Image 3_Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in... by Xingke Song (21372995)

“…</p>Results<p>Behavioral tests demonstrated that LPS-induced rats exhibited significant depressive-like behaviors, including reduced sucrose preference, decreased activity levels in the open field, and restricted exploratory behavior in the elevated plus maze. taVNS intervention significantly alleviated these depressive-like behaviors. …”

Table 1_Burn inhalation injury and intubation with dexamethasone-eluting endotracheal tubes modulate local microbiome and alter airway inflammation.xlsx by Gabriela Gonzales (19756103)

“…Inflammatory markers IFN-γ, IL-4, and IL-1β were elevated in dexamethasone-ETT groups at 3 days, then decreased by 7 days. Macrophage markers CD86 and CD206 were significantly greater in dexamethasone groups compared to regular ETT groups at 7 days (p = 0.002 and p = 0.0213, respectively). …”

Table 2_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx by Jiamin Chen (388522)

“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”

Table 3_The boundaries between PML and PML-IRIS: difficult to define, pathology may predict.docx by Jiamin Chen (388522)

“…</p>Results<p>Notably, 63.2% (12/19) of them had blood CD4+ T-cell counts < 200 cells/μl, and 36.8% (7/19) had ≥ 200 cells/μl. 52.9% (9/17) of the patients had elevated CSF protein, 5.3% (1/19) had decreased CSF glucose. Statistical analysis revealed significant correlations between mass effect and both blood CD4+ T-cell counts (P = 0.022) and CSF protein levels (P < 0.001). …”

Table 3_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... by Yuan Li (67017)

“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”

Table 1_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analysis.x... by Yuan Li (67017)

“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”

Data Sheet 1_Increased accrual of diverse patient populations in oncology phase I clinical trials at the University of Colorado Cancer Center.docx by Ahmed Alsafar (21716735)

“…However, in the most common cancer type, colorectal cancer, higher ADI scores were associated with decreased median PFS and OS.</p>Conclusion<p>The interventions resulted in an increase in accrual of non-English speaking patients, however, there was not yet a significant change in overall race and ethnicity. …”

Figure 4 from PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma by Gwendolyn M. Cramer (16964052)

“…However, the levels of DX5+ (NKT cells) decreased slightly but significantly in TI (<i>P</i> = 0.017). …”

Propagation prediction of asymmetrically originated fractures by use of displacement discontinuity method by Qingquan Li (747754)

“…As the fluid power law index decreases, the fluid viscosity is significantly reduced due to the effect of shear thinning, causing the asymmetrically originated fractures to propagate parallel to the direction of maximum principal stress. …”

Table 1_The expression regulation of recA gene and bacterial class 2 integron-associated genes induced by antibiotics.docx by Jinglu Ye (18768758)

“…Continuous induction leads to sustained upregulation of these genes, which stabilizes or slightly decreases upon reaching a plateau. However, the capacity of different drugs to induce expression varies significantly. …”

Data Sheet 1_Global, regional, and national epidemiology of Intracerebral Hemorrhage among women of childbearing age (1990–2021): incidence, mortality, DALYs, and risk factor analy... by Yuan Li (67017)

“…Background and Objectives<p>Intracerebral Hemorrhage (ICH) is a serious cerebrovascular condition that poses a significant health risk to women of childbearing age (WCBA) globally. …”

Table 5_Nusinersen for children with type I spinal muscular atrophy: 4 years’ clinical experience in Turkish cohort.docx by Ömer Bektaş (13827139)

“…Ventilator and gastrostomy requirements decreased in the early treated cohorts. Adverse events were rare, with one discontinuation due to hydrocephalus. …”

Table 2_Bioelectrical impedance vector analysis in older adults: reference standards from a cross-sectional study.docx by Francesco Campa (20997323)

“…</p>Results<p>New reference values for older adults were established. Significant differences (p < 0.001) in R/H and phase angle were observed when older adults were grouped by age categories, while R/H, Xc/H, and phase angle showed significant differences among ALSM/H² tertiles. …”

Data Sheet 1_Global, regional, and national burden of interstitial lung disease in middle-aged and older adults from 1990 to 2021 with projections to 2050: a systematic analysis of... by Long Chen (315739)

“…Joinpoint regression analysis revealed that while ASPR and ASIR increased from 1990 to 2010 but subsequently decreased from 2010 to 2021, conversely, ASDR and DALYs increased from 1990 to 2011 before declining after 2011, frontier analysis highlighted Canada, Ireland, the United States, Japan, and the United Kingdom as nations with significant improvement potential. …”

Table 1_Spatio-temporal patterns and determinants of persistent catastrophic health expenditure in China: evidence from the China Family Panel Studies.docx by Man-ci Zhou (22776350)

“…Background<p>The escalating out-of-pocket medical expenses pose a significant threat to the financial stability of households worldwide. …”

Supplementary file 1_Impacts of climate change on chronic respiratory health in Ethiopia: a systematic review and meta-analysis.docx by Zewudu Andualem (8602434)

“…Study design influenced prevalence estimates, with cross-sectional studies reporting higher rates (46%) than case–control studies (14%). Significant heterogeneity (I² = 99%, p < 0.001) was observed across studies.…”

Data Sheet 1_Resistance characteristics of culture-positive tuberculosis from 2015 to 2022.xlsx by Zhenzhen Wang (250368)

“…The overall TB resistance rates were significantly higher in the main urban areas. During the study period, the proportion of mono-resistance tuberculosis (MR-TB), multidrug-resistant tuberculosis (MDR-TB) and polydrug-resistant tuberculosis (PDR-TB) decreased by 59.2% (12.9–5.3%), 40.3% (12.4–7.4%), and 68.3% (6.9–2.2%), respectively. …”

Table 4_Isowighteone attenuates vascular calcification by targeting HSP90AA1-mediated PI3K-Akt pathway and suppressing osteogenic gene expression.xls by Yuanxi Mo (22090130)

“…(F. hispida, Moraceae), has demonstrated significant anti-inflammatory properties in prior studies. …”

Data Sheet 1_Disproportionality analysis of adverse events associated with pacritinib: a real-world study based on FDA Adverse Event Reporting System (FAERS) database.docx by Huiling Zhang (396342)

“…Common preferred terms were identified, including diarrhea, fatigue, death, nausea, platelet count decreased, and hemoglobin decreased. Notably, 26 off­-label AEs were also identified.…”

Opportunistic analysis of clinically actionable DPYD gene variants in a germline testing cohort in India by Rajdeep Raha (22056304)

“…</p> <p>A total of 95 individuals (5.3%) carried at least one decreased or no function DPYD variant, indicating a significant prevalence of clinically actionable genotypes in this Indian cohort. …”