Data Sheet 1_Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway.docx by Yumei Rong (11589031)

“…Mechanism studies demonstrated that LD₄-PDT could inhibit the NF-κB signaling pathway, downregulated the expression of the inflammatory factors’ tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and myeloperoxidase (MPO), increased the contents of glutathione (GSH) and superoxide dismutase (SOD) and decreased the content of malondialdehyde (MDA). Additionally, analysis of gut microbiota revealed that LD₄-PDT treatment could decrease the abundance of the Proteobacteria phylum in fecal samples, while no significant differences were observed in the Firmicutes, Bacteroidetes, or Actinobacteria phyla among the three groups using 16S rRNA analysis.…”

Image 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.pdf by Xu Zheng (296676)

“…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …”

Image 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.tif by Xu Zheng (296676)

“…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …”

Table 2_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx by Xu Zheng (296676)

“…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …”

Table 1_A comprehensive study of hip dislocation: global health burden from 1990 to 2021 and its predictions to 2030.docx by Xu Zheng (296676)

“…</p>Conclusion<p>The disease burden of hip dislocation remains a significant public health challenge. Data-driven analysis is pivotal for guiding clinical practice, shaping public health policies, and ensuring optimal allocation of healthcare resources. …”

Inference of cell-type proportions from bulk RNAseq and dynamics during myocardial infarction in α1A-AR-KO mice. by Brian Gural (21781982)

“…<b>(E)</b> Results from a Dirichlet regression modeling cell type proportion as influenced by cmAKO, MI, and their interaction, revealing significant effects on several cardiac cell types. …”

Data Sheet 1_Menthacarin, a proprietary combination of peppermint and caraway oil, alters cultured human fecal microbiota composition, resulting in increased SCFA production.pdf by Martin D. Lehner (3350846)

“…At the genus level, the most notable changes were significant increases in Bifidobacterium (+105.1 ± 78.4%) and several SCFA-producing genera accompanied by a significant decrease in genera containing members involved in pro-inflammatory processes. …”

Data Sheet 1_Mind the road: attention related neuromarkers during automated and manual simulated driving captured with a new mobile EEG sensor system.pdf by Joanna Elizabeth Mary Scanlon (13913817)

“…Background<p>Decline in vigilance due to fatigue is a common concern in traffic safety. Partially automated driving (PAD) systems can aid driving but decrease the driver's vigilance over time, due to reduced task engagement. …”

Table 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.docx by Zehao Jin (11408687)

“…Significant socioeconomic disparities were observed, with low-to-middle SDI regions bearing a disproportionate share (75.0%) of the global high non-optimal temperature-related mortality burden. …”

Impact of structural connectivity on dynamic functional connectivity associated with the stimulated regions in left DLPFC-tDCS protocol (F3a-Fp2c). by Yanqing Dong (8829548)

“…Warmer colors correspond to an increase in FC, while cooler colors correspond to a decrease in FC. The color bars indicate statistical t-values ().…”

DataSheet1_Efficacy and safety of danshen class injections in the treatment of coronary heart disease: a network meta-analysis.docx by Shuang Dai (1413496)

“…The results of NMA showed that, XD injection significantly enhances clinical efficacy; STS is more effective in reducing hs-CRP levels; DSDFSY shows better efficacy in decreasing IL-1 and increasing NO levels; DSCXQ has a greater advantage in reducing IL-6 levels; GXN is more effective in regulating SOD levels; and DH is better at reducing MDA levels.…”

Table 1_Structural and functional alterations in the contralateral hemisphere following pediatric intracranial surgery: a pilot longitudinal neuroimaging study.docx by Na Yan (450205)

“…</p>Conclusion<p>Our findings suggest that post-craniotomy structural and functional brain changes in children follow a subcortical-to-cortical trajectory, with structural alterations (decreased gray matter density) preceding functional activation. …”

Data Sheet 1_Therapeutic efficacy of a galactoglucan from Pleurotus citrinopileatus in constipation: modulation of aquaporin signaling and intestinal barrier.pdf by Yi Gao (112914)

“…The oral administration of PCP-g resulted in a significant reduction in constipation symptoms, as indicated by an increase in fecal water content, normalization of pellet formation, enhancement of total fecal mass, decreased latency to the first stool, and improved intestinal propulsion. …”

Table 2_The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China.docx by Yongyao Shen (20561210)

“…Despite a slight decreasing trend exists, the absolute number increased as much as twofold, particularly among males and seniors. …”

Table 1_The burden of chronic kidney disease attributable to high sodium intake: a longitudinal study in 1990–2019 in China.docx by Yongyao Shen (20561210)

“…Despite a slight decreasing trend exists, the absolute number increased as much as twofold, particularly among males and seniors. …”

Table 1_Coffee consumption as a double-edged sword for serum lipid profile: findings from NHANES 2005–2020.docx by Chaoyue Mo (21684056)

“…In females, HDL-C levels rose with coffee consumption up to 2.6 cups/day, after which they began to decline, showing an inverted U-shaped association. In males, a similar non-linear trend was observed for TG, with levels peaking at 3.0 cups/day before decreasing.…”

Data Sheet 1_Identification of potential biomarkers for lung adenocarcinoma: a study based on bioinformatics analysis combined with validation experiments.zip by Chuchu Zhang (2562154)

“…Among them, only TGFBR2 had a significant causal relationship with LUAD (p=0.04, b=−0.06), and it is a protective factor for LUAD. …”

Table 1_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.docx by Lianjie Ruan (22660265)

“…Multiplex immunofluorescence further demonstrated a significant reduction of macrophage accumulation in the peribronchial regions of the lung following carnosine administration. …”

Table 2_Carnosine as a protective metabolic mediator in inflammatory lung injury by inhibiting macrophage infiltration and M1-like polarization.xlsx by Lianjie Ruan (22660265)

“…Multiplex immunofluorescence further demonstrated a significant reduction of macrophage accumulation in the peribronchial regions of the lung following carnosine administration. …”

A well-resolved phylogeny of <i>Epilobium</i> (Onagraceae) taxa in the British Isles finds no correlation between genomic divergence and the outcome of hybridisation by Kaitlin Saward (22126620)

“…All were likely to be F₁ hybrids.</p> <p>We did not detect a significant relationship between parental divergence and hybridisation likelihood and/or hybrid fertility in <i>Epilobium</i> sect. …”