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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
time increased » rate increased (Expand Search), use increased (Expand Search)
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19401
Data_Sheet_1_Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1G93A mice.docx
Published 2024“…Disease progression upregulated gene transcripts for pro- and anti-inflammatory cytokines, and IFN β treatment significantly decreased mRNA expression for IL4. Overall, the present results demonstrate that a low dosage of IFN β shows therapeutic potential by increasing MHC-I expression, resulting in neuroprotection and immunomodulation.…”
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19402
Supplementary file 2_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx
Published 2025“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”
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19403
The relationship between serum uric acid and gastrointestinal bleeding in peritoneal dialysis patients: a propensity score analysis
Published 2024“…In subgroups, the interaction between higher levels of uric acid and utilizing proton pump inhibitors was significant (P for interaction = 0.034). Further research found that taking proton pump inhibitors could decrease the risk of gastrointestinal bleeding in peritoneal dialysis patients accompanied high levels of uric acid.…”
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19404
Data Sheet 1_The effect of repetitive and Deep Transcranial Magnetic Stimulation on quantitative electroencephalography in major depressive disorder.pdf
Published 2025“…Patients who exhibited lower alpha activity in the left fronto-central region and higher gamma activity in the right prefrontal region following rTMS showed more significant improvements in depression symptoms. Similarly, those whose beta activity increased in the left prefrontal region but decreased in the right prefrontal region after rTMS tended to have greater reductions in depression and anxiety severity. …”
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19405
Image 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg
Published 2025“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”
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19406
Image 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.tif
Published 2025“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”
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19407
Table 1_Functional analysis of NtPDX2 in Nicotiana tabacum L. associated with stem development.docx
Published 2025“…By conducting both constitutive overexpression and homozygous knockout studies of the NtPDX2, we observed a significant increase in vitamin B<sub>6</sub> content in the stem tissues of overexpressing plants (up to 150%), while knockout plants showed a decrease to 60%. …”
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19408
Image 1_Quantifying the split-elbow sign: a comprehensive study in amyotrophic lateral sclerosis.tif
Published 2024“…Furthermore, there was a notable decrease in SEI<sub>MUNIX</sub> values as the disease progressed (p < 0.001). …”
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19409
Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization
Published 2024“…<p dir="ltr"><b>Background:</b><b> </b>Heatstroke (HS) is a critical medical condition resulting from increased body temperatures, which can lead to significant damage to the central nervous system (CNS). …”
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19410
Supplementary file 1_Loss of SynDIG4/PRRT1 alters distribution of AMPA receptors in Rab4- and Rab11-positive endosomes and impairs basal AMPA receptor recycling.pdf
Published 2025“…We did not observe any change in baseline endocytosis; however, we did observe a significant decrease in recycling of GluA1-containing AMPARs in cultured hippocampal neurons from mice lacking SynDIG4. …”
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19411
Table 1_Association between cardiometabolic Index and obstructive sleep apnea and the mediating role of smoking: a cross-sectional study.docx
Published 2025“…Additionally, the findings from the threshold effects analysis indicate that maintaining CMI within an appropriate range can significantly decrease the likelihood of developing OSA.…”
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19412
Initial evaluation of an intervention to address provider implicit bias in pediatric sickle cell disease pain care: A mixed methods pilot study
Published 2025“…Significant differences in HCP ratings were found between types of HCPs (<i>P</i> < 0.001), but no effects were attributable to condition, time, virtual patient race, or diagnosis. …”
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19413
Table 1_Salvage chemotherapy in the intensive care unit: a case report of successful treatment of a critically ill patient with metastatic testicular germ cell tumor.docx
Published 2025“…<p>Testicular cancer, predominant among young males, poses a significant healthcare challenge with varying incidence rates across European regions. …”
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19414
Table1_Identification of key biomarkers and therapeutic targets in sepsis through coagulation-related gene expression and immune pathway analysis.docx
Published 2024“…<p>Sepsis, characterized by a widespread and dysregulated immune response to infection leading to organ dysfunction, presents significant challenges in diagnosis and treatment. In this study, we investigated 203 coagulation-related genes in sepsis patients to explore their roles in the disease. …”
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19415
Image 4_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg
Published 2025“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”
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19416
Data Sheet 1_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.pdf
Published 2025“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”
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19417
Supplementary file 8_Global burden of pancreatitis among individuals aged 15–39 years: a systematic analysis from the 2021 GBD study.docx
Published 2025“…Background<p>Pancreatitis represents a significant global public health challenge, yet there is a lack of comprehensive analyses focusing on the burden of pancreatitis and its long-term trends among young individuals aged 15–39 years.…”
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19418
Overview of direct and indirect associations.
Published 2025“…<div><p>Background</p><p>Pain is associated with a decrease in physical activity for most individuals. …”
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19419
Additional file 1 of Genome-wide association study of agronomic traits in winter wheat (Triticum aestivum L.) using a custom SNP marker set
Published 2025“…Additional file 9.xlsx Significant marker-trait associations.…”
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19420
Data Sheet 1_Effects of cattle manure and sludge vermicompost on nutrient dynamics and yield in strawberry cultivation with distinct continuous cropping histories in a greenhouse.d...
Published 2025“…In both substrate types, there was a substantial increase in microbial population and enzyme activity, accompanied by a significant decrease in phenolic acid content. During the senescence stage, the use of cattle manure vermicompost led to enhancements in plant height, leaf area, and root length, with increases ranging from 15.01% to 32.77% and 23.75% to 32.78% across the two substrate types compared to the control group. …”