Table 1_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.docx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Data Sheet 1_Gram-positive enhancer matrix delivering FVpE via M cell targeting elicit protective mucosal and adaptive immune responses against Helicobacter pylori infection.doc حسب Furui Zhang (3181935)

"…Finally, H. pylori-infected mice treated with GEM-SAM-FVpE can significantly reduce the colonization of H. pylori in gastric tissue while also decreasing gastric mucosal damage.…"

Table 2_Bacteroides ovatus-derived N-methylserotonin inhibit colorectal cancer via the HTR1D-mediated cAMP-PKA-NF-κB signaling axis.xlsx حسب Jikai He (11888466)

"…</p>Results<p>(1) CRC patients showed significantly increased metabolic pathways including glycolysis, methane metabolism, beneficial amino acid degradation, and linoleic acid degradation, along with significantly decreased B.o abundance and NMS levels, which were positively correlated; (2) NMS significantly inhibited CRC cell proliferation, migration, and invasion, while promoting apoptosis; (3) Combined treatment with B.o and orange fiber or NMS alone reduced tumorigenesis and improved intestinal barrier function; (4) Mechanistic studies revealed that these effects could be mediated through downregulation of 5-hydroxytryptamine receptor 1D (HTR1D) expression and inhibition of the cAMP/PKA/IκBα/NF-κB pathway; (5) The treatments optimized gut microbiota structure and metabolite composition.…"

Exogenous jasmonic acid alleviates Cu-induced damages in guinea grass by enhancing photosynthesis, antioxidant enzyme activity and modifying associated metabolites حسب Jian Ren (175424)

"…The results indicated that Cu stress significantly reduced superoxide dismutase (−51.2%) and peroxidase (−38.0%), chlorophyll content, net photosynthetic rate (<i>Pn</i>), and led to decreases in leaf length, width, plant height, and biomass (−49.7%). …"

DataSheet1_Synergistic effects of SAP and PGPR on physiological characteristics of leaves and soil enzyme activities in the rhizosphere of poplar seedlings under drought stress.pdf حسب Dawei Jing (18515707)

"…Compared with normal watering, the DR treatment significantly decreased the contents of dehydroascorbate (DHA; 19.08%), reduced glutathione (GSH; 14.18%), oxidized glutathione, soluble protein (26.84%), indoleacetic acid (IAA; 9.47%), gibberellin (GA) and zeatin (ZT), the IAA/abscisic acid (ABA), GA/ABA, ZT/ABA and (IAA+GA+ZT)/ABA (34.67%) ratios in leaves, and the urease and sucrase activities in the rhizosphere soil. …"

Table 4_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls حسب Genet Atsbeha (17595417)

"…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …"

The timeline of the experiment. حسب Shadi Nazarizadeh (20108029)

"…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …"

Data Sheet 1_Impact of digital health on Type 2 diabetes management: a randomised controlled trial of the ‘TreC Diabete’ platform (TELEMECHRON Study).docx حسب Alexia Giovanazzi (16816139)

"…At 12 months, the median change in HbA1c levels did not differ significantly between groups. Regarding app usage, data entries decreased significantly from the first quarter to the second quarter but subsequently stabilised (p = 0.001). …"

Table 1_Investigating the Gut Microbiota Profile in Prehypertensive Individuals Exhibiting Phlegm-Dampness Constitution.docx حسب Ning Yu (358970)

"…</p>Results<p>At the phylum level, the abundance of Bacteroidetes decreased in the PDC group compared with the NPDC group. …"

Table 2_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx حسب Zeyi Lv (19344178)

"…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …"

Table_1_Baicalin enhances antioxidant, inflammatory defense, and microbial diversity of yellow catfish (Pelteobagrus fulvidraco) infected with Aeromonas hydrophila.DOCX حسب Pupu Yan (19710400)

"…Furthermore, baicalin significantly inhibited biofilm formation and facilitated the release of intracellular proteins (P < 0.05). …"

Supplementary file 1_Assessing pteropod shell dissolution to advance ocean monitoring techniques: a methods comparison of SEM, CT, and light microscopy.zip حسب Bryce E. Koester (21473132)

"…For L. retroversa, LDX was also significantly correlated to SEM maximum dissolution type. …"

Image 3_Global, regional, and national burden of ischemic stroke in older adults (≥60 years) from 1990 to 2021 and projections to 2030.jpeg حسب Shuting Hua (21264785)

"…</p>Conclusion<p>The global burden of ischemic stroke has significantly decreased, particularly in high-SDI regions with abundant healthcare resources. …"

Table 5_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls حسب Genet Atsbeha (17595417)

"…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …"

Supplementary file 1_Effects of microbial organic fertilizers on soil microbial communities and physicochemical properties in tobacco cultivation.docx حسب Shengli Wang (4318522)

"…</p><p>Results and Discussion: The results indicated that MOF reduced the uptake of ammonium nitrogen by tobacco at different growth stages, promoted the dispersion of the microbial community, and significantly altered the soil microbial community structure. …"

Table 6_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls حسب Genet Atsbeha (17595417)

"…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …"

S1 Raw data - حسب Shadi Nazarizadeh (20108029)

"…EEG power in the HINS group decreased significantly compared to other experimental groups (p<0.05). …"

Image 4_NLRP3 deficiency aggravated DNFB-induced chronic itch by enhancing type 2 immunity IL-4/TSLP-TRPA1 axis in mice.tif حسب Si-Ting Huang (5591432)

"…Inhibition of TRPA1 or administration of recombinant IL-18 significantly reduced DNFB-induced itch behavior in Nlrp3-/- mice. …"

Table 2_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.doc حسب Genet Atsbeha (17595417)

"…<p>Fungal diseases, such as stripe rust, are major bottlenecks in Ethiopian wheat production. They can significantly reduce yields and impact regional food security. …"

Table 5_Quercetin exhibits multi-target anti-allergic effects in animal models: a systematic review and meta-analysis of preclinical studies.docx حسب Zeyi Lv (19344178)

"…</p>Results<p>The meta-analysis showed that quercetin significantly decreased the expression of total IgE, OVA-specific IgE, and histamine, and suppressed the infiltration of eosinophils, macrophages, and lymphocytes. …"