Table 3_Predicting ventilator-associated lower respiratory tract infection outcomes using sequencing-based early microbiological response: a proof-of-concept prospective study.docx by Ji Zhou (481629)

“…The RQR was calculated as the quantification of A. baumannii determined by QtNGS after treatment to pretreatment. RQR significantly increased on day 4 in the non-survival group (median 5.285), and decreased in the survival group (median 0.1864). …”

Image 4_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif by Inssaf Berkiks (15350248)

“…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …”

Table1_Management of pediatric ankle fractures: comparison of biodegradable PLGA implants with traditional metal screws.xlsx by Hermann Nudelman (19971882)

“…For this reason, they reduce the burden on the patient and the healthcare provider while simultaneously decreasing the risk of complications, such as infections or problems due to general anesthesia.…”

DataSheet1_Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study.pdf by Yongming Du (807059)

“…</p>Conclusion<p>This comprehensive MR analysis indicated that SLE, CeD, vitiligo, and AD caused an increased risk of POI, SIgAD was associated with a decreased risk of POI. These insights carry profound clinical implications, particularly emphasizing the early intervention for women with AIDs/POI who wish to preserve their reproductive potential or plan for future pregnancies.…”

Table 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.docx by Linjie Peng (12553717)

“…Moreover, TB001 treatment decreased the body weight and serum total cholesterol, LDL-cholesterol, and TNF-α levels in transplant recipients, indicating metabolic improvements. …”

Table 2_PitNET tissue deconvolution: tracing normal tissue residues and immune dynamics.xlsx by Mattia Dalle Nogare (22696022)

“…</p>Results<p>CIBERSORTx demonstrated the highest sensitivity (r > 0.85) for detecting pituitary cell types, although accuracy decreased for TME components. Application to ten GH-secreting PitNETs with known histological contamination and to public datasets consistently revealed residual normal tissue across hormone-secreting subtypes, excluding silent tumors. …”

Table 1_Safety and efficacy of canine recombinant IL-15 in mammary gland tumors.docx by Min-Hee Kang (811734)

“…Dogs in the rcIL-15 group showed significantly improved QoL, particularly in pain, appetite, and activity. …”

Hesperetin attenuates ischemia/reperfusion-induced acute kidney injury by regulating ferroptosis in mice by Xiaoyu Xie (2568607)

“…<p>Acute kidney injury (AKI) is a complex syndrome often resulting from ischemia/reperfusion (I/R) injury (IRI). Due to the significant role of ferroptosis in AKI pathogenesis, therapeutic strategies targeting ferroptosis could offer potential benefits in managing AKI. …”

Image 4_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Table 1_MicroRNA-27b alleviates septic cardiomyopathy by targeting the Mff/MAVS axis.docx by Xincai Wang (7819064)

“…</p>Results<p>Bioinformatics analysis revealed significant downregulation of miR-27b in SCM cardiac tissues (log2FC=-3.9, P<0.001). …”

Video 7_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.mp4 by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Table 3_Age-related trajectories of quality of life in community dwelling older adults: findings from the Survey of Health, Aging and Retirement in Europe (SHARE).docx by Sarah Mendorf (11632098)

“…The influence of age was less significant compared to ID and decreased significantly after the addition of covariates.…”

Image 1_The global burden of hypertension and its epidemiological impacts on adolescents and young adults: projections to 2050.jpeg by Chaofeng Niu (17746406)

“…</p>Results<p>From 1990 to 2021, the absolute numbers of hypertension-related deaths, Disability-Adjusted Life Years (DALYs), and Years Lived with Disability (YLDs) increased significantly globally. The age-standardized mortality rate and DALY rate decreased to some extent, while the YLDs rate increased slightly. …”

Data Sheet 1_Decoding population PM2.5 exposure in China: interplay of emissions, meteorology, and inequality (2013–2020).docx by Sujing Li (564578)

“…Meteorological conditions have generally mitigated PM_2.5 exposure, with the most significant dispersion effect in 2018. Notably, meteorology’s role in mitigating inequality in occupational exposure significantly decreased from 43.7% in 2013 to 4.5% in 2019, while its exacerbating effect on urban–rural inequality, contributing 43.7% in 2010, drastically reduced by 2020, even shifting to a slight alleviating role. …”

Table 1_Evaluating the effectiveness of integrated care in targeted therapy for patients with chronic lymphocytic leukemia.docx by Xin Liu (43569)

“…During the follow-up period, the lymphocyte count, white blood cell count, ESR, β2-microglobulin, and LDH levels of patients in the comprehensive nursing group significantly decreased, while immunoglobulin levels significantly increased. …”

Data Sheet 1_Global, regional, and national burden of acute glomerulonephritis from 1990 to 2021 and future trend predictions until 2036: a systematic analysis using the Global Bur... by Yangtian Jiao (21725018)

“…</p>Conclusion<p>Despite significant global progress, disparities persist, particularly in low- and middle-income regions. …”

Image 5_Ozone promotes macrophage efferocytosis and alleviates neuropathic pain by activating the AMPK/Gas6-MerTK/SOCS3 signaling pathway.tif by Shirong Ruan (15414081)

“…</p>Results<p>We found ozone at a concentration of 30μg significantly alleviated mechanical hypersensitivity in CCI mice and ozone significantly upregulates the phagocytic activity of BMDM. …”

Table 4_Comparative study of flow rate- and material-dependent human plasma protein adsorption on oxygenator membranes and heat exchanger materials.pdf by Katharina Große-Berkenbusch (21559466)

“…Protein adsorption to the membrane types did not vary to a large extent, but a decreased flow rate significantly reduced the differences in protein adsorption between both membrane types and led to the adhesion of significantly higher amounts of inhibitory proteins C1INH and α1-AT. …”

Table 1_Longitudinal relationships between daily activities, depressive symptoms, anxiety, and suicidality during the COVID-19 pandemic: a three-wave cross-lagged study.docx by Juhee Choi (2619733)

“…Background<p>The COVID-19 pandemic has caused significant unprecedented changes in lives. In particular, core daily activities, such as sleep, diet, physical activity, education, and social activities have significantly changed. …”

Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i> by Yingying Du (5877701)

“…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …”