يعرض 19,421 - 19,440 نتائج من 21,342 نتيجة بحث عن '(( significant decrease decrease ) OR ( significant ((step decrease) OR (mean decrease)) ))', وقت الاستعلام: 0.41s تنقيح النتائج
  1. 19421

    Table 1_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.do... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"
  2. 19422

    Image 2_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

    منشور في 2024
    "…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"
  3. 19423

    Data Sheet 1_Aloe-emodin plus TIENAM ameliorate cecal ligation and puncture-induced sepsis in mice by attenuating inflammation and modulating microbiota.docx حسب Jingqian Su (666622)

    منشور في 2024
    "…Combining AE and TIE significantly enhanced survival rates, and reduced inflammation and bacterial load in septic mice, indicating potent antimicrobial properties. …"
  4. 19424

    Table 1_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

    منشور في 2025
    "…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"
  5. 19425

    Table 4_A putative glucose-1-phosphate thymidylyltransferase is required for virulence, membrane-associated mechanisms, and tolerance to external stresses in Acidovorax citrulli.xl... حسب Junhyeok Choi (14078586)

    منشور في 2025
    "…Notably, the mutant was highly susceptible to multiple stress conditions—including ethylenediaminetetraacetic acid, acetic acid, cupric chloride, sodium dodecyl sulfate, and pH stress—as indicated by significantly decreased OD values or colony forming units (CFUs) compared to the wild type. …"
  6. 19426

    Table 4_Plasma exosomal miRNA expression and gut microbiota dysbiosis are associated with cognitive impairment in Alzheimer’s disease.docx حسب Kaihao Lin (13016658)

    منشور في 2025
    "…</p>Results<p>Four exosomal miRNAs and 14 microbiota taxa, which exhibited differential expression and abundance, respectively, in comparison between AD group and normal cognition group, were identified to be significantly associated with MMSE scores. Notably, the abundance of potential probiotics, including Faecalibacterium prausnitzii, Roseburia intestinalis and Roseburia inulinivorans, which was decreased in AD patients, exhibited positive correlations with specific exosomal miRNAs: Roseburia intestinalis correlated with miR-3120-3p and miR-6529-5p; Roseburia inulinivorans correlated with miR-3120-3p, miR-6529-5p and miR-124-3p; Faecalibacterium prausnitzii correlated with miR-3120-3p.…"
  7. 19427

    Image_1_Untargeted metabolomics reveals the alteration of metabolites during the stewing process of Lueyang black-bone chicken meat.pdf حسب Ling Wang (56577)

    منشور في 2024
    "…During the heating process, the abundances of Ser, Ala, Tyr, niacinamide, galactose, guanosine 3′-monophosphate and inosine 5′-monophosphate in chicken meat significantly decreased and were partially dissolved in the soup. …"
  8. 19428

    Table 1_Exploring the antiviral potential of shikimic acid against Chikungunya virus through network pharmacology, molecular docking, and in vitro experiments.docx حسب Jialiang Xin (6941207)

    منشور في 2025
    "…<p>Chikungunya virus (CHIKV) is an arbovirus that can lead to chronic arthritis and significantly diminish the quality of life of patients. …"
  9. 19429

    Image_1_Notoginsenoside R1 Protects Against Diabetic Cardiomyopathy Through Activating Estrogen Receptor α and Its Downstream Signaling.JPEG حسب Bin Zhang (64682)

    منشور في 2025
    "…In vitro experiments revealed that pretreatment with NGR1 significantly decreased AGEs-induced mitochondria injury, limited an increase in ROS, and reduced apoptosis in H9c2 cells. …"
  10. 19430

    Image 1_CT angiography-derived three-dimensional pulmonary vein topography is related to the outcome after cryoballoon ablation.tiff حسب Martin Saal (21267734)

    منشور في 2025
    "…The number of occlusion attempts in the right inferior PV was significantly higher in the PVI failure group indicating a technical more complex balloon occlusion. …"
  11. 19431

    MiR-15a-5p Knockdown up-Regulated ABCB1 Expression and Abated HNSCC Progression via the NF-κB Signaling Pathway حسب Jing Liu (38537)

    منشور في 2024
    "…</p> <p>ATP binding cassette transporter 1 (ABCB1) had the highest mutation frequency and multiple mutation types in HNSCC, and the decreased ABCB1 was significantly related to better prognosis of HNSCC patients. …"
  12. 19432

    Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx حسب Raneen Sawaid Kaiyal (20418824)

    منشور في 2024
    "…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…"
  13. 19433

    Table 2_Global, regional and national burden of traumatic amputations from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021.docx حسب Baixing Wei (21461966)

    منشور في 2025
    "…However, the change in age-standardized rates from 1990 to 2021 declined significantly. The association between the Socio-demographic Index (SDI) and the burden of amputations in 2021 was not linear. …"
  14. 19434

    Table 1_Outcomes after liposuction-based treatment of lymphedema: a systematic review and meta-analysis.pdf حسب Junzhe Chen (5729912)

    منشور في 2025
    "…Combined approaches achieved slightly lower reductions (87.31%), but significantly decreased compression dependence, improved lymphatic function, and enhanced QOL. …"
  15. 19435

    Image 1_Exploring the role of LOX family in glioma progression and immune modulation.jpeg حسب Chen Liu (75209)

    منشور في 2025
    "…</p>Results<p>The LOX family was significantly upregulated in low-grade gliomas and strongly associated with poor clinical outcomes. …"
  16. 19436

    Table2_Transcriptomic profiling with vascular tension analyses reveals molecular targets and phenotypes in preeclamptic placental vasculature.xlsx حسب Eryun Zhang (20172057)

    منشور في 2024
    "…Several hub genes, including ELMO1, YWHAE, and IL6ST, were significantly reduced in the placental vessels in preeclampsia. …"
  17. 19437

    Image 1_COVID-19 mitigates the response to TKIs in patients with CML via the inhibition of T-cell immunity.pdf حسب Na He (295300)

    منشور في 2024
    "…Our results showed that effector CD8+ T (Teff) cells were significantly downregulated while naïve CD8+ T cells or Treg cells were obviously upregulated in P210-elevated CML patients after contracting COVID-19 compared to that in P210-unchanged or decreased CML patients. …"
  18. 19438

    Interplay of <i>Mycobacterium abscessus</i> and <i>Pseudomonas aeruginosa</i> in experimental models of coinfection: Biofilm dynamics and host immune response حسب Víctor Campo-Pérez (21267009)

    منشور في 2025
    "…Coinfections in bronchial epithelial cells significantly decreased cell viability, whereas in <i>G. mellonella</i>, coinfections induced lower survival rates than individual infections. …"
  19. 19439

    Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff حسب Emmrich Wakeford (21249104)

    منشور في 2025
    "…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …"
  20. 19440

    Data Sheet 1_Cerebrospinal fluid and serum cytokine profiles in severe viral encephalitis with implications for refractory status epilepticus: a retrospective observational study.d... حسب Peipei Huang (3623933)

    منشور في 2025
    "…CSF IL-6 and IL-8 levels were significantly elevated in the RSE group compared to patients without seizures and with controlled seizures, decreasing gradually and independently of serum cytokine levels. …"