Image1_Efficacy and Safety of a Polysaccharide-Based Natural Substance Complex in the Treatment of Obesity and Other Metabolic Syndrome Components: A Systematic Review.TIF by Giuseppina Guarino (6795282)

“…Policaptil Gel Retard^® (PGR), an oral macromolecule complex based on polysaccharides, has been demonstrated to significantly reduce body weight, peak blood glucose (BG) levels, insulin levels, and lipid levels, providing an interesting non-pharmacological therapeutic option for MetS-associated metabolic abnormalities, especially in younger patients.…”

Image 1_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.tif by Zhenzhen Gu (21488168)

“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”

Table 5_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Image 1_The immunomodulatory and antitumor properties of the bacterial metalloprotease Oligopeptidase A are mediated by TLR4/MyD88/TRIF and MAPK signaling pathways.tif by Priscila Silva (556743)

“…</p>Results<p>Heat-inactivated OpdA significantly reduced metastasis, dependent on tumor-specific CD4+ and CD8+ T cells and IFN-γ, both locally and systemically, with decreased IL-10 levels suggesting a proinflammatory environment. …”

Data Sheet 1_Molecular insights into Atorvastatin’s role in delaying intervertebral disc degeneration.zip by Yupeng Li (507508)

“…</p>Results<p>Pretreatment with 10 μM atorvastatin significantly improved the survival rate of NPCs exposed to hydrogen peroxide (H₂O₂) and reduced apoptosis. …”

Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif by Yang Jing (2231179)

“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”

Table 1_Seeds of success: seed biology and germination response of Gazania weed in Australia.xlsx by Muhammad Adnan (678952)

“…Seedling emergence and root length decreased with increasing burial depth and no emergence was observed at 6 cm depth. …”

Data Sheet 1_Global burden of nasopharyngeal carcinoma attributable to alcohol use: a 1990–2021 analysis with projections to 2040.pdf by Zhenyi Lu (22004786)

“…</p>Results<p>From 1990 to 2021, global ASMR declined from 0.31 to 0.19 per 100,000 population (AAPC −1.66; 95% CI −1.79 to −1.52) and ASDR fell with an AAPC of −1.72 (95% CI −1.87 to −1.57). Male ASMR decreased from 0.42 to 0.27 per 100,000 (AAPC −1.60), and female ASMR from 0.21 to 0.12 per 100,000 (AAPC −2.25). …”

DataSheet1_Causal association between inflammatory bowel disease and acute pancreatitis: a two-sample bidirectional mendelian randomization study.PDF by Cong Zhang (582922)

“…Interestingly, AP was suggestively associated with a decreased risk of CD (OR = 0.797, 95% CI = 0.637-0.997, p = 0.047). …”

Table 2_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx by Jingjing Chen (293564)

“…</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”

Table 2_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx by Zhenzhen Gu (21488168)

“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”

Chromatin accessibility profiling of Treg cells in acute urticaria by Leilei Wen (3551444)

“…In this study, we found that the frequency of Tregs in peripheral blood mononuclear cells (PBMCs) was decreased in patients with acute urticaria compared with normal controls by flow cytometry. …”

Image 2_The alteration of the sensorimotor network in trigeminal neuralgia after microvascular decompression surgery: a follow-up study using independent component analysis.tif by Yan Zhang (8098)

“…</p>Results<p>Compared to the HC, increased activity was observed in the right frontal operculum cortex, right insular cortex, right inferior frontal gyrus (pars opercularis), and right frontal pole in TN patients. Conversely, decreased activity was found in the right cerebellum (lobule IX) and left cerebellum (lobules VIII and IX). …”

Table 1_Machine learning identifies neutrophil extracellular traps-related biomarkers for acute ischemic stroke diagnosis.docx by Haipeng Zhang (3413288)

“…NDEGs were significantly enriched in immune regulation and leukocyte apoptosis (GO) and NETs formation pathway (KEGG). …”

Table 1_Integrated analysis of miRNAs-mRNAs in skeletal muscle development revealed that novel-miR-766 affects myoblast differentiation and myofiber-type formation in sheep.xlsx by Zhenzhen Gu (21488168)

“…In vitro assays revealed that myoblast differentiation and myotube formation were significantly inhibited by MYH3 knockdown via siMYH3 and that novel-miR-766 targets and decreases the expression of MYH3. …”

Table 4_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.docx by Thiago Henrique Teodoro (20703731)

“…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …”

Data Sheet 1_Preparation of biosorbent from avocado seeds for preconcentration and simultaneous extraction of trace parabens in environmental wastewater samples.docx by Aluwani Sharon Nephiphidi (22696835)

“…The reusability and regeneration adsorption percentage recoveries significantly decreased after the fifth cycle. Parabens extraction using the 30% KOH- magnetic activated carbon was considered a capable biosorbent for the extraction of parabens because it demonstrated a strong potential for extracting parabens pollutants simultaneously in wastewater samples.…”

Table 4_Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model.xls by Zhijian Zha (19451405)

“…</p>Results<p>In the danazol-induced CPP model, luteolin treatment significantly decreased the abundances of Estradiol (E2), luteinizing hormone serum, and follicle-stimulating hormone in sera; reduced organ coefficients and ovarian and uterine wet weights; and delayed vaginal opening. …”

Image_2_Angiotensin-I-converting enzyme inhibitory peptides from eel (Anguilla japonica) bone collagen: preparation, identification, molecular docking, and protective function on H... by Huan Xiang (460100)

“…Treatment with GPPGPPGL significantly increased nitric oxide secretion (p < 0.01) and decreased endothelin-1 (ET-1) production in HUVECs.…”

Table 1_The development of the neurosurgery workforce in Austria over the past quarter century: is more always better?.xlsx by Mario Mischkulnig (11659318)

“…Growth in neurosurgeon density significantly outpaced both population growth (+ 14.3%) and the overall increase of specialist physicians (+ 77.4%, p = 0.001). …”