Showing 3,361 - 3,380 results of 21,342 for search '(( significant decrease decrease ) OR ( significant ((teer decrease) OR (we decrease)) ))', query time: 0.51s Refine Results
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    Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

    Published 2025
    “…Despite FDA approval for two irreversible inhibitors that target the inactive state of KRas<sup>G12C</sup>, significant unmet clinical need still exists, and the susceptibility of non-G12C mutants to inactive-state inhibition remains unclear. …”
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