Data Sheet 1_Role of insulin signaling dysregulation in pulmonary vascular remodeling in rats with monocrotaline-induced pulmonary arterial hypertension.pdf حسب Gufeng Gao (16835753)

"…Analysis of lung tissues revealed enhanced levels of p-PKC, p-IRS-1(Ser318), and p-ERK, whereas the expression of total IRS-1 decreased significantly (p < 0.05). In PASMCs stimulated with PDGF-BB, a similar trend of increased p-PKC, p-IRS-1(Ser318), and p-ERK levels was observed, along with a decrease in IRS-1 expression. …"

Image4_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg حسب Elena Chiappini (304802)

"…Compared to what participants reported for the treatment of non-prolonged fever, a significant decrease in the prescription of paracetamol as first-choice drug in children with FUO was observed (80.5%; P < 0.0001). …"

Data Sheet 1_Efficacy and safety of reduning injection for severe pneumonia: a systematic review and meta-analysis.docx حسب Yan Wang (15435)

"…</p>Conclusion<p>The administration of RDN injection as an adjunct therapy for SP can enhance clinical efficacy, reduce fever duration, accelerate cough resolution, shorten the time for lung rales to resolve, accelerate chest X-ray improvement, and decrease hospitalization duration. Further well-designed and standardized large sample clinical studies are needed for validation.…"

Supplementary file 2_Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study.do... حسب Nian Jiang (1338381)

"…Lowering the METS-IR index below 38.1 through lifestyle changes and diet control can significantly reduce the risk of cognitive impairment and may decrease the incidence of dementia.…"

Table 1_Pre-COVID era pediatric disease incidence in Kazakhstan: regional panel data analysis of multiple disease groups (2010–2019).xlsx حسب Nurlan Smagulov (21510632)

"…A 1% increase in population density correlated with a 1.05% decrease in respiratory disease incidence (p = 0.008), whereas unemployment was linked to a 0.41% rise (p = 0.029). …"

Image4_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Table 6_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx حسب Bin Liao (714989)

"…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …"

Image6_A distinct immune landscape in anti-synthetase syndrome profiled by a single-cell genomic study.jpeg حسب Jiayu Ding (12005975)

"…</p>Results<p>After meticulous annotation of PBMCs, we noticed a significant decrease in the proportion of mucosal-associated invariant T (MAIT) cells in ASS patients compared to HCs, while there was a notable increase in the proportion of proliferative NKT cells. …"

Data Sheet 3_Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy.csv حسب Ben Wang (250897)

"…Analysis of the human transcriptome data revealed a significant negative correlation between LXRα and S100A8 (R = −0.98, p < 0.001).…"

Data types and their sources. حسب Firdissa Sadeta Tiye (21222102)

"…Conversely, land areas occupied by cultivated land, Erica forest, grassland, and herbaceous plants are projected to decrease by 28.52%, 3.28%, 19.03%, and 6.55%, respectively. …"

Table4_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.xlsx حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Table 1_Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat.docx حسب Shellye González-González (20517563)

"…In contrast, DLAN male offspring exhibited a significant decrease in social play behavior compared to LD animals, which was associated with higher numbers of microglia in the NAc that had more ramified morphology. …"

Treatment with TCA and S1P2 agonist induces S1PR2 expression and attenuates ROCK1/RHOA expression; inhibition of S1PR2 reverses TCA- or S1P2-mediated effect on ROCK1/RHOA expressio... حسب Aya Miyagawa-Hayashino (386487)

"…(C) <i>S1PR2</i> mRNA expression was significantly increased with TCA or S1P2 agonist stimulation as compared with the control and significantly reduced after pretreatment with JTE-013, an antagonist of S1PR2. …"

Table1_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.xlsx حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Data Sheet 1_Application of radiomics-based prediction model to predict preoperative lymph node metastasis in prostate cancer: a systematic review and meta-analysis.docx حسب Yanghuang Zheng (21575123)

"…The meta-analysis showed significant heterogeneity among the included studies. …"

Location map of the study area. حسب Firdissa Sadeta Tiye (21222102)

"…Conversely, land areas occupied by cultivated land, Erica forest, grassland, and herbaceous plants are projected to decrease by 28.52%, 3.28%, 19.03%, and 6.55%, respectively. …"

ANOVA for 7-MH yield. حسب Juthamart Maneenet (15999769)

"…<div><p>Pancreatic cancer presents a significant therapeutic challenge characterized by poor survival rates, leading to development of innovative treatment strategies. …"

Raw images of Western blot experiment. حسب Juthamart Maneenet (15999769)

"…<div><p>Pancreatic cancer presents a significant therapeutic challenge characterized by poor survival rates, leading to development of innovative treatment strategies. …"

Image4_Predicting acute lung injury in infants with congenital heart disease after cardiopulmonary bypass by gut microbiota.jpeg حسب Lan Jiang (57811)

"…The microbiota diversity was low in the CPB-ALI group with high pathogen abundance and significant decrease in Bacteroides, while the opposite was observed in the CPB-NALI group. …"

Image 1_The hemoglobin, albumin, lymphocyte, and platelet score as a useful predictor for mortality in older patients with hip fracture.jpeg حسب Zhicong Wang (810566)

"…For each unit increase in the HALP score, there was a significant decrease in 90-day mortality by 1.1% and in overall mortality by 1.0% (all p < 0.05). …"