Image 1_Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice.pdf by Yan Gong (103494)

“…Additionally, MA notably inhibited osteoclast activity, as evidenced by a decrease in the number of osteoclasts and a significant suppression of F-actin formation. …”

Co-immunoprecipitation and BiFC experiments related to Abd-B and Exd interaction. by Jesús R. Curt (20553231)

“…Protein present in the co-IPs is indicated above the gels. There is a significant decrease in the amount of the Abd-B^W protein captured on the resin when compared to the Abd-B wildtype protein (24%), while Exd remains almost unchanged (2%). …”

List of HipSci cell lines used in the study. by Sara Cuvertino (18892069)

“…In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. Our analysis reveals significant enrichment of differentially downregulated genes in areas containing putative enhancer regions with H3K4me1 loss. …”

List of DEGs from iPSC analysis. by Sara Cuvertino (18892069)

“…In contrast with the epigenomic changes, the number of DEGs decrease as differentiation progresses. Our analysis reveals significant enrichment of differentially downregulated genes in areas containing putative enhancer regions with H3K4me1 loss. …”

Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf by Gufeng Gao (16835753)

“…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …”

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... by Aya Miyagawa-Hayashino (386487)

“…The changes in protein levels of RhoA and ROCK1 were not significant. *<i>P</i><0.05 by one-way ANOVA, Dunnett’s multiple comparison test compared with DMSO control in (A) and (B). …”

Table 1_Global burden of reported lower respiratory system fungal infection.docx by Zheng Wang (25883)

“…Key indicators included age-standardized disability-adjusted life-year (ASDR) and age-standardized mortality rates (ASMR).</p>Results<p>On a global scale, the burden of lower respiratory fungal infections decreased significantly from 1990 to 2021, with a decline in mortality rates. …”

Supplementary file 1_Distance and orientation of hydrophones influence the received soundscape in shallow coral reefs.docx by Juan Carlos Azofeifa-Solano (10983207)

“…</p>Discussion<p>These findings indicate that sensor directivity significantly influences the received soundscape, introducing a potential methodological bias within and across acoustic datasets. …”

Table 1_Effectiveness of conversational script optimization by intelligent consultation robots on daily work efficiency in vaccination clinics.docx by Bei Zhou (5219792)

“…</p>Results<p>As the scripts evolved, there was a notable increase in automated response rates and a decrease in human support transfers. …”

Data Sheet 1_Palmitoylethanolamide causes dose-dependent changes in brain function and the lipidome.docx by Shreyas Balaji (20344923)

“…There was an inverse dose–response for negative BOLD suggesting a decrease in brain activity affecting the prefrontal ctx, sensorimotor cortices, basal ganglia and thalamus. …”

Table 1_Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat.docx by Shellye González-González (20517563)

“…In contrast, DLAN male offspring exhibited a significant decrease in social play behavior compared to LD animals, which was associated with higher numbers of microglia in the NAc that had more ramified morphology. …”

ALKBH5 induces macrophage activation to promote renal fibrosis via Retnla by Long Zheng (694761)

“…Macrophage-specific ALKBH5 knockout could significantly alleviate renal fibrosis in UUO mice and decrease the infiltration of macrophages in the kidneys. …”

Data Sheet 1_Antiretroviral therapy initiated during acute infection in women with HIV-1 clade C reduces anti-Tat antibody production and lowers CD8+ T cell activation.pdf by Thandeka I. Kubheka (21562460)

“…</p>Results<p>The data showed that anti-Tat IgG and IgM titres had decreased significantly after 12 months of treatment (p=0.0001) with no correlation between anti-Tat IgA, IgG or IgM and CD4+ T-cell counts (r= -0.09 to 0.2, p>0.05). …”

Table 3_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Table 7_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Image 1_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.jpg by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Table 8_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”

Inclusion and exclusion table. by Tong-jie Yang (20939652)

“…<div><p> Background </p><p>Computed tomography (CT) Hounsfield Units (HU) offer valuable insights into the changes in bone and soft tissue densities, playing a crucial role in the diagnosis and management of various proximal femur conditions. …”

Table 1_Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation.docx by Weilong Li (8778146)

“…Background<p>Immune rejection represents a significant barrier to transplantation, especially in the context of xenotransplantation. …”

Table 4_NK cell-derived extracellular vesicles enhance cytotoxicity and immune cell recruitment in non-small cell lung cancer.xlsx by Joanna Palade (17712960)

“…Next, we examined the functional capabilities of patient NKEVs in organoid structures derived from primary tumor cells, finding that exposure to patient NKEVs resulted in a 40-45% decrease in organoid viability, and significantly lowered the cisplatin dose required to elicit cytotoxicity. …”