Image 1_Insights into the alteration of vaginal microbiota and metabolites in pregnant woman with preterm delivery: prospective cohort study.tif by Lihua Wang (14548)

“…In addition, vaginal metabolomics-based LC-Orbitrap-MS/MS revealed that the contents of 2-Piperidone, Melphalan, N-acetylputrescine, Obatoclax, Eurostoside, Pregnanediol 3-O-glucuronide, O-Phospho-L-serine, 1-Kestose and N-arachidonylglycine were significantly decreased in the PrPG group compared with the PrTG group, while Acenocoumarol, Isopyrazam, Pentosidine, hexose, 7-Hydroxymitragynine, PE, Tamoxifen and 1-Deoxynojirimycin contents were significantly increased. …”

Clinical observation and immune effect of high-intensity focused ultrasound (HIFU) treatment on patients with colorectal cancer liver metastasis by Shasha Wang (346796)

“…Post-treatment serum IL-6 levels decreased significantly (<i>p</i> < 0.001). OS was significantly better in the HIFU + chemotherapy group compared to chemotherapy-only (<i>p</i> < 0.0001).…”

Supplementary file 1_Ecosystem carbon storage and carbon metabolizing microorganisms in three types of grasslands on the Qinghai-Tibet Plateau.docx by Qian Liu (135614)

“…The relative abundance of carbon-fixing microorganisms Thiobacillus, Mesorhizobium, Azospirillum, and Methylibium significantly increased grassland carbon storage, while the relative abundance of chitinase-producing microorganisms Cellulomonas and Stenotrophomonas significantly decreased it.…”

Table 1_Insights into the alteration of vaginal microbiota and metabolites in pregnant woman with preterm delivery: prospective cohort study.docx by Lihua Wang (14548)

“…In addition, vaginal metabolomics-based LC-Orbitrap-MS/MS revealed that the contents of 2-Piperidone, Melphalan, N-acetylputrescine, Obatoclax, Eurostoside, Pregnanediol 3-O-glucuronide, O-Phospho-L-serine, 1-Kestose and N-arachidonylglycine were significantly decreased in the PrPG group compared with the PrTG group, while Acenocoumarol, Isopyrazam, Pentosidine, hexose, 7-Hydroxymitragynine, PE, Tamoxifen and 1-Deoxynojirimycin contents were significantly increased. …”

Table 1_Nitrite exposure on gills of Oreochromis niloticus: structure change, immune response, and apoptosis.xlsx by Chaowei Song (20639240)

“…Nitrite exposure significantly elevated serum catalase (CAT) activity and decreased superoxide dismutase (SOD) activity. …”

dataset; Visualizing Contribution Levels in Group Programs: A Dot-Voting Peer-Assessment Approach by Yuta Sakamoto (17860652)

“…Specifically, groups of eight members exhibited significantly higher variability in contributions compared to groups of four members, showing a moderate positive correlation. …”

community_experiment_and_pure_culture.xlsx by Wen-Wen Huang (22122439)

“…In both experiments, PE and PVC significantly reduced viral abundances. However, their effects on bacterial abundances were context-dependent. …”

Table 1_Biochar-based fertilizer increases soil nutrients and enhances tea quality: a metabolomics-based analysis.docx by Zhenyu Yang (427524)

“…Further metabolomics analysis revealed that BF2 treatment significantly elevated the levels of amino acids, including theanine, threonine, proline, valine, and glutamic acid, while decreasing catechins including C, EC, and EGCG, thus leading to reduced bitterness and astringency and enhanced freshness. …”

Coconut shell activated carbon (CSAC) reinforced municipal sludge by high pressurized electro-dewatering with constant voltage gradient by Binqi Rao (22300677)

“…The results indicated that under a constant voltage gradient of 36 V/cm, the moisture content (<i>M_c</i>) of sludge significantly decreased from 88% to 64%, and there was a noticeable improvement in the resistance and temperature of sludge cake compared to the constant voltage mode. …”

