Showing 3,361 - 3,380 results of 21,342 for search '(( significant decrease decrease ) OR ( significant ((treatment decreased) OR (small decrease)) ))', query time: 0.46s Refine Results
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    Discovery of MKP10241, a Novel Small Molecule Targeting the GPR119/Incretin Axis to Treat Metabolic Disorders by Santosh Kumar Rai (22382996)

    Published 2025
    “…We have developed a potent GPR119 agonist, MKP10241, which has elevated cyclic adenosine monophosphate (cAMP) levels in the GPR119 expressing cell line and reduced blood glucose levels and HbA1c in acute models and a chronic diabetic mouse model. Chronic treatment of MKP10241 in DIO-mice exhibited marked reduction in body weight and feed intake at tested doses, which was associated with decreased blood glucose level, lipid parameters, and body fats. …”
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    Fig 20 - by Zhezhe Zhang (19704587)

    Published 2024
    Subjects: