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18441
Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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18442
Table 1_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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18443
Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…Background<p>The phenomenon of population aging presents a significant global challenge, with the aging population in China steadily increasing. …”
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18444
Table 1_Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling.xlsx
Published 2024“…Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. …”
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18445
CCDC66 localizes to the axoneme and regulates primary cilium stability but not cilia formation in IMCD3 cells.
Published 2025“…Ciliary vesicle ectocytosis or fragments were categorized based on the size of the released EVs, vesicle < 500 nm and fragment > 500 nm, and plotted as a bar plot. (<i>p</i> values of Welch’s <i>t</i> test, **<i>p</i> = 0.0074, ***<i>p</i> = 0.0007, ns = not significant). …”
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18446
Differential mRNA expression of key metabolic and stress response genes in the <i>MYH7</i> Q315R mice.
Published 2025“…Clustering maps show significant changes in RNA expression (p < 0.05) greater than twofold or less than −2.0-fold (A and C). …”
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18447
Table 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.docx
Published 2025“…Co-infections were common, accounting for 69.5% of all infections, with two (40.1%), three (26.9%), and four-species combinations (19.8%) predominating. Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”
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18448
Image 1_Species diversity and risk factors of gastrointestinal nematodes in smallholder dairy calves in Kenya.tiff
Published 2025“…Co-infections were common, accounting for 69.5% of all infections, with two (40.1%), three (26.9%), and four-species combinations (19.8%) predominating. Male calves showed a significant association with both increased FEC and smaller heart girth, while FEC decreased with age. …”
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18449
Experimental Investigation of Hydrodynamic Characteristics in Industrial Pulsed Liquid–Liquid Extraction Column
Published 2025“…Overall, the flow regimes inside both columns differ significantly due to variations in internal components, which highlights the importance of parameter optimization tailored to specific engineering requirements in industrial applications and provides new insights when a dimensional analysis or similarity-based scaling approach is applied for the scale-up.…”
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18450
Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy
Published 2024“…In multivariable analyses, RBP3 remained significantly associated with a DR progression and history of DME. …”
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18451
Table 1_Sitagliptin phosphate ameliorates chronic inflammation in diabetes mellitus via modulating macrophage polarization.docx
Published 2025“…Moreover, histological analysis showed that compared with the Control group, the size of visceral adipocytes, hepatocyte lipid deposition and the ratio of M1/M2 macrophage were higher in the DM group, which were reversed by Sitagliptin phosphate treatments (P<0.05), insulin treatments did not have a significant effect (P>0.05). Mechanistically, Western blot showed that compared with the normal group, HG upregulated the expression of mTORc1 protein, P-65 phosphorylation and P-65 protein expression in Raw264.7 cells (P<0.05), downregulated the expression of IKKβ (P<0.05) and PPAR-γ proteins (P<0.05), Sitagliptin phosphate and insulin treatments rescued these changes. …”
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18452
Table 1_Lyophyllum decastes-derived polysaccharides alleviate DSS-induced colitis in mice by suppressing inflammation, enhancing intestinal barrier integrity, and restoring gut mic...
Published 2025“…Additionally, LDP improved intestinal barrier function by reducing MPO activity and enhancing occludin and ZO-1 expression. 16S rRNA sequencing revealed a significant restoration of gut microbiota diversity, with an increase in beneficial bacteria Muribaculaceae, Lactobacillus, and Lachnospiraceae, and a reduction in pathogenic bacteria Escherichia-Shigella. these findings suggest that LDP exhibits therapeutic effects in DSS-induced colitis through anti-inflammatory properties, enhancement of intestinal barrier function, and modulation of gut microbiota. …”
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18453
Table 1_Lumefantrine ameliorates DSS-induced colitis by targeting FLI-1 to suppress NF-κB signaling.docx
Published 2025“…Background<p>Current therapeutic options for inflammatory bowel disease (IBD) remain suboptimal due to limited efficacy, significant side effects, and high relapse rates, necessitating novel treatment strategies. …”
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18454
DataSheet1_Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren’s syndrome.pdf
Published 2024“…</p>Conclusion<p>TCM combined with CWM has a very significant effect on treating SS compared with CWM alone. …”
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18455
Table 1_Perception of health and illness and quality of life after total thyroidectomy for differentiated thyroid carcinoma: the PERSAM study.docx
Published 2024“…Mental health: more information to patients decreases the degree of stress and promotes ‘positive’ emotions. …”
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18456
Data_Sheet_1_Depression and health literacy among adolescents and adults in Germany: findings from two representative samples.pdf
Published 2024“…Introduction<p>Depressive disorders constitute a significant public health challenge. Health literacy might be an important factor to consider in prevention strategies for depressive disorders, which is why this study aimed at exploring the association between depressive symptom levels and severity and health literacy, along with additional sociodemographic factors.…”
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18457
Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus
Published 2025“…</p> <p>Compared to the HC group, SLE patients exhibited a decline in both Lyn mRNA and protein expression in PBMCs, with significant downregulation in the high SLEDAI group versus the low SLEDAI group and a notable reduction in the LN group relative to the non-LN group. …”
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18458
Table 1_Influence of summer transhumance practice in the Carpathians, Apuseni Mountains, Romania, on cattle milk production and quality.doc
Published 2025“…The results showed that, during the summer months (June–August), the milk yield in the TF was significantly lower. However, the milk fat content was significantly higher in June and July, and a highly significant negative correlation was found between the milk yield and the milk fat content (r<sub>s</sub> = −0.94). …”
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18459
Study of monopolar plate springback applying zoned multistage forming process
Published 2025“…The length and width of an MPP both exceed 150 mm, but the thickness of its raw material plate is less than 0.1 mm, posing a significant challenge to the uniformity of its thickness after forming. …”
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18460
Beyond species richness: grazing and fertilization shape temperate grassland stability through distinct stabilizing effects
Published 2025“…Alterations in land use, particularly grazing and fertilization, pose significant threats to the stability of grassland ecosystems. …”