Table 2_Burden of hypertensive heart disease attributed to metabolic factors from 1990 to 2021 at global, regional, and national levels: an analysis of the global burden of disease... by Bo Peng (273834)

“…</p>Results<p>In 2021, deaths and DALYs due to HSBP and high BMI significantly increased compared to 1990. However, the ASMR for HSBP-related HHD [EAPC: −0.68; 95% confidence interval (CI): −0.77 to −0.58] and ASDR (EAPC: −0.90; 95% CI: −0.99 to −0.80) showed a decreasing trend, while the ASMR for BMI-related HHD (EAPC: 0.33; 95% CI: 0.27–0.39) and ASDR (EAPC: 0.15; 95% CI: 0.10–0.21) exhibited an increasing trend. …”

Data Sheet 4_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

Image2_Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren’s syndrome via suppression of the CX3CL1/CX3CR1 axis.tif by Zi Yang (276531)

“…The gene expression levels of cytokines and chemokines, including Ccl12, Ccl3, Il1r1, Ccr2, Cx3cr1, Il7, Mmp2, Mmp14, Il1b, and Il7, significantly decreased after treatment with MYDGF, as determined by RNA sequencing. …”

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…In the MTX+Cur group, atretic follicle count decreased (<i>p</i> < 0,05), however, primordial follicle count increased (<i>p</i> < 0,01). …”

Data Sheet 3_The characteristics of auditorial event-related potential under propofol sedation associated with preoperative cognitive performance in glioma patients.docx by Xinxin Wang (134010)

“…Compared to that in the non-MCI group, the average amplitude of the MMN component evoked by the novel stimulus significantly decreased during the recovery period in the MCI group (−3.895 ± 1.961 μV vs. -1.617 ± 1.831 μV, p = 0.003). …”

Changes in dorsal-ventral patterning of CA1 in COUP-TFI mutant hippocampus. by Ching-San Tseng (6252566)

“…The Dcn/Wfs1 ratio was significantly decreased in the cKO and increased in the cTG. …”

Data Sheet 3_Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by Ca2+ flux through MAMs.pdf by Yufei Li (433737)

“…YQHX also restored MAMs morphology, decreased mPTP opening and Ca²⁺ levels, and reversed GRP75 downregulation blocked by MKT-077 under oxygen-glucose deprivation.…”

Image2_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental vali... by Wenyuan Chen (1770583)

“…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …”

RtcB cooperates with its cofactor Archease to promote axon regeneration. by Qin Wang (109812)

“…(D and E) Compared with <i>RtcB</i>^<i>1-4B</i> or <i>Archease</i>^<i>PB</i> heterozygotes, axon regeneration is significantly decreased in <i>RtcB</i> and <i>Archease</i> transheterozygotes. …”

DataSheet1_Comprehensive analysis of Hibisci mutabilis Folium extract’s mechanisms in alleviating UV-induced skin photoaging through enhanced network pharmacology and experimental... by Wenyuan Chen (1770583)

“…In vitro experiments showed that EHMF significantly reduced UV-induced inflammatory factors in HaCaT cells and improved cell survival rates. …”

Video 1_Kininogen enhances seizure susceptibility in mice possibly through bradykinin-induced modulation of calcium transients in glutamatergic and GABAergic neurons.mp4 by Arijit Ghosh (1304952)

“…Overexpression of kininogen and exogenous bradykinin administration significantly increased pentylenetetrazole-induced seizure susceptibility in mice. …”

Table 1_Assessment of various salt water stresses with mineralization on plant growth and antioxidants activity to regulate oxidative stress and ROS scavenging of halophyte ice pla... by Xinchao Ma (22249096)

“…The results indicated that the T6 treatment (saline-alkali solution of 30 g/L) strongly decreased the plant height, stem thickness, leaf area and SPAD value of ice plants, and obviously suppressed the shoot and root biomass with the increase in salinity. …”

Data Sheet 1_Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes.zip by Alessia Cavallo (13036581)

“…Th1/Th17 cytokines significantly inhibited the high calcium-induced synthesis of phospholipids (PCs, PEs, SMs), and short-chain ceramides, while the synthesis of ceramides with medium to long carbon chains was upregulated. …”

Image 5_Interleukin-6/soluble IL-6 receptor-induced secretion of cathepsin B and L from human gingival fibroblasts is regulated by caveolin-1 and ERK1/2 pathways.tiff by Ayaka Goto (20858771)

“…</p>Results<p>Cathepsins B and L were secreted in their precursor forms from HGFs, with significantly elevated protein levels observed at 24, 48, and 72 h post-IL-6/sIL-6R stimulation. …”

Data Sheet 1_Association between polychlorinated biphenyls and hypertension risk: a systematic review and meta-analysis.pdf by Seyedeh Fatemeh Hamzavi (21104606)

“…Background and Aim<p>Hypertension (HTN) is a widespread global health challenge, and its increasing prevalence is attributed to individual and environmental risk factors. …”

Supplementary Material for: Effect of Migraine Abortive Drugs on Benign Paroxysmal Positional Vertigo Odds - A Database Analysis by figshare admin karger (2628495)

“…Results: As expected, the female subject population had significantly higher prevalence of migraine (17.06% vs 7.26%, p<0.0001) than the males. …”

Supplementary file 1_A risk-stratified model for predicting endometrial atypical hyperplasia and cancer to guide biopsy decisions in asymptomatic postmenopausal women.docx by Shanshan Wu (348762)

“…The risk-stratified model demonstrated clinical utility: using a ≥ 5% risk threshold, biopsy would be recommended for 17% of patients (sensitivity 70.8%, specificity 84.4%); at a ≥ 10% threshold, biopsy would be recommended for 4.3% of patients (requiring 3.64 biopsies per true positive case).</p>Discussion<p>The risk of EAH and EC among asymptomatic postmenopausal women varies significantly based on clinical factors. …”

Utilizing and optimizing non-disrupted lines for evacuating passengers in Urban rail transit networks during disruptions by Lebing Wang (20419496)

“…The inclusion of a Path-Sized Logit model within the optimization framework accurately reflects passenger path-choice behaviours, while an iterative algorithm is introduced to tackle the nonlinear models. Applied to a case study of the Zhengzhou Metro, the implementation of the disruption management schemes obtained from these models and algorithm significantly increases the number of affected passengers completing their trips and minimizes passenger delays during disruptions, thereby enhancing the urban rail transit network's resilience. …”

Data Sheet 1_Genetic testing enhances diagnosis in critically ill neonates: insights from the first Colombian cohort.pdf by Paula Rueda-Gaitán (22100057)

“…Introduction<p>The integration of genetic testing in pediatrics has advanced significantly in recent years. The incorporation of technologies such as Next Generation Sequencing (NGS) and array-based Comparative Genomic Hybridization (aCGH) in increasingly younger patients has accelerated the transition toward precision medicine.…”

Table 2_Risk factors for antimicrobial-resistant Enterobacterales in dogs: a systematic review.xlsx by Esa Karalliu (11130876)

“…Of these, antimicrobial use was the most common risk factor significantly associated with AMR-Enterobacterales (19/28), followed by raw diet (9/14) and hospitalization (8/19). …”