Image 6_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.tif by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Data Sheet 2_Global temporal trends and projections of hepatitis B-related cirrhosis among adolescents and young adults from 1990 to 2035: an analysis based on the global burden of... by Quanwei He (8562327)

“…Background<p>Chronic hepatitis B and cirrhosis pose significant global health threats. Few studies have explored the disease burden and mortality trend of cirrhosis caused by hepatitis B virus infection among adolescents and young adults (AYAs, aged 15–39 years). …”

Data Sheet 1_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Image 1_NET-EN treatment leads to delayed HSV-2 infection, enhanced mucin and T cell functions in the female genital tract when compared to DMPA in a preclinical mouse model.tiff by M. Firoz Mian (10013314)

“…However, DMPA significantly decreased the total number of VT CD4+ and CD8+ T cells and the number of IFN-γ producing CD4 and CD8 T cells and increased the percentage of CD4 and CD8 T cells producing TNF-α compared to untreated mice. …”

Table 1_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.xlsx by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Data Sheet 2_Cell wall modulation by drought and elevated CO2 in sugarcane leaves.xlsx by Alexandre Junio Borges Araujo (12977867)

“…<p>Climate change poses significant challenges to global agriculture, with elevated atmospheric CO2 (eCO₂) concentrations and increased frequency of droughts affecting crop productivity. …”

Data Sheet 1_Analysis of temporal and spatial changes in the global burden of hypertensive heart disease based on data from the Global Burden of Disease study database and future p... by Guoliang Gao (2910503)

“…According to the APC model, the worldwide incidence of hypertensive heart disease is expected to increase from 2022 to 2046, with further decreases in deaths and DALYs.</p>Conclusions<p>This study systematically reveals the increasing trend in the incidence of hypertensive heart disease globally between 1990 and 2021 and confirms the significant impact of sex and socioeconomic development level on its burden. …”

Presentation 1_Genomic analysis, culturing optimization, and characterization of Escherichia bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.... by Mustafa Yesil (20403140)

“…Incubation for 30 min at 4°C−47°C or pH 4–11 had no significant detrimental effect (p > 0.05) on phage infectivity. …”

<b>Beyond Pathogen Identity: Host-Specific Prognostic Markers and mNGS Insights in ICU MDRO Infections</b> by Yi Su (21242279)

“…<p dir="ltr"><b>Background:</b> Multidrug-resistant organism (MDRO) infections in the intensive care unit (ICU) pose a significant threat to global public health, leading to high mortality rates. …”

DataSheet1_IVIG response in pediatric acute-onset neuropsychiatric syndrome correlates with reduction in pro-inflammatory monocytes and neuropsychiatric measures.docx by Isaac Melamed (6291590)

“…The fraction of pro-inflammatory monocytes and dendritic cells decreased from pre-IVIG treatment levels. The proportional reductions were not compensated by increases in total white blood cells; pro-inflammatory monocytes post-IVIG were decreased as a proportion of CD14+ myeloid cells and in absolute number.…”

Image 1_Vitamin D protects spermatogonia and Sertoli cells from heat stress damage by inhibiting NLRP3.pdf by Han Chu (7417343)

“…Phase II, both the siRNA + heat stress and VD + heat stress groups showed decreased apoptosis in spermatogonia and Sertoli cells, lower inflammatory factor levels, increased BCL-2 expression, and decreased NLRP3 expression compared to the heat stress-only group, with statistically significant differences (P < 0.05).…”

Refractive Profiles in Children Receiving School-Based Eye Exams Following Vision Screening from a Large School-Based Vision Program in 2016 to 2022 by Andrew M. Nguyen (20176426)

“…Main outcomes included any refractive error (at least −0.50D myopia, +0.50 hyperopia, 1.00D astigmatism, or 1.00D anisometropia), clinically significant refractive error (CSRE; more severe refractive error with decreased vision), and refractive amblyopia risk (RAR). …”

mRNA levels of CASP family markers (A-E), BCL2 family markers (F-H) and other apoptosis-related markers (I-M) in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after t... by Shanhe Liu (5251313)

“…In LSCs, <i>BCL2</i> mRNA level significantly decreased (p = 0.0102) and <i>CDKN1B</i> level significantly increased using 75 µM CoCl₂ treatment. …”

Structural analysis of wild type and mutated variants of CXCR4. by Bonoshree Sarkar (20469331)

“…The changes in H-bond in the 3D structure of the CXCR4 protein likely have a significant impact on the structure functions of the protein.…”

Data_Sheet_1_A randomized double-blinded study assessing the effect of different doses of transnasal dexmedetomidine on the median effective concentration of ropivacaine for a caud... by Fu Wang (10556)

“…Compared to group IN-NS, the EC50 value of ropivacaine in IN-DEX2 was significantly decreased by 21.4% (p = 0.001), while there was no significant difference between group IN-NS and IN-DEX1 (p = 0.125). …”

Unraveling the Effects of Epigallocatechin-3-gallate on Hepatocellular Carcinoma Cells: A Comparative Analysis of Monolayer vs Multicellular Tumor Spheroids by Mariana dos Reis Simpronio (21876938)

“…The cell culture condition influenced EGCG effects on gene expression and cell viability, with more significant effects in monolayer than in MTS. After 15 days, control MTS showed cellular dissociation, whereas EGCG-treated MTS showed decreased cell viability and no growth. …”

Loss of H2A.Z from transcription start sites was correlated with, but not required for, HU-induced gene activation. by Hilary T. Brewis (11798006)

“…The p-values, generated using hypergeometric probability, indicate if the overlap in each group was significantly greater (red) or less (blue) than excepted by chance (black = non-significant). …”

<b>PathoBiocheModelling to manage Unknowns in Neurodevelopmental Cofactor Disorders</b> by Yuliya Buinitskaya (8680986)

“…Patient C had notable decreased activity of FAD-dependent Isovaleryl-CoA dehydrogenase (IVD). …”

Land use intensity classes standard. by Chao Ma (207385)

“…(ii) The karst habitat quality index decreased from 0.7751 to 0.74085, showing an overall downward trend. …”

Data Sheet 3_Pandan–vanilla rotation mitigates Fusarium wilt disease in vanilla: insights from rhizosphere microbial community shifts.xlsx by Shan Hong (1938337)

“…Crop rotation significantly increased fungal diversity and richness. …”