Fibroblast growth factor 18 stimulates chondrocyte proliferation by modulating FOXN2 to mitigate post-traumatic osteoarthritis in a mouse model by Gao Xi (22574101)

“…Intra-articular delivery of FGF18 in destabilized medial meniscus (DMM)-induced PTOA mice significantly reduced cartilage erosion and markedly decreased synovial thickening compared to saline-treated controls, with improved cartilage matrix integrity. …”

Supplementary file 1_Colonizable probiotic Lactobacillus paracasei R3 enhances ICI therapy via modulating PBMCs differentiation.docx by Wencan Song (21477434)

“…Our results also showed the rapid adherence of L.p R3 to intestinal epithelial cell membrane, and promoted intestinal epithelial cell expression of mucin mRNA, led to the long maintenance of L.p R3 in colon and cecum in mice. L.p R3 significantly elevated the levels of macrophages, CD4⁺T cells and CD8⁺T cells in PBMCs while simultaneously decreasing the level of programmed cell death protein 1 (PD-1) on the surface of CD4⁺T cells and CD8⁺T cells. …”

Genome-wide association analysis provides insights into the genomics and extracellular expression of <i>Staphylococcus aureus</i> proteases by Shuxian Li (20556455)

“…To identify the genetic variation underlying this variation in protease expression, we employed a <i>k</i>-mer-based genome wide association study, identifying 68 genes with polymorphisms significantly associated with proteolytic activity. Population-scale genomic variation was compared with strains from a sequenced- defined transposon library, validating the function of 27 loci that were significantly associated with decreased protease expression. …”

Diurnal Temperature Fluctuation Alters the Toxicity of Insecticides: the Role of the Temperature Coefficients of Insecticide by kun xing (20609528)

“…The findings revealed that wide amplitude significantly decreased adult fecundity, daily nymph reproduction, and the intrinsic rate of increase, while it significantly enhanced early fecundity. …”

Data Sheet 1_The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation.docx by Qian Qian (45749)

“…Neutrophil-related markers like IL6, IL8, and neutrophil extracellular traps (NETs) were significantly elevated in this model. Inhibiting neutrophils production significantly improved airway inflammation and lung function. …”

Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein by Xiangchao Jia (21392720)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

Table 1_Regulation of DNA methylation in lesional tissue of children with atopic dermatitis.docx by Demet Kartal (20817926)

“…</p>Results<p>The mRNA expression levels of DNMT3A genes were significantly increased, while the mRNA expression levels of DNMT3B, TET1, and TET2 genes were statistically significantly reduced in the lesional tissue of patients compared to the control group. …”

Supplementary Material for: Impact of robotic surgery on postoperative pancreatic fistula for high-risk pancreaticojejunostomy after pancreatoduodenectomy by Fuji T. (13875467)

“…These results suggest that RPD may be significantly associated with a decreased incidence of CR-POPF in high-risk anastomoses.…”

Low temperature reduces byssus adhesion of highly invasive golden mussels: Influencing mechanisms and antifouling implications by Miaolian Zhang (21974951)

“…Our results showed that low-temperature exposures significantly reduced adhesion rates of golden mussels, primarily by limiting byssus production associated with impaired synthesis and secretion of byssal proteins and decreasing byssus breaking force. …”

Data Sheet 1_Nutraceutical supplement slim reshaped colon histomorphology and reduces Mucispirillum schaedleri in obese mice.docx by Jessica Alves Freitas (20974076)

“…</p>Results<p>Our results demonstrated that Slim supplementation significantly improved lipid metabolism, reshaped colon histomorphology, and decreased levels of Mucispirillum schaedleri, which were correlated with VLDL-c and triglycerides.…”

Areal densities of single targets in the feeding areas of northern and southern resident killer whales. by Burak Saygili (19832062)

“…Prey densities differed significantly between feeding areas, and generally decreased as the fish migrated from west to east towards the Fraser River. …”