يعرض 20,141 - 20,160 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((step decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.62s تنقيح النتائج
  1. 20141

    Preventive measures during COVID-19 pandemic. حسب Maryo Baakliny (20910279)

    منشور في 2025
    "…Factors such as age and underlying conditions significantly influenced VE. The findings of this study highlight the effectiveness of the Pfizer-BioNTech (BNT162b2) vaccine in reducing the odds of symptomatic COVID-19, particularly by decreasing the prevalence of key symptoms such as fever, cough, myalgia, and loss of taste or smell. …"
  2. 20142

    Table 1_Statins regulate kinase signaling by causing changes in phosphorylation, rather than through changes in gene expression or direct inhibition: evidence in colorectal cancer.... حسب Francisco Alejandro Lagunas-Rangel (13849122)

    منشور في 2025
    "…In colorectal cancer cell lines, decreased PI3K phosphorylation was at least partially attributable to mevalonate depletion, a known consequence of statin treatment.…"
  3. 20143

    Presentation 1_Gallic acid attenuates diabetic cardiomyopathy by inhibiting ferroptosis and protecting mitochondria via the TSPO/FTMT pathway.pptx حسب Chenchao Zou (22768010)

    منشور في 2025
    "…Purpose<p>Diabetic cardiomyopathy (DCM), which is diabetes mellitus-induced cardiomyopathy, significantly elevates the risk of heart failure and sudden cardiac death. …"
  4. 20144

    Image 2_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.tif حسب Yuanbing Zhu (20538638)

    منشور في 2025
    "…Differential gene expression and immune infiltration analysis showed that upstream transcription factors, including Forkhead box P3 (FOXP3), were significantly disrupted. In vitro cytology experiments, the results indicate that SIRT1 is activated in LPS induced inflammation, subsequently perturbing the Treg/Th17 immune balance axis. …"
  5. 20145

    Supplementary file 1_Akkermansia muciniphila alleviates cognitive impairment and neuroinflammation induced by blunt chest trauma.docx حسب Lin Liu (74495)

    منشور في 2025
    "…AKK also modulated the expression of metabolites linked to neuroinflammation and cognitive function, upregulated BDNF and TrkB, and decreased IBA1, suggesting it enhances cognitive function by modulating neuroinflammation and the BDNF/TrkB signaling pathway.…"
  6. 20146

    Table 4_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"
  7. 20147

    Table 1_Minimally invasive versus open surgery in uterine serous carcinoma: impact on recurrence and survival in a multicenter cohort.xlsx حسب Yi Fang (287944)

    منشور في 2025
    "…Hypertension was also associated with decreased OS (HR = 2.06, 95% CI: 1.11–3.81, P = 0.022).…"
  8. 20148

    Supplementary Material for: Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review حسب Ambarsari C.G. (16518681)

    منشور في 2025
    "…Nevertheless, mortality rates decreased significantly in the latter half of the twentieth century due to effective perioperative blood pressure (BP) management. …"
  9. 20149

    Image 3_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

    منشور في 2024
    "…<p>Keloid scarring is a fibroproliferative disease of the skin, which can significantly impact one’s quality of life through cosmetic concerns, physical discomfort (itchy; painful), restricted movement, and psychological distress. …"
  10. 20150

    Supplementary file 1_Model-based multi-year P flow analyses and strategies for sustainable food chain management in Changzhou city at China's Taihu Basin.docx حسب Zheng Guo (14989)

    منشور في 2025
    "…Besides, urine diversion and waste incineration scenarios significantly decreased P accumulation in the food chain. …"
  11. 20151

    Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke حسب Yike Wu (20982007)

    منشور في 2025
    "…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …"
  12. 20152

    Image_2_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.jpg حسب Živa Frangež (5946392)

    منشور في 2025
    "…Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …"
  13. 20153

    Data Sheet 1_Distribution of different plant life forms on tropical islands: patterns and underlying mechanisms.docx حسب Chengfeng Yang (3333489)

    منشور في 2025
    "…Introduction<p>Island biogeography theory posits that both island area and isolation significantly influence species distribution patterns and community structure. …"
  14. 20154

    Table_1_ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1.docx حسب Živa Frangež (5946392)

    منشور في 2025
    "…Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …"
  15. 20155

    Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf حسب Li Yang (6520)

    منشور في 2025
    "…</p>Results<p>From 1990 to 2021, The ASR of all-cause DALYs in China decreased by 35.94% overall and by 33.99% among individuals ≥65 years. …"
  16. 20156

    Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf حسب Qi Dong (119569)

    منشور في 2025
    "…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …"
  17. 20157

    Data Sheet 1_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

    منشور في 2025
    "…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"
  18. 20158

    Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf حسب Qiao Ma (136536)

    منشور في 2025
    "…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …"
  19. 20159

    Data Sheet 1_The CaSBP11 gene functions as a negative regulator in pepper drought stress.doc حسب Huai-Xia Zhang (8493453)

    منشور في 2025
    "…Our results revealed that drought conditions significantly upregulated CaSBP11 expression, whereas ABA treatment suppressed it. …"
  20. 20160

    Health Risks of Low-Dose Dietary Exposure to Triphenyl Phosphate and Diphenyl Phosphate in Mice: Insights from the Gut–Liver Axis حسب Jing Cao (287196)

    منشور في 2025
    "…TPHP intake affected the levels of short-chain fatty acids and bile acids in the gut, enhancing the production of 29 medium- and long-chain fatty acids in the liver by 3.72-fold and significantly increasing hepatic lipid and cholesterol levels. …"