Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders by Santosh Kumar Rai (22382996)

“…Chronic treatment of MKP10241 in DIO-mice exhibited marked reduction in body weight and feed intake at tested doses, which was associated with decreased blood glucose level, lipid parameters, and body fats. …”

Data Sheet 1_Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease.docx by Xian Liu (191882)

“…The results indicated that Ru/Cur nanodots effectively eliminated various ROS and demonstrated significant therapeutic effects and biocompatibility in IR-AKI mice, reducing markers of kidney function damage, alleviating renal oxidative stress, and decreasing inflammatory cell infiltration. …”

Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx by Lianjie Ruan (22660265)

“…Flow cytometry analysis revealed that carnosine treatment markedly decreased pulmonary infiltration of macrophages and neutrophils. …”

Data Sheet 1_The cultivation of Panax notoginseng enhances the metabolites and microbial network complexity in the soil of Pinus armandii rather than Pinus kesiya.docx by Jingying Hei (20655971)

“…</p>Results and discussion<p>After cultivating Sanqi, the content of total phosphorus, ammonium nitrogen, and total potassium as well as water content and soil pH were significantly increased in P. armandii soil. Moreover, the bacterial and fungal copy numbers, alpha- and beta-diversity, remained unchanged in the soil of P. armandii, but significantly decreased in the soil of P. kesiya following Sanqi planting. …”

Table 6_Transcriptome and metabolome profiling reveal the chlorogenic acid as a resistance substance for rice against the white-backed planthopper Sogatella furcifera (Horváth).xls... by Wenqi Xie (5903936)

“…Exogenous application of CGA to TN1 enhanced its tolerance and antixenosis to WBPH, significantly decreasing WBPH’s survival and mean dry weight. …”

Data Sheet 1_Serum VEGF and ANGPT1 as angiogenesis markers may predict the outcomes of older adults with hip fractures.xlsx by Yuan Yao (31223)

“…Kaplan–Meier survival analysis revealed that low levels of VEGF and ANGPT1 were significantly associated with decreased survival probability. …”

Image1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.PDF by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Table 2_Associations between vitamin K and systemic immune and inflammation biomarkers: a population-based study from the NHANES (2007–2020).docx by Wenjiao Luo (1805428)

“…When the level of vitamin K intake was less than 237.7 mcg/d, RAR showed a significant decreasing trend with the increase of vitamin K. …”

Table 2_Association between lactate/albumin ratio and 28-day mortality in ICU critical patients with coronary heart disease: a retrospective analysis of the MIMIC-IV database.pdf by Ying Liu (18461)

“…Both elevated lactate levels and decreased albumin levels may reflect the body's stress response and inflammatory reaction. …”

Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf by Renfeng Li (126284)

“…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …”

Area of land use types from 2000 to 2020. by Yin Yu (3139023)

“…<div><p>It is significant to research the ecological risk of land use landscape to promote ecological conservation and restoration. …”

Table 1_Mental symptoms in post-COVID syndrome and post-COVID-19 vaccination syndrome: results of a representative population survey.docx by Andreas Czaplicki (21978866)

“…Respondents with only one vaccination reported the highest rate of PCVS symptoms (20.8%), which decreased to 8.9% for those with four or more vaccinations. …”

Supplementary material Figure S2 by Alireza Mani (3341171)

“…For the PD networks (left column), the nodes represent the physiological variables, the edges show significant correlations (p ≤ Bonferroni-adjusted p-value) between the two nodes, and the edge labels display the mean PD values for survivors and non-survivor groups along the significantly correlated variable pair axes. …”

Table_1_Characterization of the microbial communities and their correlations with volatile flavor compounds and physicochemical factors in Bashang suancai, a traditional Chinese pi... by Yuan Liu (88411)

“…The bacterial community diversity decreased significantly following 7 days of fermentation. …”

Supplementary file 1_Prolonged effect of antibiotic therapy on the gut microbiota composition, functionality, and antibiotic resistance genes’ profiles in healthy stool donors.zip... by Ramin Karimianghadim (21288299)

“…No significant increase in clinically important ARGs was detected.…”

Table1_Diverse responses of hypoxia-inducible factor alpha mRNA abundance in fish exposed to low oxygen: the importance of reporting methods.DOCX by Taylor E. Murphy (19800534)

“…<p>Low dissolved oxygen (hypoxia) poses significant challenges to aquatic ecosystems, affecting the behavior, reproduction, and survival of aquatic organisms. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…”

Table1_Dynamics of flavonoid metabolites in coconut water based on metabolomics perspective.xlsx by Mingming Hou (11341656)

“…The total flavonoid content in both types of coconut water exhibited a decreasing trend with developmental progression, but the total flavonoid content in CK was significantly higher than that in W5. …”

Table 8_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx by Jiahao Zhou (11385383)

“…Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.…”

Table 1_Psychometric analysis of the social connectedness instrument.docx by Brian Kelley (1271004)

“…Introduction<p>Social connectedness is decreasing, especially among young adults, which poses a significant public mental and physical health threat globally. …”