يعرض 20,121 - 20,140 نتائج من 23,970 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((step decrease) OR (linear increase)) ))', وقت الاستعلام: 0.69s تنقيح النتائج
  1. 20121

    Data Sheet 1_In silico molecular studies of Phosphinogold(I) thiocarbohydrate complexes: insights into multi-target anticancer mechanisms.docx حسب Alkhair Adam Khalil Mohamed (21529289)

    منشور في 2025
    "…While acetylation decreased binding affinity; it enhanced cellular activity as reported in in vitro studies indicative of the need to balance lipophilicity and binding strength in future ligand design.…"
  2. 20122

    Image 4_Global burden of varicella and herpes zoster across 204 countries, 1990–2021: a temporal trend analysis in the era of the COVID-19 pandemic and projections to 2036.tiff حسب Zilun Wu (18696883)

    منشور في 2025
    "…Mortality and DALYs declined significantly, with age-standardized mortality rates (ASMR) and DALYs rates (ASDR) decreasing by 50.0 and 36.3%, respectively. …"
  3. 20123

    Data Sheet 1_CD19+ B cell depletion: a novel strategy to alleviate ischemic stroke damage.pdf حسب Yu Xu (52257)

    منشور في 2025
    "…Mice subjected to middle cerebral artery occlusion (MCAO) exhibited significant reductions in infarct size and brain edema, prolonged post-MCAO survival, and improved behavioral outcomes following aCD19 Ab treatment. …"
  4. 20124

    Supplementary Material for: Angiopausin® and Angiopoietin: Unveiling New Mechanisms in Rosacea Treatment through Kinetic Erythema Analysis with the AAREA® Algorithm حسب figshare admin karger (2628495)

    منشور في 2025
    "…Reductions in total IEA scores were observed at week 4 (W4; p<0.05) and through W8 to W64 (p<0.001). Decreases in individual scores were also observed for flushing, NTE and edema (W4 to W64: p<0.001), and telangiectasia (W8 to W32; p<0.001). …"
  5. 20125

    Supplementary file 1_Proof-of-concept of a prior validated LC-MS/MS method for detection of N-lactoyl-phenylalanine in dried blood spots before, during and after a performance diag... حسب H. Bauhaus (22335913)

    منشور في 2025
    "…No statistically significant correlations were identified between lac-phe and lactate, glucose as well as anthropometric and respiratory parameters.…"
  6. 20126

    Table 2_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx حسب Rui Jiang (264894)

    منشور في 2025
    "…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …"
  7. 20127

    Table_1_Oxidative stress and inflammation mediate the association between elevated oxidative balance scores and improved sleep quality: evidence from NHANES.docx حسب Qu Zhang (486455)

    منشور في 2024
    "…Sensitivity analyses revealed a significant association between OBS and sleep disorder (p < 0.001).…"
  8. 20128

    Table 1_Probabilistic human health risk assessment of commercially supplied jar water in Gopalganj municipal area, Bangladesh.docx حسب Partha Pratim Brahma (19696279)

    منشور في 2024
    "…<p>Every day, the amount of quality fresh water decreases notably due to contamination of drinking water. …"
  9. 20129

    Table 4_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx حسب Fuxing Lin (7418234)

    منشور في 2025
    "…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …"
  10. 20130

    Image 2_A unique polygenic mouse model of obesity exhibits a distinct immunological profile that may offer protection against systemic inflammation, diabetes, and behavioral impair... حسب Ulrike Gimsa (9730208)

    منشور في 2025
    "…Unlike other mouse lines, DU6 mice do not develop diabetes despite significant obesity. We performed a series of behavioral tests on male mice because obesity is often associated with cognitive and emotional impairment. …"
  11. 20131

    Table 7_Analyze agricultural efficiency and influencing factors base on the three-stage DEA model and Malmquist index.xlsx حسب Lin-Feng Wang (10944843)

    منشور في 2025
    "…TFP peaks at 1.157 (increased by 15.7%) in 2019 and declines to 0.978 (decreased by 2.2%) from 2020 to 2021 due to global economic slowdowns. …"
  12. 20132

    Impact of COVID-19 on early intervention referrals (Zellner et al., 2025) حسب Matthew A. Zellner (12043395)

    منشور في 2025
    "…</p><p dir="ltr"><b>Conclusions: </b>The onset of the pandemic was associated with significant disruption to EI service provision, the magnitude of which varied across states. …"
  13. 20133

    Figure 3 from Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRP... حسب Makito Mizunuma (18950775)

    منشور في 2025
    "…The left shifts of the peaks seen in the sensitive cell lines indicate decreased mitochondrial membrane potential. Carbonyl cyanide-<i>p</i>-trifluoromethoxyphenylhydrazone, an uncoupler of oxidative phosphorylation, was used as the positive control. …"
  14. 20134

    Supplementary file 1_Exploration of the renoprotective effect of Yi-Shen-Hua-Shi granules on db/db mice and the mechanism of podocyte apoptosis based on the GRP78/CHOP signaling pa... حسب Yanmo Cai (22235563)

    منشور في 2025
    "…</p>Results<p>YSHS significantly improved the general status of db/db mice, with a significant reduction in body mass, renal function indices, total cholesterol, triglycerides, and low-density lipoprotein. …"
  15. 20135

    Data Sheet 1_EURAD state-of-the-art report: thermo-hydro-mechanical behaviour of clay buffers at high temperatures.pdf حسب María Victoria Villar (20955281)

    منشور في 2025
    "…The clay mineralogy was significantly preserved. The slight changes observed in the other properties were opposite depending on the heating conditions: in the case of evaporation, the cation exchange capacity, specific surface area, sorption coefficients, and sometimes swelling pressure decreased. …"
  16. 20136

    DataSheet1_Shenshuaikang enema restores the intestinal barrier and microbiota-gut-kidney axis balance to alleviate chronic kidney disease via NF-κB pathway.docx حسب Yan Ye (549400)

    منشور في 2025
    "…Introduction<p>Chronic kidney disease (CKD) is a chronic progressive disease characterized by abnormalities in kidney structure or function caused by variousfactors. It has become a significant public health problem, posing a threat to human health worldwide. …"
  17. 20137

    Quantitative results on WEDU dataset. حسب Dunlu Lu (19964225)

    منشور في 2024
    "…At the same time, the model size was reduced by 9.3%, and the number of model layers was decreased, reducing computational costs and storage requirements. …"
  18. 20138

    Data Sheet 1_The role of oxidative stress in modulating mortality risk across the hypertension control cascade.docx حسب Weihao Liu (4472227)

    منشور في 2025
    "…Q1, HR: 0.82; 95% CI: 0.66–0.87; P < 0.001). A significant interaction was observed between OBS and hypertension control status (P for interaction = 0.017 and 0.026), corroborated by sensitivity analyses (P for interaction = 0.025). …"
  19. 20139

    Table 1_Effect of ticagrelor combined with metoprolol extended-release tablets on cardiac function and clinical prognosis in elderly patients with acute coronary syndrome after per... حسب Lili Wang (104605)

    منشور في 2025
    "…</p>Results<p>The treatment effectiveness rate in the OG was 97.78%, significantly higher than the CG's rate of 77.78% (P < 0.05). …"
  20. 20140

    Table 2_Strategies to support the mental health and well-being of health and care workforce: a rapid review of reviews.docx حسب Cindy E. Frias (20899853)

    منشور في 2025
    "…Health and care workforce report significantly greater levels of job-related burnout and mental health problems, which in turn are associated with poorer patient outcomes, increased medical errors, diminished quality and safety, decreased patient satisfaction, and reduced healthcare efficiency.…"