococcus mitis were notably enriched. …"

Data Sheet 1_Confronting the anxiety of Generation Z: electroacupuncture therapy regulates oxidative stress and microglia activity in amygdala-basolateral of socially isolated mice... حسب Tong Yin (3576917)

"…</p>Results<p>Our findings reveal that EA treatment significantly mitigates anxiety-like behaviors in mice, correlating with a reduction in NOX2 expression within BLA microglia and decreased levels of reactive oxygen species (ROS). …"

Data Sheet 4_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di... حسب Ying-han Deng (21604157)

"…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…"

DataSheet9_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.docx حسب Yongming Du (807059)

"…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…"

Table 1_Detection of fusion events by RNA sequencing in FFPE versus freshly frozen colorectal cancer tissue samples.xlsx حسب Maxim Sorokin (4379848)

"…We detected no statistically significant difference in the number of chimeric transcripts in FFPE and FF RNAseq profiles. …"

Supplementary Material for: Long-Term Effects of Cognitive Behavioral Therapy on Sickness Absence and Cognitive Functioning in Patients with Stress-Related Disorders: Secondary Res... حسب figshare admin karger (2628495)

"…Results CBT and GHP had comparable effects on SA and cognitive functioning with no significant between-group effects (all p > .05). Analyzing effects across the entire sample, the number of SA days among those with any SA did not significantly change (p = .946) but the likelihood of having any SA decreased significantly by the 1YFU (OR = .92, 95% CI [.87, .96], p < .001). …"

ZNF503-AS2 had predictive value for chemotherapy and immunotherapy in glioma. حسب Yibo Wu (788885)

"…NS, not statistically significant; * <i>P</i> < 0.05; ** <i>P</i> < 0.01; *** <i>P</i> < 0.001.…"

Data Sheet 4_Genome-wide identification of GDPD gene family in foxtail millet (Setaria italica L.) and functional characterization of SiGDPD14 under low phosphorus stress.docx حسب Chaomin Meng (21496829)

"…Under low phosphorus stress, the expression levels of SiGDPD3 and SiGDPD14 significantly increased, while SiGDPD1, SiGDPD5, SiGDPD6, and SiGDPD11 showed significant decreases.To identify the function of SiGDPD14, an over-expressed transgenic Arabidopsis was generated. …"

Spato-temporal changes in land use types. حسب Chao Ma (207385)

"…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …"

Supplementary Materials -Table حسب Shaojie Zhang (20807333)

"…<p dir="ltr">Exposure to hypobaric hypoxia during rapid ascent to high altitudes significantly impacts intestinal barrier function. Goblet cells, as one of the primary cell types in the intestinal mucosa, play a crucial role in maintaining this barrier. …"

Data Sheet 5_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx حسب Shengyou Song (22391068)

"…The TGF-β/Smad signaling pathway plays a significant role in the development and progression of RCC.…"

Supplementary Material for: Light exposure on alertness after wake-up in healthy men: Comparing dim, bright, red and blue light حسب Mekschrat L. (19669585)

"…However, dim vs. bright light and RT did not interact (p = .758). Chronotype was a significant covariate in the interaction of dim vs. bright light and subjective sleepiness (p = .008). …"

Image 5_Uncovering the heterogeneity of NK cells on the prognosis of HCC by integrating bulk and single-cell RNA-seq data.jpeg حسب Jiashuo Li (7865036)

"…Immunohistochemistry showed that HRG expression was decreased in HCC compared to normal tissues, whereas TUBA1B expression was elevated in HCC.…"

DataSheet5_Deficiency of autism susceptibility gene Trio in cerebellar Purkinje cells leads to delayed motor impairments.zip حسب Jinxin Wang (1696837)

"…The decreased expression of Calbindin existed in both 12-week and 20-week old mice compared with control. …"

Image 2_Mitochondrial metabolism is rapidly re-activated in mature neutrophils to support stimulation-induced response.tif حسب Jorgo Lika (21189020)

"…Treatment with these inhibitors also impacts neutrophil redox status, migration, and apoptosis without significantly changing overall bioenergetics.</p>Conclusions<p>Together, these results demonstrate that mitochondrial metabolism is dynamically remodeled and plays a significant role in neutrophils. …"

Table 1_Assessing the impact of risk perception on fisheries performance: a structural equation modeling approach in coastal fisheries.docx حسب Muhammad Mohsin (1335447)

"…Published literature documents such a scenario in the case of Pakistan, which results in a decreased economic contribution to the fisheries sector. …"

Data Sheet 1_Red mite (Panonychus citri) attack amplifies citrus rootstock-driven responses in physiological and biochemical traits, VOC emission, and expression of defence-related... حسب Tommy Rioja (22179742)

"…<p>Citriculture faces significant constraints in expanding into new environments and agroecological zones. …"

Image 3_Exercise intolerance in patients with chronic coronary syndrome: insights from exercise stress echocardiography.tiff حسب Wei-wei Zhu (20349897)

"…An elevated peak EDVi/E/e’ and a decreased ΔSVi are independent risk factors for exercise intolerance in patients with CCS.…"

Table 3_Human umbilical cord mesenchymal stem cells recover chemotherapy-induced premature ovarian failure.xlsx حسب Guojie Ji (21518650)

"…</p>Results<p>After hUC-MSCs therapy, the number of follicles recovered significantly and the atretic follicles decreased significantly. …"