Image 1_Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats.pdf by Silvia Granata (2678077)

“…Furthermore, inactivation of key androgenic enzymes, such as 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase, together with decreased testosterone synthesis suggest a potential impairment of male gonadal function.…”

Table 4_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx by Ziqi Han (12840074)

“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”

Image 2_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Table 2_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Cardiopulmonary exercise response at high altitude in patients with congenital heart disease: a systematic review and meta-analysis.pdf by Marco Vecchiato (4591219)

“…Nevertheless, the patients with CHD showed a smaller decrease in peak workload [10.61 W (95% CI: 2.33–18.88)] and peak saturation [1.22% (95% CI: 0.14–2.30)] between LA and HA compared to the controls. …”

DataSheet1_A lightweight MHDI-DETR model for detecting grape leaf diseases.pdf by Zilong Fu (20392494)

“…The original residual backbone network was improved using the MobileNetv4 network, significantly reducing the model’s computational requirements and complexity. …”

Image 4_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf by Ruixian Liu (5743817)

“…</p>Results<p>In the treat group, colitis symptoms in mice were significantly improved, and there was a decrease in proportion of macrophages and protection of intestinal mucosal integrity-indicating anti-inflammatory effects of FX1. …”

Table 1_Manure substitution for chemical nitrogen enhances soil quality without compromising maize yield: a short-term field experiment in Northeast China.xlsx by Chao Zhou (471522)

“…</p>Results and disscussion<p>Compared to CK, only 25% substitution rate maintained maize yield, while 50‒100% manure substitution decreased maize yield by 15.9‒67.2%. This is primarily due to the decrease in root biomass (13.5‒29.1%), length (14.8‒43.3%), surface area (14.1‒48.8%) and volume (17.9‒53.4%). …”

Table 2_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.xlsx by Giulia Santarelli (14246638)

“…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Image 1_Cardiopulmonary exercise response at high altitude in patients with congenital heart disease: a systematic review and meta-analysis.tif by Marco Vecchiato (4591219)

“…Nevertheless, the patients with CHD showed a smaller decrease in peak workload [10.61 W (95% CI: 2.33–18.88)] and peak saturation [1.22% (95% CI: 0.14–2.30)] between LA and HA compared to the controls. …”

Data Sheet 1_High intensity human activity limits ultra-high altitude soil microbial community dispersal and keystone taxa distribution in southeastern Tibetan Plateau.docx by Wenzu Liu (22364023)

“…Human activities increase the complexity of microbial networks but decrease the stability of soil micro-ecosystems. As elevtation increases, the dispersal limitation of microbial communities decreases (total effect size: bacterial = −0.705, fungal = −0.745). …”

Data Sheet 1_Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish.docx by Ying–Ying Zhang (21776942)

“…Post-exposure assays (mirror test and dyadic interaction) revealed that Mix significantly reduced the frequency of approaching mirror, the attack mirror duration, and the frequency of chasing un-exposed fish, indicating a decrease in aggressive behaviour in Mix-fish. …”

Data Sheet 1_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.docx by Chengli Yu (1445185)

“…Early detection and removal of precancerous lesions during the adenoma-carcinoma sequence can significantly reduce CRC risk. However, current clinical practice lacks rapid, noninvasive screening tools for reliable adenoma detection.…”

Supplementary Material for: Feedback from human instructors is superior to guidance by a virtual reality simulator when learning flexible bronchoscopy – a randomized controlled tri... by figshare admin karger (2628495)

“…[Results] All three groups showed an improvement in SP, DC, PT and NASA-TLX during their 12 procedures (P<.05), without a decrease in performance three weeks later (P>0.05). …”

Table 5_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx by Chengli Yu (1445185)

“…Early detection and removal of precancerous lesions during the adenoma-carcinoma sequence can significantly reduce CRC risk. However, current clinical practice lacks rapid, noninvasive screening tools for reliable adenoma detection.…”

Table 1_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).xlsx by Ziqi Han (12840074)

“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”

Ganaxolone: A Review in Epileptic Seizures Associated with Cyclin‑Dependent Kinase‑Like 5 Deficiency Disorder by Sheridan M. Hoy (4897468)

“…In a multinational phase III study (Marigold), 17 weeks’ therapy with adjunctive ganaxolone, administered orally three times daily with food, significantly reduced 28-day major motor seizure frequency from baseline versus placebo in patients aged 2–19 years with CDD-associated refractory epilepsy. …”

Image 1_The activity of cell-free supernatant of Lactobacillus crispatus M247: a promising treatment against vaginal infections.png by Giulia Santarelli (14246638)

“…We observed a slight decrease in the microbial burden following LcM247 administration, while treatment with CFS significantly reduced microbial growth compared to control and antimicrobial compounds. …”

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx by Ameya Joshi (1290186)

“…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…”

Data Sheet 1_Stellate ganglion blockade under ultrasound-guidance and the physiological responses in the rat.pdf by Robert M. N. Tran (20539130)

“…Heart rate (HR) was significantly decreased after administration of lidocaine (344 ± 32 to 289 ± 47 bpm; p = 0.015, pre-vs. after-injection), but not after normal saline, into the right SG. …”